Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

51 results
Display

The Roles of miRNAs in Medulloblastoma: A Systematic Review

Mollashahi B, Aghamaleki FS, Movafagh A

Medulloblastoma is considered one of the most threatening malignant brain tumors with an extremely high mortality rate in children. In the medulloblastoma, there are several genes and mutations found to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Deficiency of Follistatin-Like Protein 1 Accelerates the Growth of Breast Cancer Cells at Lung Metastatic Sites

Zhang Y, Xu X, Yang Y, Ma J, Wang L, Meng X, Chen B, Qin L, Lu T, Gao Y

PURPOSE: Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein that has been shown to play a role in various types of cancer. However, the clinical significance and function of FSTL1...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of ionizing radiation at low dose on transgenerational carcinogenesis by epigenetic regulation

Li L, Kim JH, Park HT, Lee JH, Park MK, Lee JW, Lee JC, Lee MJ

The objective of this study was to determine the effect of ionizing radiation (IR) exposure of parents on carcinogenesis of the next generation focusing on the epigenetic perspective to clarify...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
BRIP1/FANCJ Mutation Analysis in a Family with History of Male and Female Breast Cancer in India

Venkateshwari A, Clark DW, Nallari P, Vinod C, Kumarasamy T, Reddy G, Jyothy A, Kumar MV, Ramaiyer R, Palle K

Male breast cancer (MBC) is a rare and poorly studied disease that is a growing global health problem. Interestingly, both the molecular basis of MBC and its histological profile are...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinicopathological Significance of Large Tumor Suppressor (LATS) Expression in Gastric Cancer

Son MW, Song GJ, Jang SH, Hong SA, Oh MH, Lee JH, Baek MJ, Lee MS

PURPOSE: The aims of this study were to evaluate the expression of the large tumor suppressor (LATS) genes LATS1 and LATS2 by immunohistochemical staining of gastric cancer, and to evaluate...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Role of Gastrokine 1 in Gastric Cancer

Yoon JH, Choi WS, Kim O, Park WS

Homeostatic imbalance between cell proliferation and death in gastric mucosal epithelia may lead to gastritis and gastric cancer. Despite abundant gastrokine 1 (GKN1) expression in the normal stomach, the loss...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Regulation and Function of the Peg3 Imprinted Domain

He H, Kim J

A subset of mammalian genes differ functionally between two alleles due to genomic imprinting, and seven such genes (Peg3, Usp29, APeg3, Zfp264, Zim1, Zim2, Zim3) are localized within the 500-kb...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Loss of Heterozygosities in Five Tumor Suppressor Genes (FHIT Gene, p16, pRb, E-Cadherin and p53) in Thyroid Tumors

Kim JH, Choi KY, Lee DJ, Rho YS, Jo SJ

  • KMID: 2278408
  • Clin Exp Otorhinolaryngol.
  • 2014 Mar;7(1):53-58.
OBJECTIVES: To evaluate the loss of heterozygosities (LOH) of chromosomes 3p14 (FHIT gene), 9p21 (p16), 13q21 (pRb), 6q22 (E-cadherin) and 17p13 (p53) in various thyroid tumors. METHODS: Eighty thyroid tumor cases...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
RASSF1A Suppresses Cell Migration through Inactivation of HDAC6 and Increase of Acetylated alpha-Tubulin

Jung HY, Jung JS, Whang YM, Kim YH

  • KMID: 2167619
  • Cancer Res Treat.
  • 2013 Jun;45(2):134-144.
PURPOSE: The RAS association domain family protein 1 (RASSF1) has been implicated in a tumor-suppressive function through the induction of acetylated alpha-tubulin and modulation of cell migration. However, the mechanisms...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Role of the CDH1 Promoter Hypermethylation in the Axillary Lymph Node Metastasis and Prognosis

Jung SP, Kim S, Nam SJ, Kim I, Bae JW

  • KMID: 2374540
  • J Breast Cancer.
  • 2013 Mar;16(1):16-22.
PURPOSE: Hypermethylation of the tumor suppressor genes is frequently observed in the tumor development and progression. However, the correlation between the hypermethylation of the tumor suppressor genes, CDH1 and the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Improved Therapeutic Effect against Leukemia by a Combination of the Histone Methyltransferase Inhibitor Chaetocin and the Histone Deacetylase Inhibitor Trichostatin A

Tran HT, Kim HN, Lee IK, Nguyen-Pham TN, Ahn JS, Kim YK, Lee JJ, Park KS, Kook H, Kim HJ

SUV39H1 is a histone 3 lysine 9 (H3K9)-specific methyltransferase that is important for heterochromatin formation and the regulation of gene expression. Chaetocin specifically inhibits SUV39H1, resulted in H3K9 methylation reduction...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Analysis of copy number abnormality (CNA) and loss of heterozygosity (LOH) in the whole genome using single nucleotide polymorphism (SNP) genotyping arrays in tongue squamous cell carcinoma

Tsukasa K, Nobuharu Y, Takeshi O, Hiroki B, Takashi Y, Akira K, Nobuo T, Takahiko S

Chromosomal loss of heterozygosity (LOH) is a common mechanism for the inactivation of tumor suppressor genes in human epithelial cancers. LOH patterns can be generated through allelotyping using polymorphic microsatellite...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Integrative epigenomic and genomic analysis of malignant pheochromocytoma

Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C

Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Molecular Pathogenesis of Gastric Cancer

Park WS

In this article, I will survey the major genetic susceptibility and somatic genetic alterations involved in gastric cancer and adenoma. These include germline and somatic genetic alterations in oncogenes, tumor...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Gene Mutations in Animal Models: Do Tumor Suppressor Genes, brca1 and brca2, Play a Role in Ovarian Carcinogenesis?

Yi BR, Hwang KA, Choi KC

Ovarian cancer is the most lethal cause of death from gynecological malignancies in the Western world. Over 90% of human ovarian cancers arise in the ovarian surface epithelium (OSE). The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: Do they play a role in ovarian carcinogenesis?

Kim KY, Park DW, Jeung EB, Choi KC

Alterations of genes are known to be critical for the induction of tumorigenesis, but the mechanism of ovarian carcinogenesis is little understood and remains to be elucidated. In this study,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of DNA Methylation Markers for NSCLC Using Hpall-Mspl Methylation Microarray

Kwon MH, Lee GE, Kwon SJ, Choi E, Na MJ, Cho HM, Kim YJ, Sul HJ, Cho YJ, Son JW

  • KMID: 2319131
  • Tuberc Respir Dis.
  • 2008 Dec;65(6):495-503.
BACKGROUND: Epigenetic alterations in certain genes are now known as at least important as genetic mutation in pathogenesis of cancer. Especially abnormal hypermethylation in or near promoter region of tumor...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Methylation Profiles of CpG Island Loci in Major Types of Human Cancers

Park SY, Kim BH, Kim JH, Cho NY, Choi M, Yu EJ, Lee S, Kang GH

Several reports have described aberrant methylation in various types of human cancers. However, the interpretation of methylation frequency in various human cancers has some limitations because of the different materials...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Loss of Heterozygosity of Major Tumor Suppressor Genes in Invasive Ductal Carcinomas

Byun WS, Park CH, Cho SJ, Ahn HG, Nam ES, Cha HJ, Kim KS

PURPOSE: Breast cancer is one of the most frequent malignant tumors in Korea. The major tumor suppressor genes (TSGs) such as p16, Rb, E-cadherin and p53 may play important roles...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Methylation Patterns of Cancer-Associated Genes in Breast Cancer

Jee SB, Park WC, Kim KW, Kim JI, Ahn CH, Lim KW, Oh SJ, Song BJ, Jung SS, Kim JS

PURPOSE: To investigate the methylation status of cancerassociated genes in breast cancer to assess its use in the diagnosis of breast cancer and the relationship with distinctive clinical and pathological...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr