- Novel Associations between Related Proteins and Cellular Effects of High-Density Lipoprotein
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Choi S, Park YE, Cheon EJ, Kim KY, Kim M, Ann SJ, Noh HM, Lee J, Lee CJ, Lee ST, Lee C, Lee JE, Lee SH
- KMID: 2470908
- Korean Circ J.
- 2020 Mar;50(3):236-247.
- doi: 10.4070/kcj.2019.0195
BACKGROUND AND OBJECTIVES: Recent studies have examined the structure-function relationship of high-density lipoprotein (HDL). This study aimed to identify and rank HDL-associated proteins involved in several biological function of HDL. METHODS:... -
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- Adipose-Derived Stem Cell Transplantation Inhibits Vascular Inflammatory Responses and Endothelial Dysfunction in Rats with Atherosclerosis
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Fan M, Bai J, Ding T, Yang X, Si Q, Nie D
- KMID: 2460220
- Yonsei Med J.
- 2019 Nov;60(11):1036-1044.
- doi: 10.3349/ymj.2019.60.11.1036
PURPOSE: This study aimed to investigate the effect of adipose-derived stem cell (ADSC) transplantation on atherosclerosis (AS) and its underlying mechanisms. MATERIALS AND METHODS: In our study, rat AS model was... -
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- The effect of alpha-lipoic acid on expression of VCAM-1 in type 2 diabetic rat
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Ismawati , Mukhyarjon , Asni E, Romus I
- KMID: 2451221
- Anat Cell Biol.
- 2019 Jun;52(2):176-182.
- doi: 10.5115/acb.2019.52.2.176
Macrovascular diabetes complications are generally caused by a process called atherosclerosis. Evidences suggest that to initiate atherosclerosis, oxidated low-density lipoprotein (oxLDL) has to promote the expression of adhesion molecule. Several... -
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- Comparison Between Signature Cytokines of Nasal Tissues in Subtypes of Chronic Rhinosinusitis
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Kim DK, Eun KM, Kim MK, Cho D, Han SA, Han SY, Seo Y, Lee DH, Cho SH, Kim DW
- KMID: 2431852
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):201-211.
- doi: 10.4168/aair.2019.11.2.201
PURPOSE: Endotype in chronic rhinosinusitis (CRS) has been established in the last decade. However, the exact immunologic profile of CRS still has controversy because it has a considerable immunologic heterogeneity.... -
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- Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice
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Kee HJ, Ryu Y, Seok YM, Choi SY, Sun S, Kim GR, Jeong MH
- KMID: 2468620
- Clin Hypertens.
- 2019 ;25(1):13.
- doi: 10.1186/s40885-019-0118-8
BACKGROUND: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate... -
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- Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors
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Kim MJ, Kim T, Suh GJ, Kwon WY, Kim KS, Jung YS, Ko JI, Shin SM, Lee AR
- KMID: 2433157
- Clin Exp Emerg Med.
- 2018 Dec;5(4):211-218.
- doi: 10.15441/ceem.17.267
OBJECTIVE: This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and... -
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- Expression of adhesion molecules on CD34+ cells from steady-state bone marrow before and after mobilization and their association with the yield of CD34+ cells
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Cecyn KZ, Kimura EY, Lima DM, Yamamoto M, Bordin JO, de Oliveira JSR
- KMID: 2414366
- Blood Res.
- 2018 Mar;53(1):61-70.
- doi: 10.5045/br.2018.53.1.61
BACKGROUND: Cell adhesion molecules (CAMs) expressed on hematopoietic progenitor cells (HPCs), endothelial cells, and stromal cells play a pivotal role in the mobilization of CD34+ cells. Herein, we conducted a... -
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- LPS-stimulated Macrophage Activation Affects Endothelial Dysfunction
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Baek N, Sim S, Heo KS
- KMID: 2409051
- J Bacteriol Virol.
- 2018 Mar;48(1):23-30.
- doi: 10.4167/jbv.2018.48.1.23
Intestinal microbiota is involved in the atherosclerotic process by development of an atheromatous core with foam cells in carotid arteries. It has reported that lipopolysaccharide (LPS) from Escherichia coli localizes... -
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- Protective Effect of Allium tuberosum Extract on Vascular Inflammation in Tumor Necrosis Factor-α-induced Human Vascular Endothelial Cells
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Hur HJ, Lee AS
- KMID: 2434284
- J Cancer Prev.
- 2017 Dec;22(4):228-233.
- doi: 10.15430/JCP.2017.22.4.228
BACKGROUND: Endothelial adhesion molecule expression induced by pro-inflammatory cytokine plays an important role in vascular endothelial cell injury, leading to vascular disease. Allium tuberosum (AT), which is used as a... -
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- Impact of high serum Immunoglobulin E levels on the risk of atherosclerosis in humans
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Unal D, Gelincik A, Elitok A, Demir S, Olgac M, Coskun R, Kocaaga M, Colakoglu , Buyukozturk S
- KMID: 2396928
- Asia Pac Allergy.
- 2017 Apr;7(2):74-81.
- doi: 10.5415/apallergy.2017.7.2.74
BACKGROUND: Epidemiological studies show that immunoglobulin E (IgE) levels were higher in subjects with acute coronary events. However, it is unknown if the increased IgE level is a marker of... -
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- Vascular Cell Adhesion Molecule 1, Intercellular Adhesion Molecule 1, and Cluster of Differentiation 146 Levels in Patients with Type 2 Diabetes with Complications
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Hocaoglu-Emre FS, Saribal D, Yenmis G, Guvenen G
- KMID: 2413293
- Endocrinol Metab.
- 2017 Mar;32(1):99-105.
- doi: 10.3803/EnM.2017.32.1.99
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a multisystemic, chronic disease accompanied by microvascular complications involving various complicated mechanisms. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1),... -
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- Potential involvement of glycogen synthase kinase (GSK)-3β in a rat model of multiple sclerosis: evidenced by lithium treatment
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Ahn M, Kim J, Park C, Cho J, Jee Y, Jung K, Moon C, Shin T
- KMID: 2390426
- Anat Cell Biol.
- 2017 Mar;50(1):48-59.
- doi: 10.5115/acb.2017.50.1.48
Glycogen synthase kinase (GSK)-3β has been known as a pro-inflammatory molecule in neuroinflammation. The involvement of GSK-3β remains unsolved in acute monophasic rat experimental autoimmune encephalomyelitis (EAE). The aim of... -
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- Ig-like domain 6 of VCAM-1 is a potential therapeutic target in TNFα-induced angiogenesis
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Kim TK, Park CS, Na HJ, Lee K, Yoon A, Chung J, Lee S
- KMID: 2375024
- Exp Mol Med.
- 2017 Feb;49(2):e294.
- doi: 10.1038/emm.2016.147
Tumor necrosis factor alpha (TNFα)-induced angiogenesis plays important roles in the progression of various diseases, including cancer, wet age-related macular degeneration, and rheumatoid arthritis. However, the relevance and role of... -
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- Beneficial effects of tonsillectomy plus steroid pulse therapy on inflammatory and tubular markers in patients with IgA nephropathy
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Maruyama S, Gohda T, Suzuki Y, Suzuki H, Sonoda Y, Ichikawa S, Li Z, Murakoshi , Horikoshi , Tomino Y
- KMID: 2364288
- Kidney Res Clin Pract.
- 2016 Dec;35(4):233-236.
- doi: 10.1016/j.krcp.2016.09.002
BACKGROUND: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide. Tonsillectomy plus steroid pulse therapy has been able to induce clinical remission in early-stage IgAN. However, its... -
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- Diagnostic Value of Combining Tumor and Inflammatory Markers in Lung Cancer
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Yoon HI, Kwon OR, Kang KN, Shin YS, Shin HS, Yeon EH, Kwon KY, Hwang I, Jeon YK, Kim Y, Kim CW
- KMID: 2367577
- J Cancer Prev.
- 2016 Sep;21(3):187-193.
- doi: 10.15430/JCP.2016.21.3.187
BACKGROUND: Despite major advances in lung cancer treatment, early detection remains the most promising way of improving outcomes. To detect lung cancer in earlier stages, many serum biomarkers have been... -
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- Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis
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Kang Y
- KMID: 2308849
- Endocrinol Metab.
- 2016 Jun;31(2):206-212.
- doi: 10.3803/EnM.2016.31.2.206
Bone metastasis is a frequent occurrence in breast cancer, affecting more than 70% of late stage cancer patients with severe complications such as fracture, bone pain, and hypercalcemia. The pathogenesis... -
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- Effects of Angiotensin-II Receptor Blocker on Inhibition of Thrombogenicity in a Canine Atrial Fibrillation Model
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Choi JI, Jung JS, Kim MK, Sim J, Kim JS, Lim HE, Park SW, Kim YH
- KMID: 2344446
- Korean Circ J.
- 2016 May;46(3):335-342.
- doi: 10.4070/kcj.2016.46.3.335
BACKGROUND AND OBJECTIVES: Angiotensin-II receptor blockers (ARBs) are known to reduce the development of atrial fibrillation (AF) through reverse-remodeling. However, the effect of ARBs on thrombogenicity in AF remains unknown. MATERIALS... -
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- Lobaric Acid Inhibits VCAM-1 Expression in TNF-alpha-Stimulated Vascular Smooth Muscle Cells via Modulation of NF-kappaB and MAPK Signaling Pathways
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Kwon IS, Yim JH, Lee HK, Pyo S
- KMID: 2170537
- Biomol Ther.
- 2016 Jan;24(1):25-32.
- doi: 10.4062/biomolther.2015.084
Lichens have been known to possess multiple biological activities, including anti-proliferative and anti-inflammatory activities. Vascular cell adhesion molecule-1 (VCAM-1) may play a role in the development of atherosclerosis. Hence, VCAM-1... -
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- Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist's Perspective
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Jang TY, Kim YH
- KMID: 2380842
- Int Neurourol J.
- 2015 Sep;19(3):142-150.
- doi: 10.5213/inj.2015.19.3.142
Interleukin (IL) 33, a member of the IL-1 superfamily, is an "alarmin" protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are... -
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- Nafamostat Mesilate Inhibits TNF-alpha-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production
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Kang MW, Song HJ, Kang SK, Kim Y, Jung SB, Jee S, Moon JY, Suh KS, Lee SD, Jeon BH, Kim CS
- KMID: 1791423
- Korean J Physiol Pharmacol.
- 2015 May;19(3):229-234.
- doi: 10.4196/kjpp.2015.19.3.229
Nafamostat mesilate (NM) is a serine protease inhibitor with anticoagulant and anti-inflammatory effects. NM has been used in Asia for anticoagulation during extracorporeal circulation in patients undergoing continuous renal replacement... -
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