- Bioengineering Approaches for Corneal Regenerative Medicine
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Mahdavi SS, Abdekhodaie MJ, Mashayekhan S, Baradaran-Rafii A, Djalilian AR
- KMID: 2507309
- Tissue Eng Regen Med.
- 2020 Oct;17(5):567-593.
- doi: 10.1007/s13770-020-00262-8
BACKGROUND: Since the cornea is responsible for transmitting and focusing light into the eye, injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual... -
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- Effect of Integrin Binding Peptide on Vascularization of Scaffold-Free Microtissue Spheroids
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Yaralı ZB, Onak G, Karaman O
- KMID: 2507312
- Tissue Eng Regen Med.
- 2020 Oct;17(5):595-605.
- doi: 10.1007/s13770-020-00281-5
BACKGROUND: Three-dimensional (3D) biomimetic models via various approaches can be used by therapeutic applications of tissue engineering. Creating an optimal vascular microenvironment in 3D model that mimics the extracellular matrix... -
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- Combined Delivery of Two Different Bioactive Factors Incorporated in Hydroxyapatite Microcarrier for Bone Regeneration
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Kim TW, Ahn WB, Kim JM, Kim JH, Kim TH, Perez RA, Jang HS
- KMID: 2507313
- Tissue Eng Regen Med.
- 2020 Oct;17(5):607-624.
- doi: 10.1007/s13770-020-00257-5
BACKGROUND: The delivery of growth factors using a carrier system presents a promising and innovative tool in tissue engineering and dentistry today. Two of the foremost bioactive factors, bone morphogenetic... -
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- Erythropoietin-Modified Mesenchymal Stem Cells Enhance Antifibrosis Efficacy in Mouse Liver Fibrosis Model
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Wang X, Wang H, Lu J, Feng Z, Liu Z, Song H, Wang H, Zhou Y, Xu J
- KMID: 2507324
- Tissue Eng Regen Med.
- 2020 Oct;17(5):683-693.
- doi: 10.1007/s13770-020-00276-2
BACKGROUND: Mesenchymal stem cell (MSC)-based cell transplantation is an effective means of treating chronic liver injury, fibrosis and end-stage liver disease. However, extensive studies have found that only a small... -
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- Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver
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Kao YH, Lin YC, Lee PH, Lin CW, Chen PH, Tai TS, Chang YC, Chou MH, Chang CY, Sun CK
- KMID: 2507320
- Tissue Eng Regen Med.
- 2020 Oct;17(5):671-682.
- doi: 10.1007/s13770-020-00274-4
BACKGROUND: This study investigated whether xenotransplantation of human Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) reduces thioacetamide (TAA)-induced mouse liver fibrosis and the underlying molecular mechanism. METHODS: Recipient NOD/SCID mice were injected... -
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- Irregular Bone Defect Repair Using Tissue-Engineered Periosteum in a Rabbit Model
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Zhao L, Zhao J, Yu JJ, Zhang C
- KMID: 2507337
- Tissue Eng Regen Med.
- 2020 Oct;17(5):717-727.
- doi: 10.1007/s13770-020-00282-4
BACKGROUND: In previous studies, we succeeded in repairing a long bone defect with tissue-engineered periosteum (TEP), fabricated by incorporating rabbit mesenchymal stem cells with small intestinal submucosa. In this study,... -
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- Evaluation of Intestinal Epithelial Barrier Function in Inflammatory Bowel Diseases Using Murine Intestinal Organoids
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Rallabandi HR, Yang H, Oh KB, Lee HC, Byun SJ, Lee BR
- KMID: 2507315
- Tissue Eng Regen Med.
- 2020 Oct;17(5):641-650.
- doi: 10.1007/s13770-020-00278-0
BACKGROUND: Intestinal organoids have evolved as potential molecular tools that could be used to study host-microbiome interactions, nutrient uptake, and drug screening. Gut epithelial barrier functions play a crucial role... -
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- Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/ PAWR Axis
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Chai Q, Zheng M, Wang Z, We M, Yin Y, Ma F, Li X, Zhang H, Liu G
- KMID: 2507318
- Tissue Eng Regen Med.
- 2020 Oct;17(5):659-670.
- doi: 10.1007/s13770-020-00270-8
BACKGROUND: The cardiomyocyte apoptosis is considered as one of major contributions to cardiac remodeling after myocardial infarction (MI). Numerous studies find that circular RNAs (circRNAs) play pivotal roles in a... -
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- Promoting Osseointegration of Dental Implants in Dog Maxillary Sinus Floor Augmentation Using Dentin Matrix Protein 1-Transduced Bone Marrow Stem Cells
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Ma D, Wang Y, Chen Y, Yang G, Liu X
- KMID: 2507328
- Tissue Eng Regen Med.
- 2020 Oct;17(5):705-715.
- doi: 10.1007/s13770-020-00277-1
BACKGROUND: Beta-tricalcium phosphate ( β-TCP) has been employed successfully as a synthetic graft material in maxillary sinus floor augmentation (MSFA) for placing dental implants. However, the lack of osteogenic and... -
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- Hyaluronic Acid/Alginate Hydrogel Containing Hepatocyte Growth Factor and Promotion of Vocal Fold Wound Healing
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Choi JS, Oh SH, Kim YM, Lim JY
- KMID: 2507316
- Tissue Eng Regen Med.
- 2020 Oct;17(5):651-658.
- doi: 10.1007/s13770-020-00280-6
BACKGROUND: Hepatocyte growth factor (HGF) has been shown to facilitate vocal fold (VF) wound healing. This study was undertaken to determine whether the therapeutic efficacy of HGF could be enhanced... -
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- Inhibitory Effect of Topical Cartilage Acellular Matrix Suspension Treatment on Neovascularization in a Rabbit Corneal Model
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Yun HW, Choi BH, Park DY, Jin LH, Min BH
- KMID: 2507314
- Tissue Eng Regen Med.
- 2020 Oct;17(5):625-640.
- doi: 10.1007/s13770-020-00275-3
BACKGROUND: The extracellular matrix (ECM) of articular cartilage has an inhibitory effect on vascularization, yet clinical utilization has been technically challenging. In this study, we aimed to fabricate a biologically... -
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- Mannitol Augments the Effects of Systemical Stem Cell Transplantation without Increasing Cell Migration in a Stroke Animal Model
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Lee SH, Kang HY, Kim JH, Park DH
- KMID: 2507326
- Tissue Eng Regen Med.
- 2020 Oct;17(5):695-704.
- doi: 10.1007/s13770-020-00293-1
BACKGROUND: Mannitol increases blood–brain barrier permeability and can improve the efficiency of systemically administered stem cells by facilitating stem cell entry from the periphery into the injured brain. The aim... -
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