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The effect of alpha-lipoic acid on expression of VCAM-1 in type 2 diabetic rat

Ismawati , Mukhyarjon , Asni E, Romus I

Macrovascular diabetes complications are generally caused by a process called atherosclerosis. Evidences suggest that to initiate atherosclerosis, oxidated low-density lipoprotein (oxLDL) has to promote the expression of adhesion molecule. Several...
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Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors

Kim MJ, Kim T, Suh GJ, Kwon WY, Kim KS, Jung YS, Ko JI, Shin SM, Lee AR

OBJECTIVE: This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and...
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Vascular Cell Adhesion Molecule 1, Intercellular Adhesion Molecule 1, and Cluster of Differentiation 146 Levels in Patients with Type 2 Diabetes with Complications

Hocaoglu-Emre FS, Saribal D, Yenmis G, Guvenen G

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a multisystemic, chronic disease accompanied by microvascular complications involving various complicated mechanisms. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1),...
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Ig-like domain 6 of VCAM-1 is a potential therapeutic target in TNFα-induced angiogenesis

Kim TK, Park CS, Na HJ, Lee K, Yoon A, Chung J, Lee S

Tumor necrosis factor alpha (TNFα)-induced angiogenesis plays important roles in the progression of various diseases, including cancer, wet age-related macular degeneration, and rheumatoid arthritis. However, the relevance and role of...
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Lobaric Acid Inhibits VCAM-1 Expression in TNF-alpha-Stimulated Vascular Smooth Muscle Cells via Modulation of NF-kappaB and MAPK Signaling Pathways

Kwon IS, Yim JH, Lee HK, Pyo S

Lichens have been known to possess multiple biological activities, including anti-proliferative and anti-inflammatory activities. Vascular cell adhesion molecule-1 (VCAM-1) may play a role in the development of atherosclerosis. Hence, VCAM-1...
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NADPH Oxidase and Mitochondrial ROS are Involved in the TNF-alpha-induced Vascular Cell Adhesion Molecule-1 and Monocyte Adhesion in Cultured Endothelial Cells

Yu JH, Kim CS, Yoo DG, Song YJ, Joo HK, Kang G, Jo JY, Park JB, Jeon BH

  • KMID: 1587401
  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):217-222.
Atherosclerosis is considered as a chronic inflammatory process. However, the nature of the oxidant signaling that regulates monocyte adhesion and its underlying mechanism is poorly understood. We investigated the role...
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Ascochlorin Derivative, AS-6, Inhibits TNF-alpha-Induced fractalkine, MCP-1 and VCAM-1 Expression in Rat Aortic Smooth Muscle Cells

Jang YY, Kim SY, Kim NK, Kim MK, Kim HK, Kim HS, Nam CW, Ryu SY, Nam SI, Park KG

  • KMID: 2008232
  • J Korean Diabetes Assoc.
  • 2005 Sep;29(5):401-408.
BACKGOUND: Inflammation is one of the key mechanisms in the development and progression of atherosclerosis. Accumulating evidence suggests that peroxisome proliferators- activated receptorgamma(PPARgamma) plays an important role in the prevention...
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Carvedilol Inhibits Expressions of Vascular Cell Adhesion Molecule-1, Intercellular Adhesion Molecule-1, Monocyte Chemoattractant-1, and Interleukin-8 via NF-kappaB Inhibition in Human Endothelial Cells

Kim YS, Ahn Y, Hong MH, Joo SY, Jeong MH, Kim KH, Sohn IS, Park HW, Hong YJ, Kim JH, Kim W, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: Carvedilol is an anti-oxidative, the cardioprotective effects of which are mediated by the inhibition of NF-kappaB activation. The present study was designed to examine the effects of...
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The Clinical Significance of Soluble Intercellular Adhesion Molecule-1 (sICAM-1) and Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) in Kawasaki Disease

Rhee KW, Yun SW, Lee DK, Choi ES, Yoo BH, Lee MK

  • KMID: 1763544
  • Korean J Pediatr.
  • 2005 Jun;48(6):640-648.
PURPOSE: Kawasaki disease (KD) is known as an acute multi-systemic vasculitis with various immunologic abnormalities. Adhesion of leukocyte to endothelial cells is a key event in the sequence of inflammatory...
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The Effects of Intravenous Immunoglobulin(IVIG) and Methylprednisolone on the mRNAs Expressions of VEGF, VCAM-1 and IL-1beta of Human Umbilical Vein Endothelial Cells(HUVEC) Stimulated by IL-1beta

Kim SY, Lim SJ, Han JW, Lee KY, Lee JS

  • KMID: 2279493
  • Korean J Pediatr.
  • 2004 Dec;47(12):1325-1333.
PURPOSE: Kawasaki disease(KD) manifests a systemic vasculitis of unknown etiology in young children. Vascular endothelial growth factor(VEGF), vascular cell adhesion molecule-1(VCAM-1) and interleukin-1 beta(IL-1beta) may play important roles in the...
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Elevated Serum Level of Soluble VCAM-1 in Patients with Type 2 Diabetes Mellitus with Overt Nephropathy

Seo JW, Min WK, Kim YM, Kwon SK, Kim SH, Lee JI, Chang JW, Yang WS, Park SK

  • KMID: 1610149
  • Korean J Nephrol.
  • 2003 May;22(3):294-302.
BACKGROUND: Soluble adhesion molecules including soluble vascular cell adhesion molecule-1 (sVCAM-1) are released during an infalmmatory process such as artherosclerosis. Elevated sVCAM-1 also has been reported in diabetic nephropathy. But,...
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ICAM-1 and VCAM-1 on Human Umbilical Vein Endothelial Cells Infected by Hantaan Virus

Seol MJ, Kang ET, Lee TW, Kim CH, Choi JY, Yoo SJ, Oh DJ, Yu SH

  • KMID: 1889319
  • Korean J Nephrol.
  • 2002 Sep;21(5):706-712.
PURPOSE: Hemorrhagic fever with renal syndrome (HFRS) is an acute febrile disease caused by Hantaan virus. It is believed that various kinds of inflammatory mediators and cytokines might be involved...
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Effect of Transforming Growth Factor-beta1 (TGF-beta1) on the Expression of Vascular cell Adhesion Molecule-1 (VCAM-1) in Cultured Human Peritoneal Mesothelial Cells (HPMCs)

Jung HH, Yang WS, Kim SB, Kim BS, Park SK, Park JS

  • KMID: 1989639
  • Korean J Nephrol.
  • 2002 Nov;21(6):956-965.
BACKGROUND: In early phase of peritonitis, mononuclear cells as well as polymorphonuclear leukocytes migrate rapidly into peritoneal cavity. For the migration of mononuclear cells, the expression of VCAM-1 on peritoneal...
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Effect of High Glucose on the Expression of MCP-1 and VCAM-1 in Cultured Human Peritoneal Mesothelial Cells

Lee JS, Kim SB, Lee SK, Yu SH, Park JS

  • KMID: 1989742
  • Korean J Nephrol.
  • 2001 May;20(3):362-374.
BACKGROUND: High glucose in peritoneal dialysis solution has been implicated in the pathogenesis of peritoneal fibrosis. Macrophages in peritoneal cavity seem to participate in the process of peritoneal fibrosis through...
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Predictive Value of an Immunohistochemical Staining for HLA-DR, ICAM-1 and VCAM-1 in Acute Renal Allograft Rejection

Kim WS, Lee WM, Park CH, Kang CM, Kwak JY, Park MH

  • KMID: 2198972
  • J Korean Soc Transplant.
  • 2001 Dec;15(2):151-157.
PURPOSE: We have evaluated the diagnostic and predictive value of HLA-DR, ICAM-1 and VCAM-1 expression in patients clinically suspected with acute rejection. METHODS: Immunohistochemical staining for HLA-DR, ICAM-1 and VCAM-1 was...
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Expression of Vascular Cell Adhesion Molecule-1 on Vascular Endothelium in Nasal Polyps with Topical Steroid Treatment

Min YG, Jung YH, Kim JW, Rhee CS, Lee SS, Won TB, Oh SJ

  • KMID: 2275824
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Nov;44(11):1164-1167.
BACKGROUND AND OBJECTIVES: Topical steroid therapy may play an important role in reducing the vascular cell adhesion molecule-1(VCAM-1) expression in the nasal polyp. Various adhesion molecules such as VCAM-1 promote...
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Increased Expression of ICAM-1 and VCAM-1 in Human Lupus Nephritis

Park SB, Han SM, Park KK, Kim HC

  • KMID: 2079202
  • Korean J Nephrol.
  • 2001 Nov;20(6):997-1003.
Intercellular adhsion molecule-1(ICAM-1) and vascular cell adhension molecule-1(VCAM-1) are important cell-surface glycoprotein regulating interactions among immune cells, such as accessory and T cells. Recently, the cDNA encoding the ICAM-1 and...
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Tumor necrosis factor - a ( TNF - a ) , Vascular cell adhesion molecule - 1 ( VCAM - 1 ) and Lipid peroxide in Maternal plasma of Uncomplicated Pregnancy

Jin KH, Lee GS, Kim SJ, Kwon I, Lee CH, Jung DY, Yi CS, Shin JC, Kim EJ, Kim SP

  • KMID: 2269968
  • Korean J Obstet Gynecol.
  • 2000 Mar;43(3):375-379.
OBJECTIVE: The purpose of study was to assess in a longitudinal study of maternal plasma concentrations of Tumor necrosis factor-alpha(TNF-alpha), Vascular cell adhesion molecule-1(VCAM-1), Lipid peroxide (malonaldehyde, MDA) in...
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Effect of reperfusion with leukocyte-depleted blood on the expression of myocardial vascular cell adhesion molecule-1 ( VCAM-1 ) and myocardial function in isolated working heart perfusion model

Lee JR, Suk CJ, Suh JW, Han JJ

  • KMID: 1581858
  • Korean J Thorac Cardiovasc Surg.
  • 2000 Mar;33(3):213-220.
BACKGROUND: Adhesion of leukocytes to myocardium or vascular endothelium has been known as an importation initial step in the ischemia-reperfusion injury which may affect the cardiac function. Therefore, leukocyte-depleted reperfusion may inhibit...
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Nitric Oxide Inhibits VCAM-1 Expression in Human Peritoneal Mesothelial Cells: Possible Role of Cyclic GMP and NF-kappa B

Kim JH, Yang WS, Kim SB, Park SK, Lee SK, Park JS

  • KMID: 1989883
  • Korean J Nephrol.
  • 2000 Nov;19(6):999-1011.
Leukocyte adhesion to mesothelium is an important step during peritonitis, which may be mediated by adhesion molecules including vascular cell adhesion molecule-1(VCAM-1). Nitric oxide(NO) is known to be an endogenous...
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