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Clinically undetected plasmacytoid urothelial carcinoma of the urinary bladder with non-mass-forming metastases in multiple organs: an autopsy case

Asano Y, Miyai K, Yoshimatsu S, Sasaki M, Ikewaki K, Matsukuma S

This case report outlines a clinically undetected urinary bladder plasmacytoid urothelial carcinoma (PUC) with multiple metastases detected at autopsy. An 89-year-old man presented with edema in the lower limbs. Pleural...
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Cancer of Unknown Primary: Diagnosis and Treatment

Kim YS, Lee SI

Cancer of unknown primary (CUP) is a heterogenous group of cancers for which the anatomical site of origin is unidentifiable on the basis of standard evaluation and imaging. CUPs account...
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Anaplastic Lymphoma Kinase Positive Large B-cell Lymphoma Mimicking Metastatic Carcinoma of the Cervical Lymph Node from an Unknown Primary Lesion

Kim SW, Lee K, Kim BH, Kim EJ

Anaplastic lymphoma kinase positive large B-cell lymphoma (ALK+LBCL) is a rare subtype of B-cell lymphoma with aggressive features and a poor prognosis. The rarity of this disease and similarity of...
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Prognosis of patients with axillary lymph node metastases from occult breast cancer: analysis of multicenter data

Kim H, Park W, Kim SS, Ahn SJ, Kim YB, Kim TH, Kim JH, Choi JH, Park HJ, Chang JS, Choi DH

Purpose: This study was conducted to evaluate prognosis of patients with level I/II axillary lymph node metastases from occult breast cancer (OBC). Materials and Methods: Data of 53 patients with...
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Treatment Outcomes of Patients with Head and Neck Squamous Cell Carcinoma of Unknown Primary

Park KS, Lim HR, Jeong SH, Lee DH, Lim SC

The purpose of this study was to evaluate clinical characteristics and treatment outcome of patients with head and neck squamous cell carcinoma of unknown primary (HNSCCUP), treated according to the...
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The Role of 18F-FDG PET/CT for Evaluation of Cervical Metastatic Lymph Nodes in a Patient with Metallic Artifacts from Dental Prosthesis: a Case Report

Park JY, Lee YH

Cervical metastasis of squamous cell carcinoma from an unknown primary site occurs in approximately 2–4% of head and neck tumor cases. Without identification of the primary site, proper management cannot...
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Clinical Impact of F-18 FDG PET-CT on Biopsy Site Selection in Patients with Suspected Bone Metastasis of Unknown Primary Site

Yoo SW, Chowdhury MSA, Jeon S, Kang SR, Lee C, Jabin Z, Kim J, Cho SG, Song HC, Bom HS, Min JJ, Kwon SY

Purpose We investigated the clinical role of F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography(PET-CT) in the identification of the primary site and the selection of the optimal biopsy site in...
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Cancer of Unknown Primary Site Mimicking Retroperitoneal Fibrosis

Park CK, Yoo SJ, Yoo IS, Kim J, Shim SC, Yeo MK, Kang SW

Retroperitoneal fibrosis (RPF) is a rare disease characterized by marked fibro-inflammatory tissue in the retroperitoneum. Approximately 70% of cases of RPF are idiopathic, while the rest can be secondary to...
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FDG PET/CT and Conventional Imaging Methods in Cancer of Unknown Primary: an Approach to Overscanning

Cetin Avci N, Hatipoglu , Alacacıoglu A, Bayar EE, Bural GG

PURPOSE: To compare the performance of fluorine-18 fluorodeoxyglucose positron emission tomography and computed tomography (FDG PET/CT) with conventional imaging methods (CIM), including computed tomography (CT), magnetic resonance imaging (MRI), and...
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The Clinical Significance of Occult Gastrointestinal Primary Tumours in Metastatic Cancer: A Population Retrospective Cohort Study

Hannouf MB, Winquist E, Mahmud SM, Brackstone M, Sarma S, Rodrigues , Rogan PK, Hoch JS, Zaric GS

PURPOSE: The purpose of this study was to estimate the incidence of occult gastrointestinal (GI) primary tumours in patients with metastatic cancer of uncertain primary origin and evaluate their influence...
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Accuracy of Diagnostic Methods for Detection of Head and Neck Primary Origin in Metastatic Neck Mass

Kim HD, Yoon HJ, Kim KH, Song CM, Ji YB, Tae K

BACKGROUND AND OBJECTIVES: It is important to localize the primary site when cervical lymph node metastasis is detected. The purpose of this study was to evaluate the accuracy of diagnostic...
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Optimal Treatment Decision for Brain Metastases of Unknown Primary Origin: The Role and Timing of Radiosurgery

Han HJ, Chang WS, Jung HH, Park YG, Kim HY, Chang JH

BACKGROUND: Up to 15% of all patients with brain metastases have no clearly detected primary site despite intensive evaluation, and this incidence has decreased with the use of improved imaging...
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The Results of Occult Breast Carcinoma Treated with Axillary Node Dissection Only: Five Cases Reports

Kim Y, Kim H, Cho J, Kwon S, Yeo S, Kang SH

Herein, we report five cases of occult breast cancer treated with axillary node dissection only, without breast surgery or whole breast radio-therapy. The patients complained of a large, hard mass...
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A Case of Metachronous Human Papilloma Virus-Associated Squamous Cell Carcinomas in Head and Neck

Kim BK, Lee GJ, Kim BY, Chung MK

Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck...
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Undiagnosed Anaplastic Ganglioglioma Resulting in the Sudden Unexpected Death of a Young Woman

Kim MY, Kim H, Park SH, Lee SD

Intracranial neoplasms usually have definitive symptoms, causing a need for medical intervention, but a few cases result in sudden unexpected death even before diagnosis. In these cases, autopsy or post-mortem...
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Hepatocellular Carcinoma with Cervical Spine and Pelvic Bone Metastases Presenting as Unknown Primary Neoplasm

Hwang S, Lee J, Lee JM, Hong SH, Lee MA, Chun HG, Chun HJ, Lee SH, Jung ES

The occurrence of hepatocellular carcinoma (HCC) is closely associated with viral hepatitis or alcoholic hepatitis. Although active surveillance is ongoing in Korea, advanced or metastatic HCC is found at initial...
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Dual Time Point 18F-FDG PET/CT Imaging Identifies Bilateral Renal Tuberculosis in an Immunocompromised Patient with an Unknown Primary Malignancy

Subramanyam P, Palaniswamy SS

18F-FDG PET/CT imaging is an established imaging modality for cancer staging and response assessment. Its role in identifying infective and inflammatory pathologies from malignancy is debated. Dual time - point...
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Indolent Metastatic Squamous Cell Carcinoma of Unknown Primary in the Intrathoracic Lymph Node: A Case Report and Review of the Literatures

Kim MJ, Lim SH, Han SJ, Choi KH, Lee SH, Park MW, Kang H, Na JO

Metastatic squamous cell carcinoma from a cancer of unknown primary (CUP) affecting the intrathoracic lymph node is very rare. We reported a case of metastatic squamous cell carcinoma in the...
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Diagnostic Value of 68Ga-DOTATATE PET/CT in Liver Metastases of Neuroendocrine Tumours of Unknown Origin

Tan TH, Lee BN, Hassan SZ

PURPOSE: In neuroendocrine liver metastases of unknown primary, a multimodality approach is usually adopted and consists of transabdominal ultrasound, endoscopic ultrasound (EUS), computed tomography (CT), magnetic resonance imaging (MRI), nuclear...
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Poorly Differentiated Neuroendocrine Carcinoma in a Perigastric Lymph Node from an Unknown Primary Site

Lee HS, Han HS, Lim SN, Jeon HJ, Lee HC, Lee OJ, Yun HY, Lee KH, Kim ST

  • KMID: 1804888
  • Cancer Res Treat.
  • 2012 Dec;44(4):271-274.
Neuroendocrine carcinomas from an unknown primary site are uncommon. The authors report on a case of neuroendocrine carcinoma in a perigastric lymph node (LN) with no primary site. A 52-year-old...
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