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Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model

Zhang YD, Zhu ZS, Zhang D, Zhang Z, Ma B, Zhao SC, Xue F

This study aimed to investigate the effect of Patched-1 (PTC1) and PTC2 silencing in a rat model, on Hedgehog (Hh) pathway-mediated recovery from spinal cord injury (SCI). An analytical emphasis...
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Recommendations on management of gynecological malignancies during the COVID-19 pandemic: perspectives from Chinese gynecological oncologists

Wang Y, Zhang S, Wei L, Lin Z, Wang X, Wang J, Hua K, Cui M, Wang J, Wang S, Di W, Wang Y, An R, Xi M, Guo R, Zhou Q, Xie X, Xue F

The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 has rapidly spread globally. Cancer patients are at a higher risk of being infected...
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Lipids, Anthropometric Measures, Smoking and Physical Activity Mediate the Causal Pathway From Education to Breast Cancer in Women: A Mendelian Randomization Study

Li H, Hou L, Yu Y, Sun X, Liu X, Yu Y, Wu S, He Y, Wu Y, He L, Xue F

Purpose: We aimed to investigate whether obtaining a higher level of education was causally associated with lower breast cancer risk and to identify the causal mechanism linking them. Methods: The main...
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