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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Neuroimmune interactions and kidney disease

Hasegawa S, Inoue T, Inagi R

The autonomic nervous system plays critical roles in maintaining homeostasis in humans, directly regulating inflammation by altering the activity of the immune system. The cholinergic anti-inflammatory pathway is a well-studied...
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Intraoperative Vagal Nerve Stimulation in a Patient with Long QT Syndrome during Thyroidectomy

Kritikos G, Christoforides C, Moutafis D, Papandrikos I, Arambatzi , Misichronis G, Koureas A, Dionigi G, Vamvakidis K

Intraoperative neural monitoring (IONM) of the recurrent laryngeal nerve is a useful tool during thyroidectomies for the safe accomplishment of the operation. The latest guidelines suggest that stimulation of vagus...
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Epilepsy Surgery in 2019: A Time to Change

Phi JH, Cho BK

Epilepsy has been known to humankind since antiquity. The surgical treatment of epilepsy began in the early days of neurosurgery and has developed greatly. Many surgical procedures have stood the...
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The Present and Future of Vagus Nerve Stimulation

Yang J, Phi JH

Epilepsy is one of the major chronic neurological diseases affecting many patients. Resection surgery is the most effective therapy for medically intractable epilepsy, but it is not feasible in all...
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Standards for Intraoperative Neuromonitoring in Thyroid Operations

Kim HY, Liu X, Chai YJ, Tufano R, Dralle H, Dionigi G, the Korean Intraoperative Neural Monitoring Society (KINMoS)

After the introduction of intraoperative neural monitoring (IONM) of the recurrent laryngeal nerve (RLN) in clinical thyroid practice almost 16 years ago, the procedure has expanded rapidly with an area-wide...
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The Application of Brain Stimulation in Psychiatric Disorders: An Overview

Roh D, Kang LY, Kim DH

Based on advances in biotechnology and neuroscience, neuromodulation is poised to gain clinical importance as a treatment modality for psychiatric disorders. In addition to old-established electroconvulsive therapy (ECT), clinicians are...
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Neuro-stimulation Techniques for the Management of Anxiety Disorders: An Update

Kar SK, Sarkar S

Neuro-stimulation techniques have gradually evolved over the decades and have emerged potential therapeutic modalities for the treatment of psychiatric disorders, especially treatment refractory cases. The neuro-stimulation techniques involves modalities like...
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Brain Stimulation and Modulation for Autism Spectrum Disorder

Kim T, Ryu JE, Bahn GH

Autism spectrum disorder (ASD) is characterized by a range of conditions including impairments in social interaction, communication, and restricted and repetitive behaviors. Pharmacological treatments can improve some symptoms of ASD,...
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Feasibility and Safety of Transcutaneous Vagus Nerve Stimulation Paired with Notched Music Therapy for the Treatment of Chronic Tinnitus

Shim HJ, Kwak MY, An YH, Kim DH, Kim YJ, Kim HJ

BACKGROUND AND OBJECTIVES: A recent study demonstrated that tinnitus could be eliminated by vagus nerve stimulation (VNS) paired with notched sounds in a rat tinnitus model. The aims of this...
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Radiofrequency Catheter Ablation for Atrial Fibrillation Elicited "Jackhammer Esophagus": A New Complication Due to Vagal Nerve Stimulation?

Tolone S, Savarino E, Docimo L

  • KMID: 2381310
  • J Neurogastroenterol Motil.
  • 2015 Oct;21(4):612-615.
  • doi: 10.5056/jnm15034
Radiofrequency catheter ablation (RFCA) is a potentially curative method for treatment of highly symptomatic and drug-refractory atrial fibrillation (AF). However, this technique can provoke esophageal and nerve lesion, due to...
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Cervical Vagal Nerve Stimulation Activates the Stellate Ganglion in Ambulatory Dogs

Rhee KS, Hsueh CH, Hellyer JA, Park HW, Lee YS, Garlie J, Onkka P, Doytchinova AT, Garner JB, Patel J, Chen LS, Fishbein M, Everett T, Lin SF, Chen PS

BACKGROUND AND OBJECTIVES: Recent studies showed that, in addition to parasympathetic nerves, cervical vagal nerves contained significant sympathetic nerves. We hypothesized that cervical vagal nerve stimulation (VNS) may capture the...
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Therapeutic Modalities for Treatment Resistant Depression: Focus on Vagal Nerve Stimulation and Ketamine

Shah A, Carreno FR, Frazer A

  • KMID: 2279940
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):83-93.
Treatment resistant depression (TRD) is a global health concern affecting a large proportion of depressed patients who then require novel therapeutic options. One such treatment option that has received some...
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Surgically treatable dementia

Kim SH

Dementia is a clinical syndrome that can be caused by multiple conditions, with variable speed of onset, rate of evolution, and duration. Some of these conditions are relentlessly progressive and...
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Surgical Complications of Epilepsy Surgery Procedures : Experience of 179 Procedures in a Single Institute

Lee JH, Hwang YS, Shin JJ, Kim TH, Shin HS, Park SK

OBJECTIVE: There are a few reports on the complications of surgery for epilepsy. We surveyed our data to present complications of epilepsy surgeries from the neurosurgeon's point of view and...
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Effect of Vagus Nerve Stimulation in Post-Traumatic Epilepsy and Failed Epilepsy Surgery : Preliminary Report

Lee HO, Koh EJ, Oh YM, Park SS, Kwon KH, Choi HY

OBJECTIVE: Vagus nerve stimulation (VNS) has been used in epilepsy patients refractory to standard medical treatments and unsuitable candidates for resective or disconnective surgery. In this study, we investigated the...
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Therapeutic Effects of Vagus Nerve Stimulation in Intractable Childhood Epilepsy: Experience for 12 Months after VNS Implantation

Oh SM, Park EY, Choi IS, Cho YK, Kim YO, Kim CJ, Woo YJ, Kim JH

Vagus nerve stimulation (VNS) is presently considered an effective mode of treatment in intractable epilepsy. Its efficacy in children, however, has not been as well studied. This study was performed...
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Surgical Treatment of Epilepsy

Chung CK

  • KMID: 2394803
  • J Korean Med Assoc.
  • 2008 Mar;51(3):262-272.
More than 30% of epilepsy patients are not controlled by anti-epileptic medications. For patients having intractable epilepsy, epilepsy surgery is an effective treatment, which provides not only control of seizures...
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Multimodal Management of Lennox-Gastaut Syndrome

Yum MS, Hong SH, Lee JK, You SJ, Kim DS, Ko TS

  • KMID: 2329514
  • J Korean Child Neurol Soc.
  • 2007 Nov;15(2):154-161.
PURPOSE: Lennox-Gastaut syndrome(LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike and wave activities in the EEG, multiple types of epileptic seizures, and slow...
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