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Biotrauma in Ventilator Induced Lung Injury

Kwak SH, Kim SJ

  • KMID: 2301439
  • Korean J Crit Care Med.
  • 2006 Jun;21(1):1-7.
No abstract available.
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Ventilator-Induced Lung Injury

Kim YD

  • KMID: 1472005
  • Korean J Perinatol.
  • 2009 Sep;20(3):201-212.
Positive pressure ventilation (PPV) is one of the most commonly used treatment modalities in the field of neonatology to achieve adequate gas exchange for infants with respiratory difficulties. However, mechanical...
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Ventilator Induced Lung Injury (VILI) and Strategies to Minimize the Injury

Park MS

  • KMID: 2188609
  • J Korean Soc Neonatol.
  • 2004 May;11(1):15-22.
Mechanical ventilation is an indispensable tool for providing gas exchange in many neonatal diseases. Despite the many advances in respiratory technique for neonate during the last several decades, VILI remains...
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Collagen Synthesis in an in Vivo Rat Model of Ventilator-induced Lung Injury

Choi WI

  • KMID: 1513801
  • Korean J Crit Care Med.
  • 2006 Dec;21(2):109-115.
BACKGROUND: Experimentally, maintaining high pressure or high volume ventilation in animal models produces an acute lung injury, however, there was little information on remodeling. We investigated the collagen synthesis in...
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Ventilator-Induced Lung Injury

Kim JH

  • KMID: 2269296
  • Korean J Med.
  • 2014 May;86(5):529-536.
Ventilator-induced lung injury (VILI) is the additional inflammatory damage caused by mechanical ventilation, especially in acute respiratory distress syndrome (ARDS). VILI can induce a systematic inflammatory response, resulting in multiple...
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New Modes of Ventilation for Neonates

Son DW

Many premature infants require mechanical ventilatory support and oxygen supply. Because they have immature lungs, these ventilator supports contribute to the development of ventilator induced lung injury, which causes the...
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Monitoring and Interpretation of Mechanical Ventilator Waveform in the Neuro-Intensive Care Unit

Park J

Management of mechanical ventilation is essential for patients with neuro-critical illnesses who may also have impairment of airways, lungs, respiratory muscles, and respiratory drive. However, balancing the approach to mechanical...
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Lng Injury Induced during Resuscitation of the Preterm Newborns in the Delivery Room

Lee HS

  • KMID: 2072246
  • Korean J Perinatol.
  • 2010 Mar;21(1):1-14.
Neonatologists are deeply concerned with the concept of ventilator-induced lung injury (VILI) and they are greatly careful in the neonatal intensive care unit to apply positive-pressure ventilation (PPV) strategies that...
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Comparison of the Clinical Effects of the Different Ventilatory Care Strategies in the Neonates with Acute Respiratory Failure: High Flow Rate - Constant Flow Rate

Park JD, Kim BI, Choi JH

  • KMID: 2098989
  • J Korean Soc Neonatol.
  • 1999 Nov;6(2):145-153.
PURPOSE: High flow rate (FR) and pressure limit (PL) strategy with time-cycled pressure-limited (TCPL) ventilator is employed routinely in the neonates. Theoretical basis of this strategy is the two-compartment...
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Ventilation accelerates lung injury in septic mice

Jung S, Kim S, Cho H, Jeong I, Park J, Jung DI, Yu D

Sepsis is one of the systemic inflammatory responses, and it can cause acute respiratory distress syndrome (ARDS). Mechanical ventilation (MV) is one of the best treatments in patients with sepsis...
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New Modalities and Modes in Neonatal Ventilation Therapy

Kim HS

  • KMID: 2053720
  • Hanyang Med Rev.
  • 2009 Nov;29(4):338-345.
Despite of the development of neonatal medicine, ventilator induced lung injury has remained as one of the unsolved problems in preterm infants. Recently new modalities and modes of ventilation have...
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Effect of Hypothermia on the Prevention of Ventilator-Induced Lung Injury in Rats

Lim CM, Hong SB, Koh Y, Shim TS, Lee SD, Kim WS, Kim DS, Kim WD

BACKGROUND: Because ventilator-induced lung injury is partly dependent on the intensity of vascular flow, we hypothesized that hypothermia may attenuate the degree of such an injury through a reduced cardiac...
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The volatile anesthetic sevoflurane attenuates ventilator-induced lung injury through inhibition of ERK1/2 and Akt signal transduction

Kim SH, Li M, Pyeon TH, So KY, Kwak SH

BACKGROUND: Ventilator-induced lung injury (VILI) sustained during mechanical ventilator support is still a cause of a high rate of morbidity and mortality in intensive care units and in operating rooms....
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Effects of Matrix Metalloproteinase Inhibitor on Ventilator-Induced Lung Injury in Rats

Kim JH, Park SY, Hur GY, Lee SH, Lee SY, Park SM, Suh IB, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

BACKGROUND: Many inflammatory mediators and collagenases are involved in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). The increase of matrix metalloproteinase-9 (MMP-9, gelatinase-B) produced...
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Effect of Steroids on Interleukin-1beta and Tumor Necrosis Factor-alpha Expression due to High Tidal Volume in the Rat Ventilator-induced Lung Injury Model

So BH, Oh DR, Lee MJ, Lee WJ, Kim SK, Wang YP, Rha SJ

  • KMID: 2194084
  • J Korean Soc Emerg Med.
  • 2002 Jun;13(2):141-146.
PURPOSE: Although mechanical ventilation is used to improve oxygenation, this strategy can impose injurious mechanical stress on lung tissue. This is recognized as ventilator-induced lung injury (VILI). Recently, several studies...
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Respiratory support with heated humidified high flow nasal cannula in preterm infants

Jeon GW

The incidence of bronchopulmonary dysplasia (BPD) has not decreased over the last decade. The most important way to decrease BPD is by weaning the patient from the ventilator as soon...
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Evaluation of Respiratory Parameters in Patients with Acute Lung Injury Receiving Adaptive Support Ventilation

Lee KS, Chung WY, Jung YJ, Park JH, Sheen SS, Hwang SC, Park KJ

  • KMID: 2319465
  • Tuberc Respir Dis.
  • 2011 Jan;70(1):36-42.
BACKGROUND: Adaptive support ventilation (ASV), an automated closed-loop ventilation mode, adapts to the mechanical characteristics of the respiratory system by continuous measurement and adjustment of the respiratory parameters. The adequacy...
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Brain Injury and Neurodevelopmental Sequelae Following Mechanical Ventilation in Preterm Infants

Chang YP

  • KMID: 2188607
  • J Korean Soc Neonatol.
  • 2004 May;11(1):6-14.
In the care of neonates, complications from the use of mechanical ventilation and other treatment of respiratory problems have important effects on cardiac output, cerebral blood flow, cerebral oxygenation and...
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Effects of Transglutaminase 2 Inhibition on Ventilator-Induced Lung Injury

Suh IB, Yoon DW, Oh WO, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Lee SY, Shin C, Shim JJ, In KH, Kang KH, Kim JH

This study was performed to examine the role of transglutaminase 2 (TG2) in ventilator-induced lung injury (VILI). C57BL/6 mice were divided into six experimental groups: 1) control group; 2) lipopolysaccharide...
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The Effect of High Frequency Jet Ventilation with Partial Liquid Ventilation in Saline Lavaged Lung Injury in the Rabbit

Huh IY, Jo MS, Choi C

BACKGROUND: Morbidity and mortality rates from acute respiratory failure remain noteworthy despite advances in conventional ventilatory techniques and improvements in supportive care. Repeated, the large tidal volume breaths during positive...
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