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Role of Transforming Growth Factor Alpha in Hepatocarcinogenesis

Lee DH

  • KMID: 2241295
  • Korean J Hepatol.
  • 2000 Mar;6(1):6-11.
No abstract available.
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An experimental study on the stimulatory effects of epidermal growth factor and transforming growth factor-alpha on the growth of squamous cancer cell lines

Park YW

  • KMID: 2184118
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1998 Nov;20(4):334-340.
Stimulatory effects of epidermal growth factor(EGF) and transforming growth factor-alpha(TGF-alpha) on the growth of squamous cancer cell lines established from human oral cancer tissue with moderate differentiation were studied in...
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Menetrier's Disease: Its Mimickers and Pathogenesis

Huh WJ, Coffey RJ, Washington MK

Menetrier's disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Menetrier's disease is not fully understood; however, it...
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Stimulation of c-myc protooncogene expression by transforming growth factor a in human ovarian cancer cells

Choi JY, Hong YS, Park HY

  • KMID: 1532663
  • Exp Mol Med.
  • 1997 Dec;29(4):203-208.
To investigate whether transforming growth factor alpha (TGF alpha) treatment of human ovarian cancer cells was associated with the induction of c-myc protooncogene, the expression of this gene in NIH:OVCAR-3...
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Comparison of Transforming Growth Factor-alpha and Epidermal Growth Factor Expression in Melanocytic Nevi: An Immunohistochemical Study

Kang YS, Chung YY

  • KMID: 1559309
  • Korean J Anat.
  • 2002 Aug;35(4):261-268.
Transforming growth Factor-alpha(TGF-alpha) and epidermal growth factor (EGF) are polypeptides which interact with the epidermal growth factor receptor (EGFR) to produce its biological effects. In normal human tissues, its immunocytochemical...
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Expression of Epidermal Growth Factor, Transforming Growth Factor-alpha and Epidermal Growth Factor Receptor in Human Fallopian Tube at Various Menstrual Stages

Kwon DJ, Ryu SW, Kim MR, Chung KW, Kim CH, Lee JW

  • KMID: 2075813
  • Korean J Obstet Gynecol.
  • 1999 Jul;42(7):1422-1427.
OBJECTIVE: We studied the expression of epidermal growh factor[EGF] and transforming growth factor[TGF]-alpha and epidermal growth factor receptor[EGFR] in human fallopian tube at various menstrual stages. METHODS: To confirm the...
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Expression of Epidermal Growth Factor, Transforming Growth Factor-alpha and Epidermal Growth Factor Receptor in Human Cervical Neoplasia

Lee BH, Kwon DJ, Kim CJ, Kwon YI, Park TC, Kim JH, Lee JW, Kim DK, Namkoong S

  • KMID: 2270066
  • Korean J Obstet Gynecol.
  • 2001 Feb;44(2):273-276.
OBJECTIVE: This study seeks to define the expression of epidermal growth factor(EGF) and transforming growth factor(TGF)-alpha and epidermal growth factor receptor(EGFR), and the relationship to the tumor progression of human...
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Effect of Transforming Growth Factor-beta1 on Expressions of Epidermal Growth Factor and Transforming Growth Factor-alpha in DU145 Androgen-Independent Prostate Cancer Cells

Shin KY, Kong G, Choi HS, Lee JJ, Lee TY

  • KMID: 2292443
  • Korean J Urol.
  • 2001 Jan;42(1):40-46.
PURPOSE: This study was designed to identify the possible mechanism of insensitivity of DU145 prostate cancer cells to the transforming growth factor (TGF)-beta1-mediated growth inhibition. MATERIALS AND METHODS: DU145 cells were...
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A comparison Study of Expression of Transforming Growth factor - alpha in Keratoacanthomas and Squamous Cell Carcinomas

Park SK, Jang HS, Kwon KS, Chung TA

  • KMID: 1891562
  • Korean J Dermatol.
  • 1996 Apr;34(2):227-232.
BACKGROUND: Transforming growth factor-(TGF-alpha) is a acidic, heat-stable, 50 amino acid polypeptide which is related to cellular proliferation, malignant transformation, and angiogenesis. There are many similarities between keratoacanthoma(KA) and squamous...
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A Study in the Effects of Epidermal Growth Factor and Transforming Growth Factors-alpha on the Growth of Human Transitional Cell Carcinoma Cell Lines

Shin KY, Kim SJ, Choi WH, Choi DY, Park HY, Lee TY, Kong G, Woo YN, Kim DH

  • KMID: 2290025
  • Korean J Urol.
  • 1998 Jan;39(1):45-50.
PURPOSE: We evaluated the effects of epidermal growth factor(EGF) and transforming growth factor-alpha (TGF-alpha) on the growth of human transitional cell carcinoma cell lines. MATERIALS AND METHODS: T-24, KK47...
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Regulation of the apoptosis on the rat granulosa cell: effects of EGF, TGF-alpha

Jo HH, Hwang SJ, Kim HY, Kim MR, Kwon DJ, Kim JH, Kim JH

  • KMID: 2272479
  • Korean J Obstet Gynecol.
  • 2004 Dec;47(12):2439-2446.
OBJECTIVE: To evaluate the effect of the epidermal growth factor (EGF) and the transforming growth factor-alpha (TGF-alpha) on the apoptosis of the rat granulosa cells. METHODS: For this study, granulosa...
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Expression of Transforming Growth Factor-alpha and Transforming Growth Factor-beta In Human Primary Lung Cancers

Lew WJ, Shin DH, Park SS, Lee DH, Lee JD, Lee JH

  • KMID: 2317932
  • Tuberc Respir Dis.
  • 1995 Aug;42(4):492-501.
BACKGROUND: Transforming growth factor- alpha(TGF-alpha) may play important roles in carcinogenesis, tumor growth, and angiogenesis. Transforming growth factor-beta(TGF-beta) are known to be involved in cell-cycle control and regeneration. TGF-alpha positively...
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Immunocytochemical Localization of Transforming Growth Factor-alpha in the Forebrain of the Rat

Chung YY, Park SS, Yoon SP, Kim JJ, Moon JS, Jeong SB, Kim HS

  • KMID: 1558768
  • Korean J Anat.
  • 2001 Dec;34(6):589-602.
The distribution of Transforming growth factor-alpha (TGF-alpha) was examined in the rat forebrain by immunocytochemistry. TGF-alpha immunoreactivity was observed in the cerebral hemispheres, thalamus and hypothalamus. Neurons in the olfactory...
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Expression of TGF-alpha, beta1, beta2 in Pterygial Mast cell

Kim TH, Seo SW, Song JK

  • KMID: 2206119
  • J Korean Ophthalmol Soc.
  • 2002 Jul;43(7):1261-1268.
PURPOSE: To evaluate whether TGF-alpha, beta1, beta2 are expressed in pterygial mast cell and the difference between each growth factor exists. METHODS: We prepared 10 pieces each of excised normal conjunctiva,...
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Clinical Significance of Expression of Epidermal Growth Factor, Epidermal Growth Factor Receptor, Transforming Growth Factor-alpha in Aural Cholesteatoma

Kim JH, Kim HJ, Shin HS, Cho HC

  • KMID: 2274562
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Apr;42(4):416-422.
BACKGROUND AND OBJECTIVES: Aural cholesteatoma is characterized by hyperproliferation of keratinizing squamous epithelium in the middle ear cleft. Although the exact mechanism of bone destruction in aural cholesteatoma is still...
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Expression of Epidermal Growth Factor Related Peptides, EGF-R, and c-erbB-2 and Their Relationship with the Prognostic Factors in Gastric Carcinoma

Kim JH, Lee JW, Moon WS, Kang MJ, Lee DG

  • KMID: 2275682
  • Korean J Pathol.
  • 1999 Nov;33(11):1039-1046.
Recent investigations have revealed that autocrine growth factors and their receptors are closely related and play an important role in controlling cancer cell growth. We performed an immunohistochemical study on...
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Postnatal Development of Transforming-growth factor-alpha Immunoreactivity in the Cerebral Cortex of the Rat

Chung YY, Kim HS, Kim JJ, Moon JS

  • KMID: 2224551
  • Korean J Anat.
  • 2000 Aug;33(4):393-405.
Transforming growth factor-alpha (TGF-alpha) induces the proliferation and differentiation of central nervous system (CNS) as well as the survival and differentiation of postmitotic CNS neurons. Previous studies have mainly focused...
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Transforming Growth Factor-alpha Regulation of Insulin-like Growth Factor-II, Insulin-like Growth Factor Binding Protein-1 and 3 secretion and Epidermal Growth Factor receptor expression in human luteinized granulosa cells

Kang EH, Hong SH, Cho JS, Kim SH, Chae HD, Kim CH, Kang BM, Nam JH

  • KMID: 2270618
  • Korean J Obstet Gynecol.
  • 2002 Dec;45(12):2130-2139.
OBJECTIVE: To investigate the effects of transforming growth factor (TGF)-alpha on insulin-like growth factor (IGF)-II, insulin-like growth factor binding protein (IGFBP)-1, and 3 secretion and epidermal growth factor (EGF) receptor...
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Immunohistochemical Study for Epidermal Growth Factor Receptor and Transforming Growth Factor Alpha in Transitional Cell Carcinoma of the Urinary Bladder

Lew JH, Woo YN

  • KMID: 2139380
  • Korean J Urol.
  • 1994 Jul;35(7):697-706.
To evaluate the role of epidermal growth factor receptor(EGF-R) and transforming growth factor alpha (TGF-alpha) in transitional cell carcinoma of the urinary bladder, immunohistochemical studies using monoclonal antibodies to the...
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Menetrier's Disease Report of two cases

Kim JH, Lee DG, Juhng SW

  • KMID: 1921820
  • Korean J Pathol.
  • 1998 Feb;32(2):142-146.
Menetrier's disease is characterized by enlarged gastric folds with foveolar hyperplasia and cystic dilatation of gastric glands. The additional biochemical features of hypoproteinemia, hypochlorhydria, and increased gastric mucus are often...
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