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Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes

Jin GZ, Kim HW

It is controversial whether type I collagen itself can maintain and improve chondrogenic phenotype of chondrocytes in a three-dimensional (3D) environment. In this study, we examined the effect of type...
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Co-culture of Human Dental Pulp Stem Cells and Endothelial Cells Using Porous Biopolymer Microcarriers: A Feasibility Study for Bone Tissue Engineering

Jin GZ, Kim HW

Delivery of stem cells with osteogenesis while enabling angiogenesis is important for vascularized bone tissue engineering. Here a three-dimensional (3D) co-culture system of dental pulp stem cells (DPSCs) and endothelial...
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Dental Pulp Stem Cells: Current Advances in Isolation, Expansion and Preservation

Rodas-Junco BA, VillicanËœa C

Dental pulp stem cells (DPSCs) are mesenchymal stem cells with high self-renewal potential that have the ability to differentiate into several cell types. Thus, DPSCs have become a promising source...
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Multilayered Engineered Tissue Sheets for Vascularized Tissue Regeneration

Hong S, Jung BY, Hwang C

A major hurdle in engineering thick and laminated tissues such as skin is how to vascularize the tissue. This study introduces a promising strategy for generatingmulti-layering engineered tissue sheets consisting...
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Low-Dose Ionizing γ-Radiation Promotes Proliferation of Human Mesenchymal Stem Cells and Maintains Their Stem Cell Characteristics

Cho W, Kim ES, Kang CM, Ji YH, Kim JI, Park SJ, Son Y, Kim CH

Mesenchymal stem cells (MSCs), which are multipotent and have self-renewal ability, support the regeneration of damaged normal tissue. A number of external stimuli promote migration of MSCs into peripheral blood...
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Erratum to: Characteristics and Cardiomyogenic Potential of RatFetal Cardiac Progenitor Cells at Different Developmental Stage

Thanh TN, Shin HC, Kim HR, Park SR, Kim J, Choi BH

There are some errors in the published article. The authors would like to make corrections in the original version of the article
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Effects of Trichostatin A on the Chondrogenesis from Human Mesenchymal Stem Cells

Lee J, Im GI

Histone deacetylase inhibitors (HDACi) are a class of compounds that suppress the function of histone deacetylases (HDACs). This study was performed to examine the effects of Trichostatin A (TSA), a...
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Erratum to: Autologous Bone-marrow Mesenchymal Cell induced Chondrogenesis: Single-stage Arthroscopic Cartilage Repair

Ananthram Shetty A, Kim SJ, Shetty V, Stelzeneder D, Shetty N, Bilagi P, Lee HJ

There was an error in Fig. 3 caption of the originally published article. Please find the correct figure and caption in this erratum
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PCL/β-TCP Composite Scaffolds Exhibit Positive Osteogenic Differentiation with Mechanical Stimulation

Park SH, Park SA, Kang YG, Shin JW, Park YS, Gu SR, Wu YR, Wei J, Shin JW

We investigated the use of Polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) composites with applied mechanical stimulation as scaffold for bone tissue engineering. PCL-based three-dimensional (3D) structures were fabricated in a solvent-free process...
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Appropriate Tensile Mode and Timing of Applying Tension to Promote Tendon Gel Regeneration

Kuzumaki T, Yamazaki K, Suzuki K, Torigoe K

“Tendon gel” secreted from a parent tendon is regenerated for tendon repair by applying tension. However, the details of the tensile stimulus have not been clarified. This study aimed to...
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Endothelial Progenitor Cells' Classification and Application in Neurological Diseases

Yuan JJ, Yang J, Sun SL, Zhang R, Xu YM

The therapeutic effects of endothelial progenitor cells (EPCs) on ischemic stroke have been extensively studied in recent years. However, the differences in early EPCs and endothelial outgrowth cells (EOCs) are...
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Clean-Up Human Embryonic Stem Cell Lines Using Humanized Culture Condition

Baek JA, Seol HW, Jung J, Kim HS, Oh SK, Choi YM

Human embryonic stem cell (hESC) culture system has been changing culture conditions from conventional to xeno-free for therapeutic cell applications, and N-glycolylneuraminic acid (Neu5Gc) could be a useful indicator of...
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Recombinant human bone morphogenic protein-2 Induces the Differentiation and Mineralization of Osteoblastic Cells Under Hypoxic Conditions via Activation of Protein Kinase D and p38 Mitogen-Activated Protein Kinase Signaling Pathways

Ha WH, Seong HS, Choi NR, Park BS, Kim YD

Hypoxia suppresses osteoblastic differentiation and the bone-forming capacity. As the leading osteoinductive growth factor used clinically in bone-related regenerative medicine, recombinant human bone morphogenic protein-2 (rhBMP- 2) has yielded promising...
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Intracellular Remodeling and Accumulation of Aberrant Lysosomes in Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Parathyroid-Like Cells

Jo YI, Kim G, Jin YM, Park YJ, Kim HS, Park YS

Differentiation of mesenchymal stem cells (MSC) into a variety of cell lineages such as adipocytes, osteocytes, and chondrocytes is often accompanied up-regulation of autophagy. In our study, we demonstrated that...
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Heparin/Collagen 3D Scaffold Accelerates Hepatocyte Differentiation of Wharton's Jelly-Derived Mesenchymal Stem Cells

Aleahmad F, Ebrahimi S, Salmannezhad M, Azarnia M, Jaberipour M, Hoseini M, Talaei-Khozani T

Both mature and stem cell-derived hepatocytes lost their phenotype and functionality under conventional culture conditions. However, the 3D scaffolds containing the main extracellular matrix constitutions, such as heparin, may provide...
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Surface Coating of Polytetrafluoroethylene with Extracellular Matrix and Anti-CD34 Antibodies Facilitates Endothelialization and Inhibits Platelet Adhesion Under Sheer Stress

Chen L, He H, Wang M, Li X, Yin H

Expanded polytetrafluoroethylene (ePTFE) polymers do not support endothelialization because of nonconductive characteristics towards cellular attachment. Inner surface modification of the grafts can improve endothelialization and increase the long-term patency rate...
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