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Cloning of Xenopus laevis TRPV2 by Gene Prediction

Lee JY, Shim WS, Oh U

  • KMID: 1572616
  • Genomics Inform.
  • 2005 Mar;3(1):24-29.
TRPV2 is a non-specific cation channel expressed in sensory neurons, and activated by noxious heat. Particularly, TRPV2 has six transmembrane domains and three ankyrin repeats. TRPV2 has been cloned from...
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Temporal Inhibition of FGF Signal on Endoderm Formation during Early Xenopus laevis Embryogenesis

Cha SW, Park MJ

  • KMID: 2224513
  • Korean J Anat.
  • 2003 Dec;36(6):463-468.
Our previous results showed that FGF signaling, which is important for the mesoderm and neuroectoderm induction, should be blocked for the endoderm formation in Xenopus. Here, Xenopus embryos were collected...
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Block of ATP-sensitive K+ channels expressed in Xenopus oocytes by dimethyl sulfoxide

Park JB, Chae SW

  • KMID: 2285236
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):157-163.
The effects of dimethyl sulfoxide (DMSO) were studied in two groups of Xenopus oocytes, one expressing ATP sensitive K+ (KATP) channel comprised of sulfonylurea receptor SUR1 and inwardly rectifying K+ channel subunit Kir6.2,...
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Na, K-ATPase beta2 isoform (atp1b2) expressed in the retina of Xenopus

Rahman MM, Park BY

The ubiquitous Na, K-ATPase is a membrane-bound ion pump located in the plasma membrane in all animal cells and plays an essential role in a variety of cellular functions. Studies...
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Osteocalcin Expression and Mineralization in Developing Tooth of Xenopus laevis

Park JH, Kwon KT, Park BK, Lee YH

Osteocalcin (OC) is the most abundant noncollagenous protein of extracellular matrix in the bone. In an OC deficient mouse, bone formation rates are increased in cancellous and cortical bones. OC...
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xCITED2 Induces Neural Genes in Animal Cap Explants of Xenopus Embryos

Yoon J, Kim JH, Lee OJ, Yu SB, Kim JI, Kim SC, Park JB, Lee JY, Kim J

Neural tissue is arisen from presumptive ectoderm via inhibition of bone morphogenetic protein (BMP) signaling during Xenopus early development. Previous studies demonstrate that ectopic expression of dominant negative BMP4 receptor...
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Spatiotemporal regulation of fibroblast growth factor signal blocking for endoderm formation in Xenopus laevis

Cha SW, Lee JW, Hwang YS, Chae JP, Park KM, Cho HJ, Kim DS, Bae YC, Park MJ

We have previously shown that the inhibition of fibroblast growth factor (FGF) signaling induced endodermal gene expression in the animal cap and caused the expansion of the endodermal mass in...
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Expression analysis of ciliary rootlet coiled coil protein mRNA during Xenopus development

Rahman MM, Kim IS, Ahn DC, Cho HS, Kim WI, Kim B, Shin GW, Kwon J, Akanda MR, Park BY

Ciliary rootlet coiled coil protein (CROCC), the structural component that originates from the basal body at the proximal end of the ciliary rootlet, plays a crucial role in maintaining the...
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Effects of Halothane, Enflurane or Isoflurane on the m1 or m3 Muscarinic Receptor Expressed in Xenopus Oocytes

Do SH

BACKGROUND: Muscarinic receptors are distributed abundantly in the central nervous system and peripheral visceral organs, and have a close relationship with anesthesia. We investigated the effects of halothane, enflurane...
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Effect of ginsenosides on the desflurane modulation in the recombinant serotonin type 3A receptor expressed in Xenopus laevis oocytes

Choi SH, Kim MK, Koo BN, Min KT

BACKGROUND: Postoperative nausea and vomiting (PONV) is the most frequent and discomforting side effect following general anesthesia. Most volatile anesthetics have a potent effect on serotonin (5-hydroxydtryptamine, 5-HT) type 3...
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Effect of Pdx1 Expression after Sox9 Depletion in the Early Pancreatic Development in African Clawed Frog (Xenopus laevis)

Park BY, Li LG, Choi EH, Jung MY, Kwon KT, Jeong YH, Kim JY, Kim IS, Park BK, Lee YH

  • KMID: 2092885
  • Korean J Anat.
  • 2007 Mar;40(1):1-10.
The pancreas is a mixed exocrine and endocrine gland involved in the control of many homeostatic functions.During embryogenesis,the pancreas arises from dorsal and ventral evaginations of the foregut,which subse- quently...
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Quercetin Inhibits alpha3beta4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY

  • KMID: 2389104
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):17-22.
Quercetin mainly exists in the skin of colored fruits and vegetables as one of flavonoids. Recent studies show that quercetin, like other flavonoids, has diverse pharmacological actions. However, relatively little...
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Expression and localization of Rdd proteins in Xenopus embryo

Lim JC, Kurihara S, Tamaki R, Mashima Y, Maeno M

The previous study has shown that repeated D domain-like (Rdd) proteins, a group of novel secretory proteins consisting of repeated domains of a cysteine-rich sequence, are involved in the process...
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Effects of clonidine on the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes

Woo JH, Han JI, Baik HJ, Lee H

BACKGROUND: Clonidine has been shown to be a potent neuroprotectant by acting at alpha2 receptors on glutamatergic neurons to inhibit the release of glutamate. The aim of this study is...
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Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development

Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J

  • KMID: 1123768
  • Exp Mol Med.
  • 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be...
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Block of hERG K+ Channel by Classic Histamine H1 Receptor Antagonist Chlorpheniramine

Hong HK, Jo SH

Chlorpheniramine is a potent first-generation histamine H1 receptor antagonist that can increase action potential duration and induce QT prolongation in several animal models. Since block of cardiac human ether-a-go-go-related gene...
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Remifentanil increases the activity of the glutamate transporter, EAAC1, expressed in Xenopus oocytes

Ryu J, Do SH, Lee N

  • KMID: 2046779
  • Anesth Pain Med.
  • 2008 Oct;3(4):264-269.
BACKGROUND: Remifentanil has gained wide clinical acceptance during anesthesia due to its short context-sensitive half time and organ-independent metabolism. However, its mechanism as an anesthetic remains unclear. Glutamate transporters may...
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Resveratrol Inhibits GABAC rho Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Choi SH, Hwang SH, Kim HJ, Lee JH, Nah SY

Resveratrol is a phytoalexin found in grapes, red wine, and berries. Resveratrol has been known to have many beneficial health effects, such as anti-cancer, neuroprotective, anti-inflammatory, and life-prolonging effects. However,...
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Transcriptional Regulation of the Xbr-1a/Xvent-2 Gene by BMP-4 Signaling during Xenopus Embryonic Development

Kim JB, Lee HS, Roh DH, Hwang YS, Xu RH, Kung HF, Bae YC, Park MJ

  • KMID: 2224548
  • Korean J Anat.
  • 2000 Oct;33(5):595-608.
BMP-4 signaling is mediated through Smad proteins which may translocate to the nucleus to activate transcription. Little is known about how BMP-4 signaling regulates the transcription of its target genes,...
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Isolation of Early Neurogenesis Genes with Xenopus cDNA Microarray

Yu SB, Lee OJ, Park YJ, Lee SY, Lee SH, Yoon J, Hwang YS, Kim JI, Lee JY, Park JB, Kim SC, Kim J

Neurogenesis is the process that develops neuroectoderm from ectoderm. Bone morphogenetic protein (BMP) inhibition in ectodermal cells is necessary and sufficient for neurogenesis in Xenopus embryos. To isolate genes involved...
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