- Comparison of Angiogenic Activities of Three Neuropeptides, Substance P, Secretoneurin, and Neuropeptide Y Using Myocardial Infarction
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Lee J, Song M, Kim J, Park Y
- KMID: 2418105
- Tissue Eng Regen Med.
- 2018 Aug;15(4):493-502.
- doi: 10.1007/s13770-018-0134-x
BACKGROUND: The interplay between neurogenesis and angiogenesis is crucial during the development mediated by neuro-angiogenic morphogens. In particular, the angiogenic activity of neuropeptides and their role in tissue regeneration have... -
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- Fabrication of Microchannels and Evaluation of Guided Vascularization in Biomimetic Hydrogels
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Lee J, Lee SH, Lee BK, Park SH, Cho YS, Park Y
- KMID: 2418097
- Tissue Eng Regen Med.
- 2018 Aug;15(4):403-413.
- doi: 10.1007/s13770-018-0130-1
BACKGROUND: The fabrication of microchannels in hydrogel can facilitate the perfusion of nutrients and oxygen, which leads to guidance cues for vasculogenesis. Microchannel patterning in biomimetic hydrogels is a challenging... -
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- Wicking Property of Graft Material Enhanced Bone Regeneration in the Ovariectomized Rat Model
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Kim S, Ahn T, Han MH, Bae C, Oh DS
- KMID: 2418106
- Tissue Eng Regen Med.
- 2018 Aug;15(4):503-510.
- doi: 10.1007/s13770-018-0142-x
BACKGROUND: Recruitment and homing cells into graft materials from host tissue is crucial for bone regeneration. METHODS: Highly porous, multi-level structural, hydroxyapatite bone void filler (HA-BVF) have been investigated to restore... -
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- A 4-Axis Technique for Three-Dimensional Printing of an Artificial Trachea
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Park HS, Park HJ, Lee J, Kim P, Lee JS, Lee YJ, Seo YB, Kim DY, Ajiteru O, Lee OJ, Park CH
- KMID: 2418098
- Tissue Eng Regen Med.
- 2018 Aug;15(4):415-425.
- doi: 10.1007/s13770-018-0136-8
BACKGROUND: Several types of three-dimensional (3D)-printed tracheal scaffolds have been reported. Nonetheless, most of these studies concentrated only on application of the final product to an in vivo animal study... -
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- A Pathophysiological Validation of Collagenase II-Induced Biochemical Osteoarthritis Animal Model in Rabbit
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Park J, Lee J, Kim KI, Lee J, Jang S, Choi HT, Son Y, Kim HJ, Woo EJ, Lee E, Oh TI
- KMID: 2418100
- Tissue Eng Regen Med.
- 2018 Aug;15(4):437-444.
- doi: 10.1007/s13770-018-0124-z
BACKGROUND: Current dilemma working with surgically-induced OA (osteoarthritis) model include inconsistent pathological state due to various influence from surrounding tissues. On the contrary, biochemical induction of OA using collagenase II... -
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- The Use of Normal Stem Cells and Cancer Stem Cells for Potential Anti-Cancer Therapeutic Strategy
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Han SW, Kim YY, Kang WJ, Kim HC, Ku SY, Kang BC, Yun JW
- KMID: 2418094
- Tissue Eng Regen Med.
- 2018 Aug;15(4):365-380.
- doi: 10.1007/s13770-018-0128-8
BACKGROUND: Despite recent advance in conventional cancer therapies including surgery, radiotherapy, chemotherapy, and immunotherapy to reduce tumor size, unfortunately cancer mortality and metastatic cancer incidence remain high. Along with a... -
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- Mesenchymal Stem Cells of Different Origin-Seeded Bioceramic Construct in Regeneration of Bone Defect in Rabbit
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Maiti SK, Shivakumar MU, Mohan D, Kumar N, Singh KP
- KMID: 2418104
- Tissue Eng Regen Med.
- 2018 Aug;15(4):477-492.
- doi: 10.1007/s13770-018-0129-7
BACKGROUND: Stem cell is currently playing a major role in the treatment of number of incurable diseases via transplantation therapy. The objective of this study was to determine the osteogenic... -
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- In Vitro and In Vivo Osteogenesis of Human Orbicularis Oculi Muscle-Derived Stem Cells
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Liu G, Liao C, Chen X, Wu Y
- KMID: 2418101
- Tissue Eng Regen Med.
- 2018 Aug;15(4):445-452.
- doi: 10.1007/s13770-018-0122-1
BACKGROUND: Cell-based therapies for treating bone defects require a source of stem cells with osteogenic potential. There is evidence from pathologic ossification within muscles that human skeletal muscles contain osteogenic... -
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- Thermoresponsive and Biodegradable Amphiphilic Block Copolymers with Pendant Functional Groups
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Lee BK, Noh JH, Park JH, Park SH, Kim JH, Oh SH, Kim MS
- KMID: 2418096
- Tissue Eng Regen Med.
- 2018 Aug;15(4):393-402.
- doi: 10.1007/s13770-018-0121-2y
BACKGROUND: To develop the biodegradability and thermoresponsive hydrogel, in this work we designed a pendant-functionalized, thermoresponsive, amphiphilic block copolymer. METHODS: Methoxy poly(ethylene glycol) (MPEG)-b-[poly(ε-caprolactone)-ran-poly(ε-caprolactone-3-one)-ran-polylactic acid] (MCL) and (MPEG-b-[PCL-ran-POD-ran-PLA]) [MCL-(CO)] block copolymers... -
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- Three-Dimensional Spheroid Culture Increases Exosome Secretion from Mesenchymal Stem Cells
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Kim M, Yun HW, Park DY, Choi BH, Min BH
- KMID: 2418099
- Tissue Eng Regen Med.
- 2018 Aug;15(4):427-436.
- doi: 10.1007/s13770-018-0139-5
BACKGROUND: Mass production of exosomes is a prerequisite for their commercial utilization. This study investigated whether three-dimensional (3D) spheroid culture of mesenchymal stem cells (MSCs) could improve the production efficiency... -
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- Positive Effects of Bisphosphonates on Osteogenic Differentiation in Patient-Derived Mesenchymal Stem Cells for the Treatment of Osteoporosis
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Cha M, Lee KM, Lee JH
- KMID: 2418103
- Tissue Eng Regen Med.
- 2018 Aug;15(4):467-475.
- doi: 10.1007/s13770-018-0127-9
BACKGROUND: Recent evidence from in vitro and in vivo studies indicates that bisphosphonates may promote osteoblastic bone formation and potently inhibit osteoclast activity. However, little is known about the potential... -
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- In Vivo Validation Model of a Novel Anti-Inflammatory Scaffold in Interleukin-10 Knockout Mouse
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Kim JY, Chun SY, Lee SH, Lih E, Kim J, Kim DH, Ha YS, Chung JW, Lee JN, Kim BS, Kim HT, Yoo ES, Han DK, Kwon TG, Jang BI
- KMID: 2418095
- Tissue Eng Regen Med.
- 2018 Aug;15(4):381-392.
- doi: 10.1007/s13770-018-0120-3
BACKGROUND: We fabricated anti-inflammatory scaffold using Mg(OH)2-incorporated polylactic acid-polyglycolic acid copolymer (MH-PLGA). To demonstrate the anti-inflammatory effects of the MH-PLGA scaffold, an animal model should be sensitive to inflammatory responses.... -
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- A Novel Dorsal Slit Approached Non-Ischemic Partial Nephrectomy Method for a Renal Tissue Regeneration in a Mouse Model
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Chun SY, Kim DH, Kim JS, Kim HT, Yoo ES, Chung JW, Ha YS, Song PH, Joung YK, Han DK, Chung SK, Kim BS, Kwon TG
- KMID: 2418102
- Tissue Eng Regen Med.
- 2018 Aug;15(4):453-466.
- doi: 10.1007/s13770-018-0123-0
BACKGROUND: Kidney ischemia-reperfusion (IR) via laparotomy is a conventional method for kidney surgery in a mouse model. However, IR, an invasive procedure, can cause serious acute and chronic complications through... -
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