- Novel Prognostic Nomograms for Hepatocellular Carcinoma Patients with Microvascular Invasion: Experience from a Single Center
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Xu L, Li L, Wang P, Zhang M, Zhang Y, Hao X, Yan L, Li B, Wen T, Xu M
- KMID: 2464314
- Gut Liver.
- 2019 Nov;13(6):669-682.
- doi: 10.5009/gnl18489
BACKGROUND/AIMS: Microvascular invasion (MVI) is an established risk factor for hepatocellular carcinoma (HCC). However, prediction models that specifically focus on the individual prognoses of HCC patients with MVI is lacking. METHODS:... -
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- Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway
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Xu Z, Hu J, Cao H, Pilo MG, Cigliano A, Shao Z, Xu M, Ribback S, Dombrowski F, Calvisi DF, Chen X
- KMID: 2438347
- Exp Mol Med.
- 2018 Jan;50(1):e417.
- doi: 10.1038/emm.2017.158
Hepatocellular carcinoma (HCC) is a deadly malignancy with limited treatment options. Activation of the AKT/mTOR cascade is one of the most frequent events along hepatocarcinogenesis. mTOR is a serine/threonine kinase... -
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- Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review
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Chen K, Xu M, Lu F, He Y
- KMID: 2545045
- Tissue Eng Regen Med.
- 2023 Aug;20(5):661-670.
- doi: 10.1007/s13770-023-00536-x
Extracellular matrix (ECM) components confer biomechanical properties, maintain cell phenotype and mediate tissue homeostasis. ECM remodeling is complex and plays a key role in both physiological and pathological processes. Matrix... -
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- Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study
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Wang Q, Dai H, Hou T, Hou Y, Wang T, Lin H, Zhao Z, Li M, Zheng R, Wang S, Lu J, Xu Y, Liu R, Ning G, Wang W, Bi Y, Zheng J, Xu M
- KMID: 2546436
- J Stroke.
- 2023 Sep;25(3):350-360.
- doi: 10.5853/jos.2023.00381
Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR). Methods We leveraged the summary statistics of GM (n=18,340... -
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- Influence of Mode of Delivery on Children’s Attention Deficit Hyperactivity Disorder and Childhood Intelligence
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Xu M, Yu X, Fan B, Li G, Ji X
- KMID: 2545139
- Psychiatry Investig.
- 2023 Aug;20(8):714-720.
- doi: 10.30773/pi.2022.0310
Objective To investigate whether differences exist in attention deficit hyperactivity disorder (ADHD) and intelligence between children born by cesarean delivery and those born by vaginal delivery. Methods This retrospective study included... -
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- Sturge-Weber Syndrome
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Chen L, Wu J, Xu M, Chen N, Yang Y
- KMID: 2383266
- Ann Dermatol.
- 2011 Nov;23(4):551-553.
Sturge-Weber syndrome (SWS) is a neurocutaneous syndrome, characterized by the association of facial port-wine hemangiomas in the trigeminal nerve distribution area, with vascular malformation(s) of the brain (leptomeningeal angioma) with... -
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- Silicon Dioxide Particles Deposited in Vessels and Cartilage of the Femoral Head
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Xu M, Qing M, Peng D
- KMID: 1799516
- Yonsei Med J.
- 2014 Sep;55(5):1447-1449.
- doi: 10.3349/ymj.2014.55.5.1447
Silicosis had been considered for decades as an illness with manifestations of lung fibrosis due to inhalation of overconcentrated SiO2 dust. To the best of our knowledge, studies have yet... -
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- A Two-DNA Methylation Signature to Improve Prognosis Prediction of Clear Cell Renal Cell Carcinoma
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Shi S, Ye S, Wu X, Xu M, Zhuo R, Liao Q, Xi Y
- KMID: 2460217
- Yonsei Med J.
- 2019 Nov;60(11):1013-1020.
- doi: 10.3349/ymj.2019.60.11.1013
PURPOSE: Effective biomarkers and models are needed to improve the prognostic prospects of clear cell renal cell carcinoma (ccRCC). The purpose of this work was to identify DNA methylation biomarkers... -
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- Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4
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Liu Y, Zhang X, Chen S, Wang J, Yu S, Li Y, Xu M, Aboubacar H, Li J, Shan T, Wang J, Cao G
- KMID: 2531376
- Clin Mol Hepatol.
- 2022 Jul;28(3):522-539.
- doi: 10.3350/cmh.2022.0039
Background/Aims: Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the... -
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- Schisantherin B Improves the Pathological Manifestations of Mice Caused by Behavior Desperation in Different Ages-Depression with Cognitive Impairment
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Xu M, Xiao F, Wang M, Yan T, Yang H, Wu B, Bi K, Jia Y
- KMID: 2442007
- Biomol Ther.
- 2019 Feb;27(2):160-167.
- doi: 10.4062/biomolther.2018.074
Depression is a major mood disorder. Abnormal expression of glial glutamate transporter-1 (GLT-1) is associated with depression. Schisantherin B (STB) is one bioactive of lignans isolated from Schisandra chinensis (Turcz.)... -
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- Significance of Preoperative Nerve Reconstruction Using Diffusion Tensor Imaging Tractography for Facial Nerve Protection in Vestibular Schwannoma
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Zhang Y, Ge H, Xu M, Mei W
- KMID: 2539879
- J Korean Neurosurg Soc.
- 2023 Mar;66(2):183-189.
- doi: 10.3340/jkns.2022.0134
Objective : The facial nerve trace on the ipsilateral side of the vestibular schwannoma was reconstructed by diffusion tensor imaging tractography to identify the adjacent relationship between the facial nerve... -
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- Measurement of Intra-Fraction Displacement of the Mediastinal Metastatic Lymph Nodes Using Four-Dimensional CT in Non-Small Cell Lung Cancer
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Wang S, Li J, Zhang Y, Wang W, Li F, Fan T, Xu M, Shao Q
- KMID: 1383853
- Korean J Radiol.
- 2012 Aug;13(4):417-424.
- doi: 10.3348/kjr.2012.13.4.417
OBJECTIVE: To measure the intra-fraction displacements of the mediastinal metastatic lymph nodes by using four-dimensional CT (4D-CT) in non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Twenty-four patients with NSCLC, who... -
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- A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis
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Song S, Zhang Q, Yang H, Guo J, Xu M, Yang N, Yi J, Wang Z, Chen C
- KMID: 2530443
- J Vet Sci.
- 2022 May;23(3):e50.
- doi: 10.4142/jvs.21270
Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components... -
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- Pyrrolidine Dithiocarbamate Inhibits Nuclear Factor kappaB and Toll-Like Receptor 4 Expression in Rats with Acute Necrotizing Pancreatitis
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Xu M, Wang KN, Wu K, Wang XP
- KMID: 2155650
- Gut Liver.
- 2015 May;9(3):411-416.
- doi: 10.5009/gnl14050
BACKGROUND/AIMS: To investigate the expression of Toll-like receptor 4 (TLR4) in the pancreases of rats with acute necrotizing pancreatitis (ANP) and any changes upon treatment with pyrrolidine dithiocarbamate (PDTC), an... -
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- Chronic stress enhances progression of periodontitis via alpha1-adrenergic signaling: a potential target for periodontal disease therapy
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Lu H, Xu M, Wang F, Liu S, Gu J, Lin S
- KMID: 2155383
- Exp Mol Med.
- 2014 Oct;46(10):e118.
- doi: 10.1038/emm.2014.65
This study assessed the roles of chronic stress (CS) in the stimulation of the sympathetic nervous system and explored the underlying mechanisms of periodontitis. Using an animal model of periodontitis... -
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- Chronic stress accelerates ligature-induced periodontitis by suppressing glucocorticoid receptor-α signaling
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Lu H, Xu M, Wang F, Liu S, Gu J, Lin S, Zhao L
- KMID: 2361510
- Exp Mol Med.
- 2016 Mar;48(3):e223.
- doi: 10.1038/emm.2015.127
Periodontitis is a common chronic inflammatory disease. Recent studies have shown that chronic stress (CS) might modulate periodontal disease, but there are few models of CS-induced periodontitis, and the underlying... -
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