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Toxicological Investigation of Radioactive Uranium in Seawater

Ly SY, Bae JM, Kim J

  • KMID: 2052553
  • Toxicol Res.
  • 2012 Mar;28(1):67-71.
Trace uranium detection measurement was performed using DNA immobilized on a graphite pencil electrode (DGE). The developed probe was connected to the portable handheld voltammetric systems used for seawater analysis....
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The Safety Evaluation of a Potent Angiogenic Activator, Synthetic Peptide (SFKLRY-NH2) for the Skin Application

Kim DH, Lim YY, Kim HM, Kim SY, Kim BJ, Park SG, Lee T, Cho SM

  • KMID: 2052551
  • Toxicol Res.
  • 2012 Mar;28(1):51-56.
A novel synthetic hexapeptide (SFKLRY-NH2) that displays angiogenic activity has been identified by positional scanning of a synthetic peptide combinatorial library (PS-SPCL). This study was carried out to investigate the...
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Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro

Kang MR, Lee CW, Yun J, Oh SJ, Park SK, Lee K, Kim HM, Han SB, Kim HC, Kang JS

  • KMID: 2052549
  • Toxicol Res.
  • 2012 Mar;28(1):33-38.
In this study, we investigated the effect of methanolic extract isolated from the root of Lycoris aurea (LA) on the growth of cancer cells and the tube formation activity of...
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Involvement of Caenohabditis elegans MAPK Signaling Pathways in Oxidative Stress Response Induced by Silver Nanoparticles Exposure

Roh JY, Eom HJ, Choi J

  • KMID: 2052547
  • Toxicol Res.
  • 2012 Mar;28(1):19-24.
In the present study, toxicity of silver nanoparticles (AgNPs) was investigated in the nematode, Caenohabditis elegans focusing on the upstream signaling pathway responsible for regulating oxidative stress, such as mitogen-activated...
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Synthetic Prion Peptide 106-126 Resulted in an Increase Matrix Metalloproteinases and Inflammatory Cytokines from Rat Astrocytes and Microglial Cells

Song K, Na JY, Oh MH, Kim S, Kim YH, Park BY, Shin GW, Kim B, You M, Kwon J

  • KMID: 2052545
  • Toxicol Res.
  • 2012 Mar;28(1):5-9.
It has been shown that the accumulation of prion in the cytoplasm can result in neurodegenerative disorders. Synthetic prion peptide 106-126 (PrP) is a glycoprotein that is expressed predominantly by...
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Skin Sensitization Study of Bee Venom (Apis mellifera L.) in Guinea Pigs

Han SM, Lee GG, Park KK

  • KMID: 2052544
  • Toxicol Res.
  • 2012 Mar;28(1):1-4.
Bee venom (Apis mellifera L., BV) has been used as a cosmetic ingredient for antiaging, anti-inflammatory and antibacterial functions. The aim of this study was to access the skin sensitization...
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Mouse Single Oral Dose Toxicity Test of Bupleuri Radix Aqueous Extracts

Kim KH, Gam CO, Choi SH, Ku SK

  • KMID: 2052546
  • Toxicol Res.
  • 2012 Mar;28(1):11-18.
The aim of this study was to evaluate the single oral dose toxicity of Bupleuri Radix (BR) aqueous extracts, it has been traditionally used as anti-inflammatory agent, in male and...
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The Toxicity and Anti-cancer Activity of the Hexane Layer of Melia azedarach L. var. japonica Makino's Bark Extract

Kim HW, Kang SC

  • KMID: 2052552
  • Toxicol Res.
  • 2012 Mar;28(1):57-65.
In this study, the 4-week oral toxicity and anti-cancer activity of the hexane layer of Melia azedarach L. var. japonica Makino's bark extract were investigated. We carried out a hollow...
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Acute Pulmonary Toxicity and Body Distribution of Inhaled Metallic Silver Nanoparticles

Kwon JT, Minai-Tehrani A, Hwang SK, Kim JE, Shin JY, Yu KN, Chang SH, Kim DS, Kwon YT, Choi IJ, Cheong YH, Kim JS, Cho MH

  • KMID: 2052548
  • Toxicol Res.
  • 2012 Mar;28(1):25-31.
The purpose of this study was to determine the acute pulmonary toxicity of metallic silver nanoparticles (MSNPs, 20.30 nm in diameter). Acute pulmonary toxicity and body distribution of inhaled MSNPs...
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Suppressive Effect of Zinc on the Formation of Colonic Preneoplastic Lesions in the Mouse Fed High Levels of Dietary Iron

Park H, Kang BS, Kim DY, Yoon JS, Jeong JH, Nam SY, Yun YW, Kim JS, Lee BJ

  • KMID: 2052550
  • Toxicol Res.
  • 2012 Mar;28(1):39-49.
We investigated the effect of zinc on the formation of colonic aberrant crypt foci induced by azoxymethane (AOM) followed by dextran sodium sulfate (DSS) in mice with high iron diet...
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