- HPV-18 E7 Interacts with Elk-1 Leading to Elevation of the Transcriptional Activity of Elk-1 in Cervical Cancer
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Go SH, Rho SB, Yang DW, Kim BR, Lee CH, Lee SH
- KMID: 2534710
- Biomol Ther.
- 2022 Nov;30(6):593-602.
- doi: 10.4062/biomolther.2022.108
The human papillomavirus (HPV)-18 E7 (E7) oncoprotein is a major transforming protein that is thought to be involved in the development of cervical cancer. It is well-known that E7 stimulates... -
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- Interaction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M
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Lim J, Choi JH, Park EM, Choi YH
- KMID: 2502502
- Korean J Physiol Pharmacol.
- 2020 May;24(3):203-212.
- doi: 10.4196/kjpp.2020.24.3.203
Promyelocytic leukemia (PML) gene, through alternative splicing of its Cterminal region, generates several PML isoforms that interact with specific partners and perform distinct functions. The PML protein is a tumor... -
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- Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells
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Lee MH, Kundu JK, Keum YS, Cho YY, Surh YJ, Choi BY
- KMID: 2380320
- Biomol Ther.
- 2014 Sep;22(5):426-430.
- doi: 10.4062/biomolther.2014.061
Prostate cancer is the most frequently diagnosed cancer. Although prostate tumors respond to androgen ablation therapy at an early stage, they often acquire the potential of androgen-independent growth. Elevated transcriptional... -
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- Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications
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Kim TH, Kim MY, Jo SH, Park JM, Ahn YH
- KMID: 1727863
- Yonsei Med J.
- 2013 May;54(3):545-559.
- doi: 10.3349/ymj.2013.54.3.545
Peroxisome proliferator-activated receptor gamma (PPARgamma) belongs to a nuclear receptor superfamily; members of which play key roles in the control of body metabolism principally by acting on adipose tissue. Ligands... -
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- Relationship between Chromatin Pattern of Tumor Cell Nuclei and Transcriptional Sites
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Juhng SW
- KMID: 2172304
- Chonnam Med J.
- 2005 Dec;41(3):253-258.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- The effect of growth factor receptor HER2 on the estrogen receptor transcriptional activities and its implications
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Heo MK, Park SO, Jung SY, Kim SI, Park BW
- KMID: 2174951
- J Breast Cancer.
- 2005 Sep;8(3):105-112.
- doi: 10.4048/jbc.2005.8.3.105
PURPOSE: Until recently, breast cancer carcinogenesis has not been fully understood, but the roles of estrogen receptors(ERs) and growth factor receptors(like HER2) were known to be important. Growth factors have... -
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