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Pharmacokinetics of ofloxacin in Patients with Multidrug-Resistant Tuberculosis

Park SK, Yoon YR, Lee WC, Jun HM, Shon JH, Kim KA, Park JY, Shin JG

BACKGROUND: There are few studies that have reported on the pharmacokinetic(PK) disposition of fluoroquinolones in patients with multi-drug resistant tuberculosis(MDR-Tb), even though fluoroquinolones are frequentl y co-prescribed to those patients....
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A Case of Idiopathic Hypereosinophilic Syndrome Presenting Acute Pulmonary Edema

Yu KS, Kim YJ, Seo HE, Yoon HJ, Do YK, Lee BK, Kim WH

Transient peripheral eosinophilia occurs in several disorders, such as allergic diseases, cancer, and parasitic in fections. However, in most cases, their persence is not accompanied by tissue destruction or organ...
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The Changes of Cuff Pressure from Endotracheal Intubation for Long-term Mechanical Ventilation

Jung BH, Park W, Koh YS

BACKGROUND: A tracheal stenosis is caused by mucosal ischemic injury related to a high cuff pressure (Pcuff) of the endotracheal tube. In contrast, aspiration of the upper airway secretion and...
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The Clinical Significance of Measurement of Serum Vascular Endothelial Growth Factor in Patients with Hemoptysis

Lo DK, Kim SJ, Lee SY, Kim YK, Kim KH, Moon HS, Song JS, Park SH

BACKGROUND: Hemoptysis is an often alarming presenting symptom and VEGF is a major regulator of both normal and abnormal angiogenesis, including many inflammatory diseases. In this report the clinical significance...
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A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma in the Lung of the Patient with Primary Sjogren's Syndrome

Kang MJ, Lee JM, Lee SJ, Son JW, Kim DG, Lee MG, Hyun IG, Jung KS

A bronchus-associated lymphoid tissue(BALT) lymphoma of the lung is a rare disorder of patients with Sjogren's syndrome. A 49-year-old woman was admitted for an evaluation of exertional dyspnea and general...
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A Case of Primary Localized Tracheobronchial Amyloidosis

Kwak YG, Kim HJ, Lee CH, Kim SY, Cho JH, Kwak SM, Lee HL, Kim JM, Han HS, Ryu JS

Primary pulmonary amyloidosis is a rare condition that can be classified into the tracheobronchial, diffuse alveolar septal, and nodular parenchymal type. Tracheobronchial amyloidosis is characterized by deposition of fib rilar...
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A Case of Primary Pulmonary Sarcoma with Morphologic Features of Malignant Fibrous Histiocytoma

Lee YJ, Hur WH, Lo DK, Kim SJ, Lee SY, Kim YK, Moon HS, Song JS, Park SH, Park GS, Lee KY

A malignant fibrous histiocytoma is a malignant soft tissue neoplasm that occurs frequently in the metaphyseal ends of the long bones of adults. The lung is a common site for...
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GRO-alpha, IL-8 and ENA-78: Expressed by Stimulated Endothelial Cells and Increased PMN Adhesion

Ryu KC, Kim YS, Kim YK, Kim IJ, Kim YD, Lee CH, Park DY, Kim JY, Lee MK, Park SK, Ha TJ

BACKGROUND: Inflammation, where vascular endothelial cells are activated by cytokines, recruits circulating leukocytes such as neutrophils into the tissues. Mononuclear phagocytes as well as tissue cells activated by these stimuli...
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The Expression of MUC1 and CD44s in Non-small Cell Lung Cancer

Park HK, Lee JS, Lee JH, Lee JW, Kim YS, Lee MK, Kim YD, Lee HR, Kim KI, Lee CH, Park SK

BACKGROUND: MUC1 mucin is a heavily glycosylated large glycoprotein and is expressed aberrantly in carcinoma. CD44 is polymorphic family of cell surface glycoproteins participating in cell-cell adhesion and modulat ion...
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Expression of Matrix Metalloproteinases-9 and Stromelysin-3 in Peripheral Blood in Patients with Lung Cancer

Lim SY, Koh WJ, Kim CH, Ahn YM, Kwon YM, Kang KW, Kim HC, Suh GY, Chung MP, Lim SY, Kim HJ, Kwon OJ

BACKGROUND: Matrix metalloproteinases(MMP) are essential enzymes for tumor invasion and metastasis. Among the MMP family, elevated MMP-9 and stromelysin-3(STR-3) expression have been reported to be poor prognostic factors in lung...
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