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11 results

Retraction notice to: Myosin VI contributes to malignant proliferation of human glioma cells

Xu R, Fang XH, Zhong P

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):565-565.
  • doi: 10.4196/kjpp.2017.21.5.565
The Editors of Korean J Physiol Pharmacol have informed that this article may include the results of experiments that were not performed by the authors. All authors have agreed that...
The advantage of topographic prominence-adopted filter for the detection of short-latency spikes of retinal ganglion cells

Ahn J, Choi MH, Kim K, Senok SS, Cho DI, Koo KI, Goo Y

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):555-563.
  • doi: 10.4196/kjpp.2017.21.5.555
Electrical stimulation through retinal prosthesis elicits both short and long-latency retinal ganglion cell (RGC) spikes. Because the short-latency RGC spike is usually obscured by electrical stimulus artifact, it is very...
Hydroquinone suppresses IFN-β expression by targeting AKT/IRF3 pathway

Kim Y, Kim HG, Han SY, Jeong D, Yang WS, Kim JI, Kim JH, Yi YS, Cho JY

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):547-554.
  • doi: 10.4196/kjpp.2017.21.5.547
Previous studies have demonstrated the role of hydroquinone (HQ), a hydroxylated benzene metabolite, in modulating various immune responses; however, its role in macrophage-mediated inflammatory responses is not fully understood. In...
Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins

Ha SH, Kim HK, Anh NT, Kim N, Ko KS, Rhee BD, Han J

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):531-546.
  • doi: 10.4196/kjpp.2017.21.5.531
Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and...
Sodium butyrate has context-dependent actions on dipeptidyl peptidase-4 and other metabolic parameters

Lee ES, Lee DS, Pandeya PR, Kim YC, Kang DG, Lee HS, Oh BC, Lee DH

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):519-529.
  • doi: 10.4196/kjpp.2017.21.5.519
Sodium butyrate (SB) has various metabolic actions. However, its effect on dipeptidyl peptidase 4 (DPP-4) needs to be studied further. We aimed to evaluate the metabolic actions of SB, considering...
Effect of glucose level on chemical hypoxia- and hydrogen peroxide-induced chemokine expression in human glioblastoma cell lines

Jung Y, Ahn SH, Park SH, Choi YH

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):509-518.
  • doi: 10.4196/kjpp.2017.21.5.509
Glioblastoma multiforme (GBM) is the most common primary intracranial tumor in adults and has poor prognosis. The GBM-specific tumor microenvironment (TME) plays a crucial role in tumor progression, immune escape,...
The activation of α₂-adrenergic receptor in the spinal cord lowers sepsis-induced mortality

Kim SS, Park SH, Lee JR, Jung JS, Suh HW

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):495-507.
  • doi: 10.4196/kjpp.2017.21.5.495
The effect of clonidine administered intrathecally (i.t.) on the mortality and the blood glucose level induced by sepsis was examined in mice. To produce sepsis, the mixture of D-galactosamine (GaLN;...
Inhibition of anterior cingulate cortex excitatory neuronal activity induces conditioned place preference in a mouse model of chronic inflammatory pain

Kang SJ, Kim S, Lee J, Kwak C, Lee K, Zhuo M, Kaang BK

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):487-493.
  • doi: 10.4196/kjpp.2017.21.5.487
The anterior cingulate cortex (ACC) is known for its role in perception of nociceptive signals and the associated emotional responses. Recent optogenetic studies, involving modulation of neuronal activity in the...
RhGLP-1 (7–36) protects diabetic rats against cerebral ischemia-reperfusion injury via up-regulating expression of Nrf2/HO-1 and increasing the activities of SOD

Fang Y, Liu X, Zhao L, Wei Z, Jiang D, Shao H, Zang Y, Xu J, Wang Q, Liu Y, Peng Y, Yin X

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):475-485.
  • doi: 10.4196/kjpp.2017.21.5.475
The present study aimed to explore the neuroprotective effect and possible mechanisms of rhGLP-1 (7–36) against transient ischemia/reperfusion injuries induced by middle cerebral artery occlusion (MCAO) in type 2 diabetic...
Resveratrol raises in vitro anticancer effects of paclitaxel in NSCLC cell line A549 through COX-2 expression

Kong F, Zhang R, Zhao X, Zheng G, Wang Z, Wang P

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):465-474.
  • doi: 10.4196/kjpp.2017.21.5.465
The aim of this study was to determine the raising anticancer effects of resveratrol (Res) on paclitaxel (PA) in non-small cell lung cancer (NSCLC) cell line A549. The 10 µg/ml...
Effect of etoricoxib on experimental oxidative testicular ischemia-reperfusion damage in rats induced with torsion-detorsion

Yapanoglu , Ozkaya F, Yilmaz AH, Mammadov R, Cimen FK, Hirik E, Altuner D

  • Korean J Physiol Pharmacol.
  • 2017 Sep;21(5):457-464.
  • doi: 10.4196/kjpp.2017.21.5.457
Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular...

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