- Immunohistochemical study of caveolin-1 and -2 in the rat retina
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Kim H, Lee T, Lee J, Ahn M, Moon C, Wie MB, Shin T
- KMID: 1059192
- J Vet Sci.
- 2006 Jun;7(2):101-104.
- doi: 10.4142/jvs.2006.7.2.101
The expression of caveolin-1 and -2 in the retina was examined; Western blot analysis showed that both were present. Immunohistochemistry indicated that caveolin-1 was expressed in the majority of retinal layers, including the ganglion... -
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- Melatonin ameliorates autoimmune encephalomyelitis through suppression of intercellular adhesion molecule-1
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Kang JC, Ahn M, Kim YS, Moon C, Lee Y, Wie MB, Lee YJ, Shin T
- KMID: 1103513
- J Vet Sci.
- 2001 Aug;2(2):85-89.
Melatonin (N-acetyl-5-methoxytryptamine), a pineal neurohormone, is a hydroxyl radical scavenger and antioxidant, and plays an important role in the immune system. We studied the effect of exogenous melatonin on the... -
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- Neuroprotective effects of resveratrol on 6-hydroxydopamine-induced damage of SH-SY5Y cell line
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Chang GC, Kim HC, Wie MB
- KMID: 1700783
- Korean J Vet Res.
- 2014 Mar;54(1):1-6.
Parkinson's disease is known to exhibit progressive degeneration of the dopaminergic neurons in the substantia nigra via inhibition of glutathione metabolism. It is well known that 6-Hydroxydopamine (6-OHDA) induces Parkinson's... -
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- Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis
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Kim S, Moon C, Wie MB, Kim H, Tanuma N, Matsumoto , Shin T
- KMID: 1103469
- J Vet Sci.
- 2000 Jun;1(1):11-17.
To elucidate the role of nitric oxide synthase (NOS) in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), we analyzed the expression of constitutive neuronal NOS (nNOS), endothelial NOS (eNOS), and... -
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- Benefits of hesperidin in central nervous system disorders: a review
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Kim J, Wie MB, Ahn M, Tanaka A, Matsuda H, Shin T
- KMID: 2466688
- Anat Cell Biol.
- 2019 Dec;52(4):369-377.
- doi: 10.5115/acb.19.119
Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy individuals. Hesperidin, which is an abundant... -
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- Fucoidan attenuates 6-hydroxydopamine-induced neurotoxicity by exerting anti-oxidative and anti-apoptotic actions in SH-SY5Y cells
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Kim MH, Namgoong H, Jung BD, Kwon MS, Choi YS, Shin T, Kim HC, Wie MB
- KMID: 2376872
- Korean J Vet Res.
- 2017 Mar;57(1):1-7.
- doi: 10.14405/kjvr.2017.57.1.1
Parkinson's disease (PD) is an irreversible neurological disorder with related locomotor dysfunction and is haracterized by the selective loss of nigral neurons. PD can be experimentally induced by 6-hydroxydopamine (6-OHDA).... -
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- Esculetin inhibits N-methyl-D-aspartate neurotoxicity via glutathione preservation in primary cortical cultures
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Lee CR, Shin EJ, Kim HC, Choi YS, Shin T, Wie MB
- KMID: 1850055
- Lab Anim Res.
- 2011 Sep;27(3):259-263.
- doi: 10.5625/lar.2011.27.3.259
Recently, loss of endogenous glutathione during N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxic injury, and the resultant overproduction of reactive oxygen species (ROS) through an arachidonic acid cascade process in brain, have been... -
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