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Triple High Dose Chemotherapy Followed by Autologous Stem Cell Transplantation for Pediatric Neuroblastoma

Woo MJ, Choi SR, Kim BS, Kim HS, Won SC, Lyu CJ

  • KMID: 1448319
  • Clin Pediatr Hematol Oncol.
  • 2011 Oct;18(2):97-102.
BACKGROUND: High-risk group neuroblastoma (HRNB) is one of the most incurable diseases in pediatric oncology field. This report explores the effectiveness, safety and feasibility of triple high dose chemotherapy followed...
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Inflammatory Myofibroblastic Tumor in a 3 Months Old Infant

Woo MJ, Yu HY, Kim BS, Won SC, Lyu CJ, Oh JT

  • KMID: 2168937
  • Clin Pediatr Hematol Oncol.
  • 2011 Apr;18(1):62-65.
Benign intestinal tumors are rare in infancy, however the authors describe an inflammatory myofibroblastic tumor (IMT) of the mesentery in a 3-month-old infant who was diagnosed incidentally. During operation, huge...
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A Case of Refractory Iron Deficiency Anemia as a Manifestation of Cavernous Hemangioma of the Small Intestine

Chae HW, Won SC, Han JW, Kim HK, Oh JT, Lyu CJ

  • KMID: 2279857
  • Clin Pediatr Hematol Oncol.
  • 2007 Apr;14(1):64-67.
Iron deficiency anemia is the most common hematologic disease of infancy and childhood. Iron deficiency anemia caused by hemangioma of the small intestine is uncommon. We report a case of...
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A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor

Kwon BC, Shin KM, Won SC, Lyu CJ, Yang CH, Kim HO

  • KMID: 2335659
  • J Korean Pediatr Soc.
  • 2002 Jul;45(7):912-916.
Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15-...
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A Case of Cystic Partially Differentiated Nephroblastoma

Baek DW, Kim HS, Kwon SY, Kim BS, Choi SY, Cho NH, Won SC, Lyu CJ

  • KMID: 2168954
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):27-31.
Cystic partially differentiated nephroblastoma is a rare renal mass in children. Since its clinical characteristics and radiologic findings are very similar to those of cystic Wilms tumor and cystic...
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A Case of Wilms Tumor with Thrombi which Invaded the Right Ventricule

Uhm JH, Won SC, Lyu CJ, Yang CH, Kim BS, Hwang EH, Park YH, Seo CO

  • KMID: 2335605
  • J Korean Pediatr Soc.
  • 2002 Mar;45(3):390-394.
Wilms tumor is the second most common malignant retroperitoneal tumor. Inferior vena cava and right atrial involvement is found in about 4-10% and 0.5-3% of cases, respectively. But, right ventricular...
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A Case of Autologous Cord Blood Stem Cell Transplantationin Stage IV Neuroblastoma

Chae JH, Kim HS, Kwon SY, Won SC, Kim BS, Choi SY, Lyu CJ

  • KMID: 2168953
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):21-26.
Since High dose chemotherapy (HDCT) with autologous hematopoietic stem cell (HSC) rescue has been reported to be the most effective current treatment modality in advanced and refractory neuroblastoma, various types...
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Therapeutic Leukapheresis for Acute Lymphoblastic Leukemia with Severe Hyperleukocytosis in a Six-Week-Old Infant (4.7 kg)

Byun JY, Shin KM, Won SC, Lyu CJ, Lim HS, Kim HO

  • KMID: 1917300
  • Korean J Pediatr Hematol Oncol.
  • 2002 Oct;9(2):250-254.
We report a 4.7 kg infant who received a therapeutic leukapheresis as an immediate treatment for acute lymphoblastic leukemia with severe hyperleukocytosis. By decreasing the number of circulating white...
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Polymorphisms within Glutathione S-transferase Genes in Childhood Acute Lymphoblastic Leukemia

Won SC, Han JW, Lyu CJ

  • KMID: 2278312
  • Korean J Pediatr Hematol Oncol.
  • 2004 Oct;11(2):171-178.
PURPOSE: Glutathione S-transferases (GSTs) are polymorphic genes. Absence of enzyme activity due to homozygous or heterozygous deletion of the gene is associated with reduced detoxification of carcinogens and potentially increasing...
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A Case of Indeterminate Cell Histiocytosis in an Infant

Kim NK, Choi SY, Lee KG, Kwon SY, Han JW, Won SC, Lyu CJ

  • KMID: 2279923
  • Clin Pediatr Hematol Oncol.
  • 2007 Oct;14(2):221-225.
Indeterminate cell histiocytosis is a rare disease of predominant cells having features that resemble both Langerhans cells and macrophages. The cells have greater pleomorphism with polyobated nuclei and these cells...
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A Case of Subcutaneous Panniculitis-like T Cell Lymphoma in Childhood

Choi YS, Shin KM, Won SC, Lyu CJ, Yang CH, Kim BS, Kim MK

  • KMID: 2207208
  • J Korean Pediatr Soc.
  • 2002 Aug;45(8):1028-1032.
Subcutaneous pannicultis-like T cell lymphoma is a rare cutaneous T cell lymphoma. It presents with multiple subcutaneous nodules or plaques involving the extremities or trunk, and with constitutional symptoms that...
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Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients

Won SC, Han DK, Seo JJ, Chung NG, Park SK, Park KB, Kook H, Lyu CJ

BACKGROUND: Iron overload is a predictable and life-threatening complication in patients dependent on the regular transfusion of RBCs. The aims of this study were to investigate the efficacy and safety...
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Late Effect of Pediatric Cancer Therapy on Thyroid Function

Kim HS, Han JW, Kwon S, Won SC, Lyu CJ

  • KMID: 1483075
  • Clin Pediatr Hematol Oncol.
  • 2008 Apr;15(1):10-16.
Purpose: According to advances in childhood cancer therapy, survival outcomes are markedly improved during the past few decades. On the other hand, late effects of childhood cancer survivors are nowadays...
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A Comparative Analysis between Flow Cytometry and RT-PCR Methods for the Detection of Minimal Residual Disease in Neuroblastoma

Kwon BC, Kim KS, Won SC, Oh SH, Lyu CJ, Yang CH

  • KMID: 1917293
  • Korean J Pediatr Hematol Oncol.
  • 2002 Oct;9(2):203-210.
PURPOSE: A sensitive assay to detect minimal residual disease in neuroblastoma is necessary for accurate assessment of disease status and optimal treatment. In this study, we compared the usefulness of...
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Experience of Childhood Non-Hodgkin Lymphoma with Central Nervous System Involvement at Diagnosis

Choi SY, Kim NK, Kwon SY, Han JW, Won SC, Lyu CJ

  • KMID: 2279916
  • Clin Pediatr Hematol Oncol.
  • 2007 Oct;14(2):183-191.
PURPOSE: Lymphoma is the third most common cancer among children and non-Hodgkin lymphoma accounts for approximately 90% of all lymphomas in children and adolescents in Korea. Central nervous system involvement...
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Patterns of Relapse and Survival for Neuroblastoma

Won SC, Lyu CJ, Cho HS, Yang CH, Kim BS

  • KMID: 2072500
  • Korean J Pediatr Hematol Oncol.
  • 2001 Oct;8(2):250-255.
PURPOSE: Nowadays, survival of neuroblastoma patients has improved by high dose chemotherapy followed by autologous peripheral blood stem cell transplantation (PBSCT). But, many of these patients experienced treatment failure,...
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Influence of Prognostic Factors on Survival Rate of Medulloblastoma Patient with Chemotherapy

Shin KM, Choi SY, Won SC, Yang CH, Lyu CJ, Suh CO, Choi JU, Kim BS

  • KMID: 2335709
  • J Korean Pediatr Soc.
  • 2003 Feb;46(2):178-182.
PURPOSE: Brain tumors are the second most common tumor in childhood, and medulloblastomas comprise 15-25% of brain tumors. The well known prognostic factors are age at diagnosis, stage of disease,...
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A Clinical Study on Childhood Hemolytic Anemia According to Etiological Classification

Kwon HS, Kang JC, Won SC, Oh SH, Lyu CJ

  • KMID: 1607034
  • J Korean Pediatr Soc.
  • 2003 Sep;46(9):883-888.
PURPOSE: The etiology of hemolytic anemia can be classified as either cellular or extracellular defects of red blood cells. The aim of this study was to investigate the clinical and...
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Comparative Results of Autologous Hematopoietic Stem Cell Transplantation in Childhood Acute Myeloid Leukemia Patients with Continuous Complete Remission during Consolidation Chemotherapy

Choi SY, Kim NK, Kwon SY, Han JW, Won SC, Lyu CJ

  • KMID: 2279913
  • Clin Pediatr Hematol Oncol.
  • 2007 Oct;14(2):159-166.
PURPOSE: In many studies, allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is the most effective treatment of acute myeloid leukemia (AML). Autologous hematopoietic stem cell transplantation (Auto-HSCT) is another choice of...
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Clinical Role of Bone Marrow Angiogenesis in Childhood Acute Lymphocytic Leukemia

Lyu CJ, Rha SY, Won SC

PURPOSE: Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are associated with increased angiogenesis, growth, and metastasis in solid tumors. But, until today, the importance of theses...
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