- Type of Rectal Barostat Protocol Affects Classification of Hypersensitivity and Prediction of Symptom Severity in Irritable Bowel Syndrome
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Josefsson A, Törnblom H, Simrén M
- KMID: 2534322
- J Neurogastroenterol Motil.
- 2022 Oct;28(4):630-641.
- doi: 10.5056/jnm21214
Background/Aims Visceral hypersensitivity is an important pathophysiologic mechanism in irritable bowel syndrome (IBS). We compared 2 barostat distension protocols and their ability to distinguish between IBS patients and healthy controls, identify... -
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- Vagal Transient Receptor Potential Ankyrin 1 Mediates Stress-exacerbated Visceral Mechanonociception After Antral Cold Exposure
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Chen X, Luo Q, Yan X, Li W, Chen S
- KMID: 2454643
- J Neurogastroenterol Motil.
- 2019 Jul;25(3):442-460.
- doi: 10.5056/jnm19014
BACKGROUND/AIMS: Abdominal pain can be evoked or exacerbated after gastrointestinal cold stimulation in some patients with diarrhea-predominant irritable bowel syndrome (IBS-D), indicating a low temperature-induced sensitization of visceral perception. We... -
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- Understanding Neurogastroenterology From Neuroimaging Perspective: A Comprehensive Review of Functional and Structural Brain Imaging in Functional Gastrointestinal Disorders
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Kano M, Dupont P, Aziz Q, Fukudo S
- KMID: 2422842
- J Neurogastroenterol Motil.
- 2018 Oct;24(4):512-527.
- doi: 10.5056/jnm18072
This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses... -
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- Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation
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Ait-Belgnaoui A, Payard I, Rolland C, Harkat C, Braniste V, Théodorou V, Tompkins T
- KMID: 2417281
- J Neurogastroenterol Motil.
- 2018 Jan;24(1):138-146.
- doi: 10.5056/jnm16167
BACKGROUND/AIMS: Visceral pain and hypothalamic-pituitary-adrenal axis (HPA) dysregulation is a common characteristic in irritable bowel syndrome (IBS) patients. Previously, we reported that a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium... -
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- Mechanisms of Stress-induced Visceral Pain
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Greenwood-Van Meerveld B, Johnson AC
- KMID: 2417268
- J Neurogastroenterol Motil.
- 2018 Jan;24(1):7-18.
- doi: 10.5056/jnm17137
Evidence suggests that long-term stress facilitates visceral pain through sensitization of pain pathways and promotes chronic visceral pain disorders such as the irritable bowel syndrome (IBS). This review will describe... -
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- Protein Kinase C Mediates the Corticosterone-induced Sensitization of Dorsal Root Ganglion Neurons Innervating the Rat Stomach
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Li M, Xue L, Zhu HY, Wang H, Xu X, Zhang PA, Wu G, Xu GY
- KMID: 2387838
- J Neurogastroenterol Motil.
- 2017 Jul;23(3):464-476.
- doi: 10.5056/jnm16161
BACKGROUND/AIMS: Gastric hypersensitivity contributes to abdominal pain in patients with functional dyspepsia. Recent studies showed that hormones induced by stress are correlated with visceral hypersensitivity. However, the precise mechanisms underlying... -
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- Dai-Kenchu-To, a Herbal Medicine, Attenuates Colorectal Distention-induced Visceromotor Responses in Rats
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Nakaya K, Nagura Y, Hasegawa R, Ito H, Fukudo S
- KMID: 2433462
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):686-693.
- doi: 10.5056/jnm15190
BACKGROUND/AIMS: Dai-kenchu-to (DKT), a traditional Japanese herbal medicine, is known to increase gastrointestinal motility and improve ileal function. We tested our hypotheses that (1) pretreatment with DKT would block the... -
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- Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside
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Zhang L, Song J, Hou X
- KMID: 2203567
- J Neurogastroenterol Motil.
- 2016 Apr;22(2):181-192.
- doi: 10.5056/jnm15137
Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder since it lacks demonstrable pathological abnormalities. However, in recent years, low grade inflammatory infiltration, often rich in mast cells,... -
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- The relationship of preoperative anxiety with failure of extension of epidural analgesia for cesarean section
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Yoon HJ, Park SI
- KMID: 2148012
- Anesth Pain Med.
- 2015 Oct;10(4):271-277.
- doi: 10.17085/apm.2015.10.4.271
BACKGROUND: Patients anesthetized by extension of epidural analgesia during labor frequently experience intraoperative visceral pain during cesarean section. Visceral pain is known to be related to anxiety. We evaluated pain... -
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- Visceral Pain and Gastrointestinal Microbiome
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Chichlowski M, Rudolph C
- KMID: 2381249
- J Neurogastroenterol Motil.
- 2015 Apr;21(2):172-181.
- doi: 10.5056/jnm15025
A complex set of interactions between the microbiome, gut and brain modulate responses to visceral pain. These interactions occur at the level of the gastrointestinal mucosa, and via local neural,... -
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- Role of MicroRNA in Visceral Pain
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Zhang J, Banerjee B
- KMID: 2381248
- J Neurogastroenterol Motil.
- 2015 Apr;21(2):159-171.
- doi: 10.5056/jnm15027
The long-lasting nociceptive transmission under various visceral pain conditions involves transcriptional and/or translational alteration in neurotransmitter and receptor expression as well as modification of neuronal function, morphology and synaptic connections.... -
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- Role of Principal Ionotropic and Metabotropic Receptors in Visceral Pain
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Kannampalli P, Sengupta J
- KMID: 2381247
- J Neurogastroenterol Motil.
- 2015 Apr;21(2):147-158.
- doi: 10.5056/jnm15026
Visceral pain is the most common form of pain caused by varied diseases and a major reason for patients to seek medical consultation. It also leads to a significant economic... -
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- Alternative Method of Retrocrural Approach during Celiac Plexus Block Using a Bent Tip Needle
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An JW, Choi EK, Park CH, Choi JB, Ko DK, Lee YW
- KMID: 2278270
- Korean J Pain.
- 2015 Apr;28(2):109-115.
- doi: 10.3344/kjp.2015.28.2.109
BACKGROUND: This study sought to determine safe ranges of oblique angle, skin entry point and needle length by reviewing computed tomography (CT) scans and to evaluate the usefulness of a... -
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- Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia
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Tache Y, Million M
- KMID: 2381228
- J Neurogastroenterol Motil.
- 2015 Jan;21(1):8-24.
- doi: 10.5056/jnm14162
The corticotropin-releasing factor (CRF) signaling systems encompass CRF and the structurally related peptide urocortin (Ucn) 1, 2, and 3 along with 2 G-protein coupled receptors, CRF1 and CRF2. CRF binds... -
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- Spinal Cord Stimulation for Intractable Visceral Pain Due to Sphincter of Oddi Dysfunction
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Lee KH, Lee SE, Jung JW, Jeon SY
- KMID: 2278254
- Korean J Pain.
- 2015 Jan;28(1):57-60.
- doi: 10.3344/kjp.2015.28.1.57
Sphincter of Oddi dysfunction (SOD) is a syndrome of chronic biliary pain or recurrent pancreatitis due to the functional obstruction of the pancreaticobiliary flow. We report a case of spinal... -
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- Spinal Cord Stimulation for Intractable Visceral Pain due to Chronic Pancreatitis
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Kim JK, Hong SH, Kim MH, Lee JK
- KMID: 2190015
- J Korean Neurosurg Soc.
- 2009 Aug;46(2):165-167.
- doi: 10.3340/jkns.2009.46.2.165
Pain caused by chronic pancreatitis is medically intractable and resistant to conventional interventional or surgical treatment. We report a case of spinal cord stimulation (SCS) for intractable pain due to... -
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- Effects of Non Steroidal Anti-inflammatory Drugs on the Evans Blue Extravasation and Pain Behaviors Evoked by Mustard Oil Induced Visceral Pain in Mice: Comparison with Morphine
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Kim YK, Shin JW, Leem JG, Lee C
- KMID: 2091829
- Korean J Anesthesiol.
- 2004 May;46(5):613-619.
- doi: 10.4097/kjae.2004.46.5.613
BACKGROUND: Visceral pain is characterized by its spontaneous pain and referred hyperalgesia. Our aim was to examine the inhibitory effects of various NSAIDs on the pain behaviors, both spontaneously and... -
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- Experimental Animal Models for the Study of Visceral Pain
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Sohn CI
- KMID: 2084988
- Korean J Gastroenterol.
- 2001 Aug;38(2):77-82.
Functional gastrointestinal disorders are characterized by chronic or recurrent symptoms, which are not explained by structural or biochemical abnormalities. These disorders seem to relate with abnormalities in motility and/or afferent... -
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- Mechanism of transmission and modulation of renal pain in cats; effect of nucleus raphe magnus stimulation on renal pain
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Baik EJ, Jeong Y, Nam TS, Kim WK, Paik KS
- KMID: 1066885
- Yonsei Med J.
- 1995 Aug;36(4):348-360.
- doi: 10.3349/ymj.1995.36.4.348
Initially, when periaqueductal gray (PAG) is electrically stimulated, analgesia is induced, and this phenomenon is called stimulation-produced analgesia. Nucleus raphe magnus (NRM) as well as PAG are known to be... -
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- Introduction of Visceral Pain Model to Test of Visceral Nociception in the Rats
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Lee CW
- KMID: 2104665
- J Korean Pain Soc.
- 1995 Apr;8(1):25-30.
Anlgesic agents against visceral pain typically rely on a noxious chemical irritation of the peritoneum, e. g., acetic acid and phenylquinone writhing test. While useful, this type of assay depends... -
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