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Partial Interferon-gamma Receptor Deficiency in Patients with Disseminated Tuberculosis

Hwang JH, Koh WJ, Lee SH, Kim EJ, Kang EH, Suh GY, Chung MP, Kim H, Kwon OJ

BACKGROUND: Interferon-gamma (IFN-gamma) is essential in the immune response to mycobacterial infections, and a complete or partial deficiency in the IFN-gamma receptor 1 (IFNgammaR1) or the IFN-gamma receptor 2 (IFNgammaR2)...
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The Correlation between Bronchostenosis and Changes in the Levels of Interferon-gamma and Transforming Growth Factor-beta during the Treatment in patients with Endobronchial Tuberculosis

Kim KU, Lee SJ, Lee JH, Cho WH, Jung KS, Joe JH, Kim YS, Lee MK, Kim YD, Choi YM, Park SK

BACKGROUND: Endobronchial tuberculosis often complicates bronchostenosis, which can cause dyspnea due to an airway obstruction, and can be misdiagnosed as bronchial asthma or lung cancer. This study investigated the possible...
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A Case of Rhabdomyolysis with Community Acquired Pneumonia

Kang YA, Yim JJ, Kim YW, Han SK, Shim YS, Yoo CG

A-67-year old man was hospitalized due to fever, cough and dyspnea upon exertion, and was treated with intravenous antibiotics. During the hospital course he presented with weakness in his low...
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A Case of Interstitial Pneumonitis Caused by Leflunomide

Lee JH, Cheon WS, Seo YI, Eom KS, Jang SH, Bahn JW, Kim DG, Jung KS

Leflunomide is a new disease modifying anti rheumatic drug (DMARD) for the treatment of active rheumatoid arthritis. Its mechanism of action differs from other DMARDs in that it inhibits the...
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Clinical Characteristics and Prognosis of Lymphocyte Dominant Exudative Pleural Effusion with Low ADA, Low CEA, Negative Cytology and Negative AFB Smear

Kang YA, Yoon YS, Lee SW, Choi CM, Kim DK, Lee HS, Ko DS, Yoo CG, Kim YW, Han SK, Shim YS, Yim JJ

BACKGROUND: A pleural effusion is a common medical problem. Despite several diagnostic tests, 15-20% of pleural effusions go undiagnosed. The aim of this study was to evaluate the clinical characteristics...
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A Case of Lemierre Syndrome Associated with Septic Pulmonary Emboli

Kim EJ, Park JH, Kim CH, Park JY, Jung TH, Cha SI

Lemierre syndrome is characterized by an acute oropharyngeal infection with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections such as septic pulmonary emboli and suppurative arthritis....
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A Case of Pulmonary Sequestration Treated with Arterial Embolization

Lee GW, Kim DK, Na HS, Bae JY, Choi JH, Kim YK, Kim KU, Uh ST, Kim DH, Hwang JH, Goo DE

Pulmonary sequestration is a very rare congenital malformation in which a mass of pulmonary tissue is detached from the normal lung and receives its blood supply from a systemic...
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Mediastinitis after Central Venous Catheterization

Keum DY, Park NH, Lee KT

We report here on an uncommon case of mediastinitis that occurred after central venous catheterization. A patient with colon and jejunal cancer complained high fever, right shoulder pain, chest pain,...
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Polymorphisms of Angiotensin-converting Enzyme Gene Associated in Patients with COPD with or without Bronchial Hyperresponsiveness

Kim SS, Choi EG, Park SJ, Lee HB, Lee YC, Rhee YK

BACKGROUND: An insertion-deletion polymorphism of angiotensin converting enzyme (ACE) gene has been shown to be associated with enzyme activity levels of ACE. Reported results that have been mutually contradictory about...
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A Case of Propylthiouracil Induced Diffuse Pulmonary Hemorrhage

Lee SY, Jung JY, Lee KJ, Lee SH, Kim SJ, Lee EJ, Hur GY, Jung HC, Lee SY, Kim JH, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

Propylthiouracil(PUT) is a drug which used at Grave's disease. But PTU has recently been observed to associated with antineutrophil cytoplasmic antibody(ANCA)-positive vasculitis resulting in, infrequently, diffuse alveolar he?morrhage. We report...
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Characterization of Cigarette Smoke Extract (CSE)-induced Cell Death in Lung Epithelial Cells

Choi EK, Kim YS, Park JS, Jee YK, Lee KY

Emphysema is characterized by air space enlarge?ment and alveolar destruction. The mechanism responsible for the development of emphysema was thought to be protease/antiprotease imbalance and oxidative stress. A very recent...
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Expression of Estrogen and Progesterone Receptors in Non- small-cell Lung Cancer Tissue Using Tissue Microarray Method

Han HS, Kim MJ, Cho JH, Yoon YH, Kwak SM, Lee HL, Kim KH, Ryu JS

BACKGROUND: To evaluate the role of estrogen and progesterone in the carcinogenesis of NSCLC, IHC studies for the expression of the receptors of estrogen and pro?gesterone have been performed with...
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Oxidative Inactivation of Peroxiredoxin Isoforms by H2O2 in Pulmonary Epithelial, Macrophage, and other Cell Lines with their Subsequent Regeneration

Oh YJ, Kim YS, Choi YI, Shin SS, Park JH, Choi YH, Park KJ, Park RW, Hwang SC

BACKGROUND: Peroxiredoxins (Prxs) are a relatively newly recognized, novel family of peroxidases that reduce H2O2 and alkylhydroperoxide into water and alcohol, respectively. There are 6 known isoforms of Prxs present...
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