- The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway
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Cheng Z, Zhang Q, Yin A, Feng M, Li H, Liu H, Li Y, Qian L
- KMID: 2440029
- Exp Mol Med.
- 2018 Feb;50(2):e447.
- doi: 10.1038/emm.2017.278
In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because... -
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- TGF-beta Suppresses COX-2 Expression by Tristetraprolin-Mediated RNA Destabilization in A549 Human Lung Cancer Cells
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Kang S, Min A, Im SA, Song SH, Kim SG, Kim HA, Kim HJ, Oh DY, Jong HS, Kim TY, Bang YJ
- KMID: 2380395
- Cancer Res Treat.
- 2015 Jan;47(1):101-109.
- doi: 10.4143/crt.2013.192
PURPOSE: Overexpression of cyclooxygenase 2 (COX-2) is thought to promote survival of transformed cells. Transforming growth factor beta (TGF-beta) exerts anti-proliferative effects on a broad range of epithelial cells. In... -
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- Reduced Interleukin-17 and Transforming Growth Factor Beta Levels in Peripheral Blood as Indicators for Following the Course of Bladder Cancer
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Baharlou R, Vasmehjani AA, Dehghani A, Ghobadifar MA, Khoubyari
- KMID: 2168027
- Immune Netw.
- 2014 Jun;14(3):156-163.
- doi: 10.4110/in.2014.14.3.156
Interleukin (IL) 17 is produced by T-helper (Th) 17 with a vigorous effect on cells of the immune system playing important roles in pathogenesis of immune-mediated diseases, including autoimmune disorders... -
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- Co-stimulation of TLR4 and Dectin-1 Induces the Production of Inflammatory Cytokines but not TGF-beta for Th17 Cell Differentiation
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Chang J, Kim BM, Chang CH
- KMID: 1508826
- Immune Netw.
- 2014 Feb;14(1):30-37.
- doi: 10.4110/in.2014.14.1.30
Collaboration of TLR and non-TLR pathways in innate immune cells, which acts in concert for the induction of inflammatory cytokines, can mount a specific adaptive immune response tailored to a... -
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- Decorin and TGF-beta Expression after Partial Myotomy of the Extraocular Muscle in Rat
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Lim YJ, Kim GN, Lee NE, Kim SJ, Yoo JM
- KMID: 2216463
- J Korean Ophthalmol Soc.
- 2013 Jan;54(1):143-148.
- doi: 10.3341/jkos.2013.54.1.143
PURPOSE: To report the expression of decorin and TGF-beta in partial myotomy of the extraocular muscle in rats. METHODS: Partial myotomy of the superior rectus muscle was performed on the right... -
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- Expression of TGF-beta1, TGF-beta Receptor Type II and VEGF in Colorectal Adenomas and Adenocarcinomas
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Kang SB, Lee SW, Kim YS, Nam SW, Lee DS, Kim JM, Han SW, Choi KY
- KMID: 2038379
- Korean J Gastrointest Endosc.
- 2007 Nov;35(5):313-320.
BACKGROUND/AIMS: The aim of study was to investigate the expression of TGF-beta, TGF-RII and VEGF determined by immunohistochemical analysis with a comparison of the clinicopathological parameters such as tumor size,... -
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- The Prognostic Significance of Chromosome 18 Monosomy in the Colon Cancer: Correlations with the Expressions of Smad4 and TGF-beta Receptor II Proteins
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Choi YS, Lim HM, Kim BG, Lee TJ
- KMID: 2211101
- J Korean Surg Soc.
- 2007 Sep;73(3):227-234.
PURPOSE: Chromosomal instability of chromosome 18 and inhibition of the transforming growth factor beta (TGF-beta) signaling pathway, which is mediated through Smad4, play important roles in the tumorigenesis of colon... -
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- Expression of TGF-beta 1, osteonectin and BMP-4 on bone regeneration in mandibular distraction osteogenesis combination with a compression stimulation
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Park SJ, Kim UK, Chung IK, Hwang DS, Kim YD, Shin SH, Kim CH, Byun JH
- KMID: 2043815
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Aug;33(4):288-296.
Distraction osteogenesis(DO) is a technique of lengthning bone including soft tissue by gradual separation of surgically divided bone surfaces. Distraction osteogenesis combination with a compression stimulation(DO-CO) was a new technique... -
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- Effect of Systemic Steroid on the Expression of TGF-beta and IL-10 in Nasal Polyps
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Lee SS, Go YM, Bae JH, Cho KK
- KMID: 2276767
- Korean J Otolaryngol-Head Neck Surg.
- 2007 Jun;50(6):501-507.
BACKGROUND AND OBJECTIVES: Etiology and pathogenesis of nasal polyps are still not fully understood. Transforming growth factor-beta (TGF-beta) and interleukin-10 (IL-10) are important cytokines for nasal polyp formation and immunomodulation.... -
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- The clinical significance of the expression of TGF-beta 1 and MMP-2 related to the regional lymph node metastasis in the oral squamous cell carcinoma
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Kim JY, Rotaru H, Kim SG
- KMID: 2190265
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Jun;33(3):199-203.
Several matrix metalloproteinases (MMPs) have been shown to play an important role in the invasion and metastasis of oral squamous cell carcinoma (OSCC). The members of the TGF-beta signaling pathway... -
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- Effects of Troglitazone on the Expression of VEGF and TGF-beta in Cultured Rat Mesangial Cells
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Kim DL, Kim NH, Choi DS
- KMID: 1523010
- J Korean Diabetes Assoc.
- 2007 May;31(3):220-229.
- doi: 10.4093/jkda.2007.31.3.220
BACKGROUND: Clinical study reported that troglitazone ameliorated microalbuminuria in diabetic nephropathy. However, the mechanism of action is not fully understood. Vascular endothelial growth factor (VEGF) is known as vascular permeability... -
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- The Analysis of the Expression of TGF-beta in Human Hair Follicles in vivo
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Won CH, Joo YH, Lee DH, An JS, Kim BJ, Kwon OS, Cho KH, Kim KH, Eun HC
- KMID: 1931110
- Korean J Dermatol.
- 2007 Apr;45(4):321-326.
BACKGROUND: Although it is well known that transforming growth factor beta (TGF-beta) may induce catagen change of hair follicles and inhibit hair growth, it is still unclear which subtype of... -
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- The Effect of Genotype of NAT2, TNF-alpha and TGF-beta Genes on Allergic Rhinitis in Korea
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Park YK, Kang JW, Kim YD, Lee CH, Eom SY, Kim H
- KMID: 1593093
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Dec;49(12):1165-1171.
BACKGROUND AND OBJECTIVES: The inflammatory reaction is affected by the genotype or phenotype of genes related with inflammation modulating cytokines and allergen metabolizing enzyme. This study was performed to investigate... -
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- The Regulation of MMP-2 and -14 Expressions by TGF-beta in Lens Epithelial Cells
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Son MJ, Kim JT, Joo CK
- KMID: 2208438
- J Korean Ophthalmol Soc.
- 2006 Jul;47(7):1110-1116.
PURPOSE: TGF-beta is a key regulator of epithelial-mesenchymal transition. Among the TGF-beta responses, cell migration is closely associated with the expression of matrix metalloproteinases (MMPs). Therefore, we determined which MMPs... -
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- The Effect of High Glucose and TGF-beta on the Cellular Injury in Cultured Glomerular Epithelial Cells
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Jeong GH, Chung SC, Jung ED, Doh YJ, Kim HK, Park SH, Park IH, Kim JG, Ha SW, Kim BW, Lee IK, Ko CW
- KMID: 2177595
- J Korean Diabetes Assoc.
- 2006 Jul;30(4):254-263.
- doi: 10.4093/jkda.2006.30.4.254
BACKGROUND: The glomerulus is a complex physiological structure, as well as selective filtration barrier in the control of renal blood flow and blood pressure. Glomerular epithelial cells may play an... -
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- The Effect of Heparin on Gene Expression of Collagen, MMP, TGF-beta Isoforms Using Cultured Fibroblast from Transverse Carpal Ligament of Carpal Tunnel Syndrome
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Jeong SH, Na MH, Lee JS, Song SH, Yoon ES, Dhong ES, Kim HJ
- KMID: 2098427
- J Korean Soc Plast Reconstr Surg.
- 2006 Jul;33(4):427-432.
PURPOSE: Noninflammatory synovial fibrosis has been noted for main causal factor of carpal tunnel syndrome (CTS). Recently, there are some reports that heparin have not only anti-coagulative effect but also... -
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- Ahmed Valve Implantation Result and TGF-beta and VEGF in the Aqueous Humor of Neovascular Glaucoma Patients
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Song WK, Lee JH, Hong YJ, Kim CY
- KMID: 2337323
- J Korean Ophthalmol Soc.
- 2006 Apr;47(4):571-576.
PURPOSE: To assess the relationship of transforming growth factor-beta (TGF-beta) and vascular endothelial growth factor (VEGF) levels in the aqueous humor of neovascular glaucoma (NVG) patients and the results of... -
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- Expression of angiogenin, TGF-beta, VEGF, APEX and TNF-alpha in oral squamous cell carcinoma
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Lee HS, Kim KW, Kim WJ
- KMID: 2190350
- J Korean Assoc Oral Maxillofac Surg.
- 2006 Feb;32(1):8-18.
PURPOSE: The purpose of this study was to verify that the expressions of angiogenin, transforming growth factor-beta(TGF-beta), vascular endothelial growth factor(VEGF), human apurinic/apyrimidinic endonuclease(APEX) and tumor necrosis factoralpha(TNF-alpha) were associated... -
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- Changes of Interleukin-12 and Transforming Growth Factor Beta 1 before and after Antipsychotic Treatments in Schizophrenic Patients
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Kim SJ, Lee BH, Kim YK
- KMID: 2299956
- Korean J Biol Psychiatry.
- 2005 Nov;12(2):143-150.
BACKGROUND: Several reports have suggested that cytokine alterations could be related to the pathophysiology of schizophrenia. In this study, we measured plasma level of interleukin-12(IL-12), a pro-inflammatory T helper 1(Th1)... -
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- The Expression of TGF-beta Isoform mRNA in the Cataract Lens Epithelial Cell
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Kim DH, Yang JW, Park SK, Kim SD, Hur J, Yoon IH, Choi IH
- KMID: 2207856
- J Korean Ophthalmol Soc.
- 2005 Aug;46(8):1393-1400.
PURPOSE: Transforming growth factor (TGF)-beta is recognized as being associated with cataractogenesis. We quantitated the mRNA expression of TGF-beta isoforms in cataractous crystalline lens to determine the effect of the... -
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