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Sensitivity of Whole-Blood Interferon-Gamma Release Assay According to the Severity and the Location of Disease in Patients with Active Tuberculosis

Kim YY, Lee J, Lee YJ, Lee SY, Lee YH, Choi KJ, Hwangbo Y, Cha SI, Park JY, Jung TH, Park JS, Kim CH

BACKGROUND: The clinical manifestation of M. tuberculosis infection ranges from asymptomatic latent infection, to focal forms with minimal symptoms and low bacterial burdens, and finally to advanced tuberculosis (TB) with...
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Increasing the Treatment Success Rate of Tuberculosis in a Private Hospital through Public-Private Mix (PPM) Project

Park JS

BACKGROUND: Stopping medical treatment by tuberculosis (TB) patients prior to completing treatment period is a major concern in private hospitals. We evaluated the impact of public-private mix (PPM) project on...
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A Case of Novel Influenza A (H1N1) Virus Pneumonia Complicated Pnemomediastinum and Subcutenous Emphysema

Kim YJ, Kyung SY, Park JW, Jeong SH, Seo YH, Lee SP

Recently, a novel influenza A (H1N1) has been recognized as the cause of a worldwide respiratory infection outbreak. Although the symptoms of a novel influenza A (H1N1) are usually mild,...
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Caplan's Syndrome Presenting as Multiple Pulmonary Nodules

Lee SK, Lee SH, Kim SY, Lee WK, Shin DH, Bang WD, Noh SM, Shim HS, Park BH, Lee KJ, Park MS, Kim YS, Chang J, Kim SK, Kang YA

We report a case of Caplan's Syndrome, which presented as multiple pulmonary nodules. A 58-year-old male was admitted to hospital due to multiple pulmonary nodules. In addition, the patient presented...
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Healthcare-Associated Pneumonia

Lee HB, Han HJ

Pneumonia is frequently encountered in the clinical fields, both as a cause for admission and as a complication of the underlying disorder or as the course of treatment. Pneumonia is...
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A Case of Cranial Nerve Palsy as a Paraneoplastic Syndrome in Non-Small Cell Lung Cancer

Lee YM, Sim WH, Yoon SO, Kim SY, Park JS, Kho BG, Byun MK, Choi YC, Kim HJ

Paraneoplastic neurologic syndrome is a group of assorted disorders resulting from damage to the nervous system in cancer, remote from primary site, and not related to metastasis, infection, or metabolic...
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A Case of Middle Mediastinal Malignant Paraganglioma

Park SB, Park S, Bang SH, Kim EK, Jeon K, Koh WJ, Suh GY, Chung MP, Kim H, Kwon OJ, Go YH, Um SW

Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas....
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Cutaneous Metastasis from Lung Cancer: A Single-Institution Retrospective Analysis

Lee JH, Ahn SJ, Kim HJ, Jang SE, Noh GY, Kim HR, Kim CH, Lee JC

BACKGROUND: Lung cancer is responsible for substantial proportions of cutaneous metastasis from internal malignancies. The aim of this study was to evaluate the clinical manifestations and outcomes of cutaneous metastasis...
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The Macrophage-Specific Transcription Factor Can Be Modified Posttranslationally by Ubiquitination in the Lipopolysaccharide-Treated Macrophages

Jung JW, Choi JC, Kim JY, Park IW, Choi BW, Shin JW, Christman

BACKGROUND: Macrophages are one of the most important inflammatory cells in innate immunity. PU.1 is a macrophage-specific transcription factor. Ubiquitins are the ultimate regulator of eukaryotic transcription. The ubiquitination process...
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Maspin Expression and Its Clinical Significance in Non-Small Cell Lung Cancer

Yoon SH, Kim WJ, Shin KH, Kim MH, Cho WH, Kim KU, Park HK, Jeon DS, Kim YS, Lee CH, Lee MK, Park SK

BACKGROUND: Maspin (mammary serine protease inhibitor) is a member of the serpin superfamily. A few studies have examined the role of maspin in tumor suppression of non-small cell lung cancer...
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