Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

16 results
Display

The effects of intra-articular resiniferatoxin on monosodium iodoacetate-induced osteoarthritic pain in rats

Kim Y, Kim EH, Lee KS, Lee K, Park SH, Na SH, Ko C, Kim J, Yooon YW

This study was performed to investigate whether an intra-articular injection of transient receptor potential vanilloid 1 (TRPV1) receptor agonist, resiniferatoxin (RTX) would alleviate behavioral signs of arthritic pain in a...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparison of electrophysiological effects of calcium channel blockers on cardiac repolarization

Lee HA, Hyun SA, Park SG, Kim KS, Kim SJ

Dihydropyridine (DHP) calcium channel blockers (CCBs) have been widely used to treat of several cardiovascular diseases. An excessive shortening of action potential duration (APD) due to the reduction of Ca2+...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Inducibility of human atrial fibrillation in an in silico model reflecting local acetylcholine distribution and concentration

Hwang M, Lee HS, Pak HN, Shim EB

Vagal nerve activity has been known to play a crucial role in the induction and maintenance of atrial fibrillation (AF). However, it is unclear how the distribution and concentration of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Brief low [Mg2+]o-induced Ca2+ spikes inhibit subsequent prolonged exposure-induced excitotoxicity in cultured rat hippocampal neurons

Kim HJ, Yang JS, Yoon SH

Reducing [Mg2+]o to 0.1 mM can evoke repetitive [Ca2+]i spikes and seizure activity, which induces neuronal cell death in a process called excitotoxicity. We examined the issue of whether cultured...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
(E)-3-(3-methoxyphenyl)-1-(2-pyrrolyl)-2-propenone displays suppression of inflammatory responses via inhibition of Src, Syk, and NF-kappaB

Kim Y, Jeong EJ, Han Lee IS, Kim MY, Cho JY

(E)-3-(3-methoxyphenyl)-1-(2-pyrrolyl)-2-propenone (MPP) is an aldol condensation product resulting from pyrrole-2-carbaldehyde and m- and p- substituted acetophenones. However, its biological activity has not yet been evaluated. Since it has been reported...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of D-glucose feeding on mortality induced by sepsis

Kim SS, Sim YB, Park SH, Lee JR, Sharma N, Suh HW

Sepsis is the life-threatening response to infection which can lead to tissue damage, organ failure, and death. In the current study, the effect of orally administered D-glucose on the mortality...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Blockade of Kv1.5 by paroxetine, an antidepressant drug

Lee HM, Hahn SJ, Choi BH

Paroxetine, a selective serotonin reuptake inhibitor (SSRI), has been reported to have an effect on several ion channels including human ether-a-go-go-related gene in a SSRI-independent manner. These results suggest that...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cardamonin inhibits agonist-induced vascular contractility via Rho-kinase and MEK inhibition

Je HD, Jeong JH

The present study was undertaken to investigate the influence of cardamonin on vascular smooth muscle contractility and to determine the mechanism(s) involved. Denuded aortic rings from male rats were used...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Allogeneic clonal mesenchymal stem cell therapy for refractory graft-versus-host disease to standard treatment: a phase I study

Yi HG, Yahng SA, Kim I, Lee JH, Min CK, Kim JH, Kim CS, Song SU

Severe graft-versus-host disease (GVHD) is an often lethal complication of allogeneic hematopoietic stem cell transplantation (HSCT). The safety of clinical-grade mesenchymal stem cells (MSCs) has been validated, but mixed results...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of CoCl2 on multi-lineage differentiation of C3H/10T1/2 mesenchymal stem cells

Yoo HI, Moon YH, Kim MS

Mesenchymal stem cells (MSCs) in the bone marrow and other somatic tissues reside in an environment with relative low oxygen tension. Cobalt chloride (CoCl2) can mimic hypoxic conditions through transcriptional...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-kappaB signaling pathway in mice

Seong KJ, Lee HG, Kook MS, Ko HM, Jung JY, Kim WJ

Adult hippocampal dentate granule neurons are generated from neural stem cells (NSCs) in the mammalian brain, and the fate specification of adult NSCs is precisely controlled by the local niches...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Toxicokinetics of paraquat in Korean patients with acute poisoning

Kim HJ, Kim HK, Lee H, Bae JS, Kown JT, Gil HW, Hong SY

To conduct a kinetic study of paraquat (PQ), we investigated 9 patients with acute PQ intoxication. All of them ingested more than 20 ml of undiluted PQ herbicide to commit...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Activation of K+ channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca2+ ionophore-induced cell death

Yin MZ, Park SW, Kang TW, Kim KS, Yoo HY, Lee J, Hah JH, Sung MH, Kim SJ

Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular Ca2+ ([Ca2+]i)-dependent signaling affects the fate of cancer cells. Here we investigate the role of Ca(2+)-activated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice

Guo Q, Shen Z, Yu H, Lu G, Yu Y, Liu X, Zheng P

Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure. The study aimed to investigate the protective effect of carnosic acid (CA) on APAP-induced acute hepatotoxicity...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria

Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR

Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neural circuit remodeling and structural plasticity in the cortex during chronic pain

Kim W, Kim SK

Damage in the periphery or spinal cord induces maladaptive plastic changes along the somatosensory nervous system from the periphery to the cortex, often leading to chronic pain. Although the role...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr