- Green tea polyphenol (–)-epigallocatechin-3-gallate prevents ultraviolet-induced apoptosis in PC12 cells
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Woo SM, Kim YJ, Cai B, Park SY, Kim Y, Kim OJ, Kang IC, Kim WJ, Jung JY
- KMID: 2510198
- Int J Oral Biol.
- 2020 Dec;45(4):179-189.
- doi: 10.11620/IJOB.2020.45.4.179
Green tea polyphenol (–)-epigallocatechin-3-gallate (EGCG) is a potent antioxidant with protective effects against neurotoxicity. However, it is currently unclear whether EGCG protects neuronal cells against radiation-induced damage. Therefore, the objective... -
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- The Histone Lysine-specific Demethylase 1 Inhibitor, SP2509 Exerts Cytotoxic Effects against Renal Cancer Cells through Downregulation of Bcl-2 and Mcl-1
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Wu K, Woo SM, Kwon TK
- KMID: 2503564
- J Cancer Prev.
- 2020 Jun;25(2):79-86.
- doi: 10.15430/JCP.2020.25.2.79
Lysine-specific histone demethylase 1 (LSD1), also known as KDM1A, can remove the methyl group from lysine 4 and 9 at histone H3, which regulates transcriptional suppression and activation. Recently, high... -
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- Comprehensive Cancer Panel Sequencing Defines Genetic Diversity and Changes in the Mutational Characteristics of Pancreatic Cancer Patients Receiving Neoadjuvant Treatment
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Yoon KA, Woo SM, Kim YH, Kong SY, Lee MK, Han SS, Kim TH, Lee WJ, Park SJ
- KMID: 2464315
- Gut Liver.
- 2019 Nov;13(6):683-689.
- doi: 10.5009/gnl18355
BACKGROUND/AIMS: Pancreatic ductal adenocarcinoma (PDA) is associated with an extremely poor prognosis. This study assessed the genetic diversity among patients with PDA and compared their mutational profiles before and after... -
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- Somatic Mutations from Whole Exome Sequencing Analysis of the Patients with Biliary Tract Cancer
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Yoon KA, Woo SM, Kim YH, Kong SY, Han SS, Park SJ, Lee WJ
- KMID: 2439225
- Genomics Inform.
- 2018 Dec;16(4):e35.
- doi: 10.5808/GI.2018.16.4.e35
Biliary tract cancer (BTC) is a rare cancer and is associated with a poor prognosis. To understand the genetic characteristics of BTC, we analyzed whole-exome sequencing data and identified somatic... -
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- Prospective Multicenter Study of the Challenges Inherent in Using Large Cell-Type Stents for Bilateral Stent-in-Stent Placement in Patients with Inoperable Malignant Hilar Biliary Obstruction
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Yang MJ, Kim JH, Hwang JC, Yoo BM, Lee SH, Ryu JK, Kim YT, Woo SM, Lee WJ, Jeong S, Lee DH
- KMID: 2427463
- Gut Liver.
- 2018 Nov;12(6):722-727.
- doi: 10.5009/gnl17468
BACKGROUND/AIMS: Although endoscopic bilateral stent-in-stent placement is challenging, many recent studies have reported promising outcomes regarding technical success and endoscopic re-intervention. This study aimed to evaluate the technical accessibility of... -
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- Proximal Resection Margins: More Prognostic than Distal Resection Margins in Patients Undergoing Hilar Cholangiocarcinoma Resection
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Yoo T, Park SJ, Han SS, Kim SH, Lee SD, Kim TH, Lee SA, Woo SM, Lee WJ, Hong EK
- KMID: 2424783
- Cancer Res Treat.
- 2018 Oct;50(4):1106-1113.
- doi: 10.4143/crt.2017.320
PURPOSE: Even though the therapeutic gold standard of hilar cholangiocarcinoma (HCCA) resection is cancer-free resection margin (RM), surgical treatment still remains challenging. This study evaluated the prognostic significance of RM... -
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- Effectiveness and feasibility of concurrent chemoradiotherapy using simultaneous integrated boost-intensity modulated radiotherapy with and without induction chemotherapy for locally advanced pancreatic cancer
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Oh ES, Kim TH, Woo SM, Lee WJ, Lee JH, Youn SH, Han SS, Park SJ, Kim DY
- KMID: 2426296
- Radiat Oncol J.
- 2018 Sep;36(3):200-209.
- doi: 10.3857/roj.2018.00073
PURPOSE: To evaluate the effectiveness and feasibility of chemoradiotherapy (CRT) using simultaneous integrated boost-intensity modulated radiotherapy (SIB-IMRT) in locally advanced pancreatic cancer (LAPC) patients. MATERIALS AND METHODS: Between January 2011 and... -
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- Profiling of Serum Metabolites Using MALDI-TOF and Triple-TOF Mass Spectrometry to Develop a Screen for Ovarian Cancer
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Lee JH, Kim YH, Kim KH, Cho JY, Woo SM, Yoo BC, Kim SC
- KMID: 2417877
- Cancer Res Treat.
- 2018 Jul;50(3):883-893.
- doi: 10.4143/crt.2017.275
PURPOSE: We sought to develop a matrix assisted laser desorption ionization-time of flight (MALDI-TOF)-based, ovarian cancer (OVC), low-mass-ion discriminant equation (LOME) and to evaluate a possible supportive role for triple-TOF... -
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- Novel non-apoptotic cell death: ferroptosis
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Woo SM, Kwon TK
- KMID: 2400352
- Yeungnam Univ J Med.
- 2017 Dec;34(2):174-181.
- doi: 10.12701/yujm.2017.34.2.174
Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic... -
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- Induction Chemotherapy with Gemcitabine and Cisplatin Followed by Simultaneous Integrated Boost–Intensity Modulated Radiotherapy with Concurrent Gemcitabine for Locally Advanced Unresectable Pancreatic Cancer: Results from a Feasibility Study
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Woo SM, Kim MK, Joo J, Yoon KA, Park B, Park SJ, Han SS, Lee JH, Hong EK, Kim YH, Moon H, Kong SY, Kim TH, Lee WJ
- KMID: 2394821
- Cancer Res Treat.
- 2017 Oct;49(4):1022-1032.
- doi: 10.4143/crt.2016.495
PURPOSE: This study assessed the feasibility and compliance of induction chemotherapy with gemcitabine and cisplatin followed by simultaneous integrated boost–intensity modulated radiotherapy (SIB-IMRT) with concurrent gemcitabine in patients with locally... -
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- Effect of Capecitabine plus Oxaliplatin for Advanced Adenocarcinoma of Ampulla of Vater
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Lee JH, Kim KH, Woo SM, Park SJ, Han SS, Hong EK, Koh YH, Lee JH, Lee WJ
- KMID: 2448607
- Korean J Pancreas Biliary Tract.
- 2017 Jul;22(3):127-133.
- doi: 10.15279/kpba.2017.22.3.127
BACKGROUND/AIM: Adenocarcinoma arising from the ampulla of Vater is a rare disease and has limited data regarding outcome of palliative chemotherapy. We investigated the efficacy and safety of capecitabine plus... -
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- Chemotherapy for Biliary Tract Cancer
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Woo SM
- KMID: 2383410
- Korean J Gastroenterol.
- 2017 Mar;69(3):172-176.
- doi: 10.4166/kjg.2017.69.3.172
The term of biliary tract cancer (BTC) refers to all tumors that arise from the biliary tract or the biliary drainage system, including the intra- and extra-hepatic bile ducts as... -
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- Adult intussusception caused by inverted Meckel's diverticulum treated with operation
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Lee SY, Jeong JY, Hong SH, Woo SM, Lee SH, You HJ, Kim DW
- KMID: 2366122
- Yeungnam Univ J Med.
- 2016 Dec;33(2):116-119.
- doi: 10.12701/yujm.2016.33.2.116
Intussusception is a serious disease where part of the intestine slides into an adjacent part of the intestine. Adult intussusception is mainly due to benign or malignant neoplasm. Therefore, in... -
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- Myelomatous Pleural Effusion with Elevated ADA Activity
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Moon HJ, Shin DY, Kim HR, Park YW, Woo SM, Cha JH, Han KH
- KMID: 2361441
- Korean J Med.
- 2016 Dec;91(3):316-320.
- doi: 10.3904/kjm.2016.91.3.316
Multiple myeloma is a plasma cell neoplasm mainly involving the bone marrow and skeletal system. Myelomatous pleural effusion is rare, accounting for less than 1%. In cases with high adenosine... -
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- Role of Neoadjuvant Therapy for Borderline Resectable or Locally Advanced Pancreatic Cancer
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Lee WJ, Woo SM
- KMID: 2448525
- Korean J Pancreas Biliary Tract.
- 2016 Jul;21(3):117-127.
- doi: 10.15279/kpba.2016.21.3.117
Surgical resection offers the only chance of cure for nonmetastatic exocrine pancreatic cancer. However, only 15 to 20 percent of patients have potentially resectable disease at diagnosis; approximately 40 percent... -
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- A Case of Curative Resection of Advanced Combined Hepatocellular-cholangiocarcinoma after Neoadjuvant Chemotherapy
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Choi JE, Kim KH, Kim SA, Lee JH, Woo SM, Park SJ, Hong EK, Lee WJ
- KMID: 2448522
- Korean J Pancreas Biliary Tract.
- 2016 Apr;21(2):101-106.
- doi: 10.15279/kpba.2016.21.2.101
Combined hepatocellular-cholangiocarcinoma (HCC-CC) is a primary liver cancer with histopathologic features of both hepatocelluar carcinoma and cholangiocarcinoma. As combined HCC-CC has been associated with poor outcomes, accurate diagnosis and proper... -
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- Ampulla of Vater Adenomyoma with Dilatations of Biliary and Pancreatic Duct
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Kim SA, Woo SM, Hong EK, Han SS, Park SJ, Koh YH, Lee JH, Lee WJ
- KMID: 2448509
- Korean J Pancreas Biliary Tract.
- 2016 Jan;21(1):29-33.
- doi: 10.15279/kpba.2016.21.1.29
Adenomyoma is a non-neoplastic lesion that frequently occurs in the gallbladder, but it's rarely found at the ampulla of Vater. When it develops at the ampulla of Vater, it may... -
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- A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient
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Woo SM, Hong SH, Lee SY, Lee SH, Lee DK, Yang SJ
- KMID: 2149294
- J Korean Diabetes.
- 2015 Sep;16(3):225-229.
- doi: 10.4093/jkd.2015.16.3.225
Insulin deficiency due to destruction of pancreatic beta-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining "fulminant type 1... -
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- Phase I Dose-Escalation Study of Proton Beam Therapy for Inoperable Hepatocellular Carcinoma
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Kim TH, Park JW, Kim YJ, Kim BH, Woo SM, Moon SH, Kim SS, Koh YH, Lee WJ, Park SJ, Kim JY, Kim DY, Kim CM
- KMID: 2380388
- Cancer Res Treat.
- 2015 Jan;47(1):34-45.
- doi: 10.4143/crt.2013.218
PURPOSE: The purpose of this study is to determine the optimal dose of proton beam therapy (PBT) in hepatocellular carcinoma (HCC) patients. MATERIALS AND METHODS: Inoperable HCC patients who had naive,... -
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- Quality of Life in Korean Patients with Obstructive Sleep Apnea
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Woo SM, Jeon JY, Kim DE, Hwang SH, Cho YW
- KMID: 2343544
- J Korean Neurol Assoc.
- 2014 Nov;32(4):240-245.
- doi: 10.0000/jkna.2014.32.4.240
BACKGROUND: Obstructive sleep apnea (OSA) is a common disease, but there are few studies about the quality of life (QOL) of Korean patients with OSA. The aims of the present... -
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