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Rare PTH Gene Mutations Causing Parathyroid Disorders: A Review

Lee JH, Davaatseren M, Lee S

Since parathyroid hormone (PTH) was first isolated and its gene (PTH) was sequenced, only eight PTH mutations have been discovered. The C18R mutation in PTH, discovered in 1990, was the...
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The Association between Low Vitamin D Status and Autoimmune Thyroid Disease in Korean Premenopausal Women: The 6th Korea National Health and Nutrition Examination Survey, 2013–2014

Kim CY, Lee YJ, Choi JH, Lee SY, Lee HY, Jeong DH, Choi YJ

BACKGROUND: This study aimed to analyze the association of low vitamin D status with thyroid autoimmunity and dysfunction in the Korean population according to sex and menopausal status in women. METHODS:...
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Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata

Zhang L, Xu X, Chen S, Kang Y, Wang X, Zhang C, Xiang L

BACKGROUND: Vitiligo is a common acquired pigmentary disease caused by destruction of epidermal melanocytes in underlying autoimmune response. Few studies have been focused on the role of chemokines in non-segmental...
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Natural Killer Cells and Thyroid Diseases

Lee EK, Sunwoo JB

Abnormal production of thyroid hormone is one of the common endocrine disorders, and thyroid hormone production declines with age. The aging process also negatively affects the immune system. An interaction...
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Digital Medicine in Thyroidology: A New Era of Managing Thyroid Disease

Moon JH, Steinhubl

Digital medicine has the capacity to affect all aspects of medicine, including disease prediction, prevention, diagnosis, treatment, and post-treatment management. In the field of thyroidology, researchers are also investigating potential...
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High-intensity focused ultrasound ablation as a treatment for benign thyroid diseases: the present and future

Kotewall N, Lang BH

High-intensity focused ultrasound (HIFU) is a promising ablation technique for benign thyroid nodules. Current evidence has found good short- to medium-term outcomes, similar to those of better-established ablation techniques such...
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Percutaneous laser ablation for benign and malignant thyroid diseases

Mauri G, Nicosia L, Della vigna P, Varano GM, Maiettini , Bonomo G, Giuliano G, Orsi F, Solbiati L, De fiori E, Papini E, Pacella CM, Sconfienza LM

Minimally invasive image-guided thermal ablation is becoming increasingly common as an alternative to surgery for the treatment of benign thyroid nodules. Among the various techniques for thermal ablation, laser ablation...
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Preliminary study on the efficacy of xerostomia treatment with sialocentesis targeting thyroid disease patients given radioiodine therapy

Kim EH, Lee DK, Kim CW, Song IS, Jun SH

BACKGROUND: Radioiodine therapy has been widely used for thyroid disease patients, but hyposalivation and xerostomia may occur in 10~30% of patients. Sialocentesis is a procedure that removes inflammatory substances in...
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Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study

Kwon H, Jung JH, Han KD, Park YG, Cho JH, Lee DY, Han JM, Park SE, Rhee EJ, Lee WY

BACKGROUND: The incidence of thyroid nodules has increased worldwide in recent years. Thyroid dysfunction is a potential risk factor for hypercholesterolemia, cardiovascular disease, osteoporosis, arrhythmia, and neuropsychiatric disease. This study...
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Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer

Hwangbo Y, Park YJ

Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development...
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Increased Risk of Chronic Spontaneous Urticaria in Patients With Autoimmune Thyroid Diseases: A Nationwide, Population-based Study

Kim YS, Han K, Lee JH, Kim NI, Roh JY, Seo SJ, Song HJ, Lee MG, Choi JH, Park YM

There was no previous population-based study on the comparison of the risk of chronic spontaneous urticaria (CSU) between autoimmune thyroid diseases (AITD) and age- and gender-matched controls. The primary objective...
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High Prevalence of Thyroid Disease and Role of Salivary Gland Scintigraphy in Patients with Xerostomia

Jung JH, Lee CH, Son SH, Jeong JH, Jeong SY, Lee SW, Lee J, Ahn BC

PURPOSE: Although Sjögren's syndrome (SS) is the most common disease causing xerostomia, autoimmune thyroid diseases can also affect the salivary glands. The aim of our study was to estimate the...
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Ultrasonographic Evaluation of Diffuse Thyroid Disease: a Study Comparing Grayscale US and Texture Analysis of Real-Time Elastography (RTE) and Grayscale US

Yoon JH, Lee E, Lee HS, Kim EK, Moon HJ, Kwak JY

BACKGROUND AND OBJECTIVES: To evaluate and compare the diagnostic performances of grayscale ultrasound (US) and quantitative parameters obtained from texture analysis of grayscale US and elastography images in evaluating patients...
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Routine calcitonin measurement in nodular thyroid disease management: is it worthwhile?

Turk Y, Makay O, Ozdemir M, Ertunc G, Demir B, Icoz G, Akyildiz M, Yilmaz M

PURPOSE: To evaluate the diagnostic accuracy of routine calcitonin measurement in patients with nodular thyroid disease. METHODS: Consecutive patients with nodular thyroid disease (n = 640) were studied. Serum calcitonin levels...
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The Relationship between Subclinical Thyroid Disease and Cardiovascular Disease Risk Score in Koreans

Lim HJ, Ahn SH, Hong S, Suh YJ

Subclinical hyperthyroidism and subclinical hypothyroidism are characterized by abnormal thyroid stimulating hormone (TSH) with normal free thyroxine. Subclinical thyroid diseases, to date, have received less attention compared with other thyroid...
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Thyroid disease in children and adolescents

Hong HS, Lee JY, Jeong SH

No abstract available.
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Serum vitamin D3 levels are not associated with thyroid cancer prevalence in euthyroid subjects without autoimmune thyroid disease

Choi YM, Kim WG, Kim TY, Bae SJ, Kim HK, Jang EK, Jeon MJ, Han JM, Shong YK, Kim WB

BACKGROUND/AIMS: Previous studies have suggested that elevated serum vitamin D levels might protect against thyroid cancer. Elevated serum thyroid stimulating hormone levels and autoimmune thyroid disease (AITD) are suggested to...
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Update on the Management of Thyroid Disease during Pregnancy

Yim CH

Thyroid dysfunction during pregnancy can result in serious complications for both the mother and infant; however, these complications can be prevented by optimal treatment of maternal overt thyroid dysfunction. Although...
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Recent Advances in Autoimmune Thyroid Diseases

Yoo WS, Chung HK

Autoimmune thyroid disease (AITD) includes hyperthyroid Graves disease, hypothyroid autoimmune thyroiditis, and subtle subclinical thyroid dysfunctions. AITD is caused by interactions between genetic and environmental predisposing factors and results in...
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Clinical Relevance of Environmental Factors in the Pathogenesis of Autoimmune Thyroid Disease

Wiersinga

Genetic factors contribute for about 70% to 80% and environmental factors for about 20% to 30% to the pathogenesis of autoimmune thyroid disease (AITD). Relatives of AITD patients carry a...
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