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Susac Syndrome With Retinal Vasculitis: A Rare Case Report and Brief Review

Sun T, Qian Y, Wang Z, Xiao Y

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Bilateral Optic Neuropathy as the Prominent Manifestation of Wilson’s Disease

Yang S, Kuang S, Xiao Y, Han X

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Delayed Terminal Ileal Perforation in a Relapsed/Refractory B-Cell Lymphoma Patient with Rapid Remission Following Chimeric Antigen Receptor T-Cell Therapy

Hu Y, Wang J, Pu C, Zhao K, Cui Q, Wei G, Wu W, Xiao L, Xiao Y, Wang J, Wu Z, Huang H

Chimeric antigen receptor T-cell strategy targeting CD19 (CART19) has prominent anti-tumor effect for relapsed/refractory B-cell lymphomas. CART19-associated complications have been gradually recognized, however, late-onset complications have not been extensively studied....
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Novel SPG4 Mutation in a Patient with Sporadic Hereditary Spastic Paraplegia and Elevated Cerebrospinal Fluid Protein

She H, Zheng X, Xiao Y, Mastaglia F, Akkari A, Wu J

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Achalasia: The Current Clinical Dilemma and Possible Pathogenesis

Jia X, Chen S, Zhuang Q, Tan N, Zhang M, Cui Y, Wang J, Xing X, Xiao Y

  • KMID: 2541566
  • J Neurogastroenterol Motil.
  • 2023 Apr;29(2):145-155.
  • doi: 10.5056/jnm22176
Achalasia is a primary esophageal motility disorder manifested by dysphagia and chest pain that impair patients’ quality of life, and it also leads to chronic esophageal inflammation by food retention...
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Erratum: Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

Park S, Yang KM, Park Y, Hong E, Hong CP, Park J, Pang K, Lee J, Park B, Lee S, An H, Kwak MK, Kim J, Kang JM, Kim P, Xiao Y, Nie G, Ooshima A, Kim SJ

The original version of this article contained error in the URL of the SUPPLEMENTARY MATERIALS.
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The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Lv Y, Li B, Han K, Xiao Y, Yu X, Ma Y, Jiao Z, Gao J

Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the...
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Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation

Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L

PURPOSE: The aim of this study was to investigate whether propofol could attenuate hypoxia/reoxygenation-induced apoptosis and autophagy in human renal proximal tubular cells (HK-2) by inhibiting JNK activation. MATERIALS AND METHODS:...
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Seroprevalence and associated risk factors of pseudorabies in Shandong province of China

Hu D, Lv L, Zhang Z, Xiao Y, Liu S

A cross-sectional serological study was conducted in Shandong province of China to determine the seroprevalence and risk factors associated with seropositivity due to pseudorabies virus (PRV) infection in small- and...
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Abnormal Dynamic Functional Connectivity of the Left Rostral Hippocampus in Predicting Antidepressant Efficacy in Major Depressive Disorder

Xue SW, Kuai C, Xiao Y, Zhao L, Lan Z

Objective Some pharmacological treatments are ineffective in parts of patients with major depressive disorder (MDD), hence this needs prediction of effective treatment responses. The study aims to examine the relationship...
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Symptom Severity Related With Contraction Peaks in Patients With Jackhammer Esophagus

Xiao Y, Carlson DA, Pandolfino JE

  • KMID: 2521154
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):540-544.
  • doi: 10.5056/jnm20229
Background/Aims Jackhammer esophagus is an uncommon heterogeneous motility disorder associated with a distal contractile integral > 8000 mmHg · sec · cm. The spectrum of abnormality ranges from a relatively normal...
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Upright Integrated Relaxation Pressure Predicts Symptom Outcome for Esophagogastric Junction Outflow Obstruction

Chen S, Liang M, Tan N, Zhang M, Lin Y, Cao P, Zhuang Q, Xiao Y

  • KMID: 2517530
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):363-369.
  • doi: 10.5056/jnm20106
Background/Aims Esophagogastric junction outflow obstruction (EGJOO) is characterized by elevated integrated relaxation pressure (IRP) and preserved esophageal peristalsis. The clinical significance of EGJOO is uncertain. This study aim to describe the...
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Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study

Xiao Y, Wang B, Chen Y, Chen L, Lou Z, Gong Z

Objective: To identify potential risk factors for cerebrospinal fluid (CSF) leakage after craniovertebral junction (CVJ) anomaly surgery and to provide a reference for clinical practice. Methods: Sixty-six patients who underwent elective...
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Acid Exposure Time > 6% Might Not Improve the Therapeutic Outcome in Chinese Gastroesophageal Reflux Disease Patients

Lin Y, Li Y, Liang M, Tan N, Zhang M, Chen S, Xiao Y

  • KMID: 2510062
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):55-62.
  • doi: 10.5056/jnm19219
Background/Aims There is less acid burden in Chinese gastroesophageal reflux disease (GERD) patients. However, the Lyon consensus proposed a higher threshold of acid exposure time (AET > 6%) for GERD. The...
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Tuber borchii Shapes the Ectomycorrhizosphere Microbial Communities of Corylus avellana

Li X, Zhang X, Yang M, Yan L, Kang Z, Xiao Y, Tang P, Ye L, Zhang B, Zou J, Liu C

In this study, eight-month-old ectomycorrhizae of Tuber borchii with Corylus avellana were synthesized to explore the influence of T. borchii colonization on the soil properties and the microbial communities associated...
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Aberrant Effective Connectivity of the Ventral Putamen in Boys With Attention-Deficit/Hyperactivity Disorder

Lan Z, Sun Y, Zhao L, Xiao Y, Kuai C, Xue SW

Objective The connectivity alterations in the putamen were found in revealing the neural correlates of attention-deficit/hyperactivity disorder (ADHD), but whether the effective connectivity of the putamen is atypical in ADHD...
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Regulatory Mechanism of MicroRNA-145 in the Pathogenesis of Acute Aortic Dissection

Li T, Liu C, Liu L, Xia H, Xiao Y, Wang X, Wang Y

PURPOSE: Previous studies have confirmed that microRNAs play important roles in the pathogenesis of acute aortic dissection (AAD). Here, we aimed to explore the role of miR-145 and its regulatory...
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Clinical response and safety of apatinib monotherapy in recurrent, metastatic cervical cancer after failure of chemotherapy:a retrospective study

Xiao Y, Cheng H, Wang L, Yu X

Objective: To observe the safety and short-term efficacy of apatinib in the treatment of recurrent, metastatic cervical cancer in patients who have already received more than two kinds of comprehensive...
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Esophagogastric Junction Contractility Integral Reflect the Anti-reflux Barrier Dysfunction in Patients with Gastroesophageal Reflux Disease

Xie C, Wang J, Li Y, Tan N, Cui Y, Chen M, Xiao Y

  • KMID: 2367452
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):27-33.
  • doi: 10.5056/jnm16008
BACKGROUND/AIMS: Anti-reflux barrier dysfunction is one of the primary mechanisms in gastroesophageal reflux disease (GERD) pathogenesis. The esophagogastric junction contractile integral (EGJ-CI) is a new metric adopted to evaluate the...
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Longitudinal Assessment of Intravoxel Incoherent Motion Diffusion Weighted Imaging in Evaluating the Radio-sensitivity of Nasopharyngeal Carcinoma Treated with Intensity-Modulated Radiation Therapy

Xiao Y, Chen Y, Chen Y, He Z, Yao Y, Pan J

PURPOSE: Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI)was evaluated regarding its ability to preliminarily predict the short-term treatment response of nasopharyngeal carcinoma (NPC) following intensity-modulated radiation therapy. MATERIALS AND METHODS: IVIM-DWI with...
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