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Spectrum of Pulmonary Fibrosis from Interstitial Lung Abnormality to Usual Interstitial Pneumonia: Importance of Identification and Quantification of Traction Bronchiectasis in Patient Management

Hino T, Lee KS, Han J, Hata A, Ishigami K, Hatabu H

Following the introduction of a novel pathological concept of usual interstitial pneumonia (UIP) by Liebow and Carrington in 1969, diffuse interstitial pneumonia has evolved into UIP, nonspecific interstitial pneumonia (NSIP),...
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Acute Exacerbation of Idiopathic Pulmonary Fibrosis with Lung Cancer: A Comparative Analysis of the Incidence, Survival Rate, and CT Findings with the Patients without Lung Cancer

Cho B, Kang H, Kim JH, Park JG, Park S, Yun JH

Purpose To compare the incidence, survival rate, and CT findings of acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) between patients with and without lung cancer. Materials and Methods From June...
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A Case Report of Usual Interstitial Pneumonia after Treatment of Bronchopneumonia

Lee JU, Shin SR, Kim HJ, Park JH

Usual interstitial pneumonia (UIP) is one type of idiopathic interstitial pneumonia, characterized by its poor prognosis and gradual deterioration of clinical course. So it is important to distinguish UIP from...
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Clinical Year in Review of Interstitial Lung Diseases: Focused on Idiopathic Interstitial Pneumonia

Lee WY

  • KMID: 2319248
  • Tuberc Respir Dis.
  • 2009 Oct;67(4):275-280.
Interstitial lung disease (ILD) is a group of diseases characterized by pulmonary interstitial inflammation. Finally the inflammation results in pulmonary fibrosis and impairment of oxygen transportation. The causes of idiopathic...
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HRCT Findings and Clinical Features in Non-specific and Usual Interstitial Pneumonia with Connective Tissue Diseases

Ahn JK, Koh EM, Lee YS, Cha HS, Chung MP, Han J, Oh DK, Lee KS

OBJECTIVE: The purpose of this study is to assess the clinical characteristics and the serial changes of high resolution CT (HRCT) findings and to correlate those with the results of...
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Short-term Clinical Experience on Interferon gamma-1b Therapy for Idiopathic Pulmonary Fibrosis

Hwang JH, Chung MP, Kang EH, Kim KC, Lee BH, Koh WJ, Suh GY, Kim H, Lee KS, Han J, Kwon OJ

BACKGROUND: Corticosteroids in combination with cytotoxic drugs are the mainstays of therapy for idiopathic pulmonary fibrosis (IPF). However, there has been no regimen showing any survival benefit. The aim of...
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Cyclophosphamide in the Treatment of Idiopathic UIP and NSIP

Jeon K, Chung MP, Shin SC, Yu CM, Koh WJ, Suh GY, Kim H, Kwon OJ, Kim TS, Lee KS, Han J

BACKGROUND: Although corticosteroid and cytotoxic agent such as cyclophosphamide have been used for the treatment of idiopathic interstitial pneumonia (IIP), efficacy of these toxic drugs are unclear because previous reports...
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Prognostic Value of Fibroblastic Foci in Patients with Usual Interstitial Pneumonia

Park YB, Kang GH, Kitaichi M, Shim MS, Lim CM, Lee SD, Koh YS, Kim WS, Kim WD, Kim DS

BACKGROUND: Usual interstitial pneumonia (UIP) is a progressive disorder characterized by a poor response to conventional immunosuppressive agents and significant mortality. The histologic hallmark of UIP is patchy subpleural...
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The Expression of Clara Cell Secretory Protein in BAL Fluid of Patients with Idiopathic Interstitial Pneumonia

Um SW, Han SJ, Choi CM, Lee CH, Yoo CG, Lee CT, Han SK, Shim YS, Kim YW

BACKGROUND: Idiopathic interstitial pneumonia is characterized by chronic inflammation and pulmonary fibrosis. The clara cell 10 kD protein (CC10, also designated CC16) is synthesized by the bronchial epithelium and...
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Clinical Features and Treatment Response in 18 Cases with Idiopathic Nonspecific Interstitial Pneumonia

Kang EH, Chung MP, Kang SJ, An CH, Ahn JW, Han JH, Lee KS, Lim SY, Suh GY, Kim HJ, Kwon OJ, Rhee CH

BACKGROUND: Nonspecific interstitial pneumonia (NSIP) has been reported recently to show much better response to medical treatment and better prognosis compared with idiopathic UIP. However, clinical characteristics of idiopathic NSIP discriminating from...
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Short-Term Efficacy of Steroid and Immunosuppressive Drugs in Patients with Idiopathic Pulmonary Fibrosis and Pre-treatment Factors Associated with Favorable Response

Kang KW, Park SJ, Koh YM, Lee SP, Suh GY, Chung MP, Han J, Kim H, Kwon OJ, Lee KS, Rhee CH

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a diffuse inflammatory and fibrosing process that occurs within the interstitium and alveolus of the lung with invariably poor prognosis. The major problem in...
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