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Distribution of Pathogenic Vibrio Species in the Coastal Seawater of South Korea (2017–2018)

Lee SH, Lee HJ, Myung GE, Choi EJ, Kim IA, Jeong YI, Park GJ, Soh SM

OBJECTIVES: Pathogenic Vibrio species are widely distributed in warm estuarine and coastal environments, and can infect humans through the consumption of raw or mishandled contaminated seafood and seawater. For this...
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Cholera Outbreaks in Korea after the Liberation in 1945: Clinical and Epidemiological Characteristics

Kim YS

The characteristics of cholera epidemics that have occurred in Korea since the country's liberation in 1945 are described. The cholera outbreak in 1946 was the last classical one that occurred...
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Immunogenicity of a bivalent killed thimerosal-free oral cholera vaccine, Euvichol, in an animal model

Lee EY, Lee S, Rho S, Kim JO, Choi SK, Lee YJ, Park JY, Song M, Yang JS

PURPOSE: An oral cholera vaccine (OCV), Euvichol, with thimerosal (TM) as preservative, was prequalified by the World Health Organization (WHO) in 2015. In recent years, public health services and regulatory...
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High Frequency of Enteric Protozoan, Viral, and Bacterial Potential Pathogens in Community-Acquired Acute Diarrheal Episodes: Evidence Based on Results of Luminex Gastrointestinal Pathogen Panel Assay

Hawash YA, Ismail KA, Almehmadi

Infectious diarrhea is endemic in most developing countries. We aimed to investigate the protozoan, viral, and bacterial causes of acute diarrhea in Taif, Saudi Arabia. A cross-sectional prospective 1-year study...
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Epidemiology, management, and prevention of cholera

Bae IG

Cholera is an acute secretory form of diarrhea caused by a potent enterotoxin (cholera toxin) after ingestion of toxigenic Vibrio cholerae of the O1 or O139 serogroups. Although cholera is...
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Primary Bacteremia in Diabetes Patient Caused by Non-O1/non-O139 Vibrio cholerae

Noh CI, Lee JY, Kim HA, Ryu SY

Vibrio cholerae (V. cholerae) serotype O1 or O139 is the etiological agents of cholera. These bacteria are responsible for gastrointestinal infections or more rarely bacteremia in patients with an underlying...
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Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway

Park SK, Seong RK, Kim JA, Son SJ, Kim Y, Yokozawa T, Shin OS

BACKGROUND/OBJECTIVES: Oligonol, mainly found in lychee fruit, is an antioxidant polyphenolic compound which has been shown to have anti-inflammatory and anti-cancer properties. The detailed mechanisms by which oligonol may act...
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In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139

Islam MS, Shahik SM, Sohel M, Patwary NI, Hasan MA

In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in...
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Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea

Baik YO, Choi SK, Kim JW, Yang JS, Kim IY, Kim CW, Hong JH

The safety, tolerability and immunogenicity of an oral cholera vaccine (OCV) was assessed in adult Korean male through an open-label, non-comparative clinical study. Two doses of vaccine with an interval...
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Non-O1, Non-O139 Vibrio cholerae Septicemia after Acupuncture

Lim TS, Ji AY, Lee JH, Chang S, Kim IS, Kim YJ, Kim BK, Kim SU, Park JY, Ahn SH, Han KH, Kim DY

Vibrio cholerae is mainly known to cause gastrointestinal infection after seawater exposure or raw seafood intake. It is rarely reported to cause cellulitis or sepsis, but threre has been no...
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Genetic Characteristics and Relatedness of Imported Vibrio cholerae O1 Biotype El Tor in Korea

Kim H, Jeon S, Kim J, Kim S, Lee DY

BACKGROUND: Cholera is a representative water-borne disease that is caused by V. cholera ctx (+). V. cholera El Tor was previously the primary pathogen, but after the seventh pandemic outbreak,...
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A 6-Week Oral Toxicity Study of Oral Cholera Vaccine in Sprague-Dawley Rats

Baek YO, Choi SK, Shin SH, Koo KH, Choi HY, Cha SB, Li YC, Yoo HJ, Lee JY, Kil KH, Kim HS, Kang MS, Kang BH, Kim KH, Bae JS

  • KMID: 1432305
  • Toxicol Res.
  • 2012 Dec;28(4):225-233.
The present study was carried out to examine the toxicity and target organs of oral cholera vaccine (OCV) after repeated oral administration in Sprague-Dawley rats for 6 weeks (3 administrations,...
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Caspase-11, the Main Executioner in Non-canonical Inflammasome

Manzoor Z, Koh YS

Murine caspase-11 is orthologus to human caspase-4 and caspase-5, and is required for the response to cholera toxin B and infection with Escherichia coli, Citrobacter rodentium or Vibrio cholerae. Caspase-11...
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A Case of Liver Abscess and Bacteremia Caused by Vibrio cholerae Non-O1

Lee JW, Kim TS, Jung JW, Park SB, Lee HJ, Lee DG, Lee JN, Lee SH

Vibrio cholerae non-O1 have caused several well-studied food-borne outbreaks of gastroenteritis and also have been responsible for sporadic cases of otitis media, wound infection, and bacteremia. Few cases of liver...
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Pyomyositis Caused by Non-O1 Vibrio Cholerae in a Patient with Liver Cirrhosis

Park SK, Lee JW, Kim JY, Park YS, Seo YH, Cho YK

  • KMID: 2259007
  • Korean J Med.
  • 2011 Mar;80(3):356-359.
A 63-year-old man with underlying liver cirrhosis was admitted with painful swelling of the right thigh. We identified a non-O1 Vibrio cholerae strain in blood cultures and multiple pyomyositis in...
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A case of pyomyositis caused by Vibrio cholerae non-O1 in a patient with liver cirrhosis

Lee KJ, Park KH, Jang HC, Kim SE, Jang MO, Jung SI, Shin JH

  • KMID: 2259170
  • Korean J Med.
  • 2010 Apr;78(4):518-522.
Vibrio cholerae non-O1 mainly causes gastroenteritis and rarely causes extraintestinal infections, such as bacteremia. Skin and soft tissue infections are also possible, but the incidence rate is very low. Although...
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Vaccines for Diarrheal Diseases

Park SE

  • KMID: 2278915
  • Korean J Pediatr Infect Dis.
  • 2009 Dec;16(2):115-122.
Diarrhea is one of the most common causes of morbidity and mortality in children worldwide. Rotavirus is the most common cause of infectious diarrhea both in developed and developing countries....
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Vibrio cholerae non-O1,non-O139 Isolated from Pleural Effusion Following Total Gastrectomy

Suk JH, Lee NY, Lee JH, Oh WS, Peck KR, Song JH

We isolated non-O1, non-O139 Vibrio cholerae from pleural effusion in a patient with recurred advanced gastric caner after total gastrectomy. We also recovered the organism from the patient's stool culture....
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An Epidemiological Survey on the Outbreak of Cholera of Overseas Travelers in Daejeon

Jin SM, Lee TY

  • KMID: 2303889
  • Korean J Epidemiol.
  • 2006 Jun;28(1):119-128.
PURPOSE: This study was coducted to describe the epidemiological, characteristics of the outbreak of cholera of overseas travelers on Aug. 2005 in Daejeon. MATERIALS AND METHODS: Interview using a standard questionnaire...
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Misidentification as Vibrio alginolyticus with Vitek GNI+ Card in Three Cases

Ha GY, Kim MY

  • KMID: 2224700
  • Korean J Clin Microbiol.
  • 2005 Apr;8(1):99-104.
The introduction of a new, fully automated system into the clinical microbiology laboratory contributes to a rapid identification of microorganisms with accurate and reliable results, but such a system requires...
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