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11 results

Bisphenol A and 4-tert-Octylphenol Inhibit Cx46 Hemichannel Currents

Oh S

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):73-79.
  • doi: 10.4196/kjpp.2015.19.1.73
Connexins (Cx) are membrane proteins and monomers for forming gap junction (GJ) channels. Cx46 and Cx50 are also known to function as conductive hemichannels. As part of an ongoing effort...
Airway Smooth Muscle Sensitivity to Methacholine in Precision-Cut Lung Slices (PCLS) from Ovalbumin-induced Asthmatic Mice

Kim HJ, Kim Y, Park SJ, Bae B, Kang HR, Cho SH, Yoo HY, Nam JH, Kim WK, Kim SJ

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):65-71.
  • doi: 10.4196/kjpp.2015.19.1.65
Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness (AHR) and reversible airway obstruction. Methacholine (MCh) is widely used in broncho-provocation test to evaluate airway resistance. For experimental investigation,...
Pectin Micro- and Nano-capsules of Retinyl Palmitate as Cosmeceutical Carriers for Stabilized Skin Transport

Ro J, Kim Y, Kim H, Park K, Lee KE, Khadka P, Yun G, Park J, Chang ST, Lee J, Jeong JH, Lee J

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):59-64.
  • doi: 10.4196/kjpp.2015.19.1.59
Retinyl palmitate (RP)-loaded pectinate micro- and nano-particles (PMP and PNP) were designed for stabilization of RP that is widely used as an anti-wrinkle agent in anti-aging cosmeceuticals. PMP/PNP were prepared...
Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium

Son A, Shin DM, Hong JH

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):51-57.
  • doi: 10.4196/kjpp.2015.19.1.51
The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The...
Anti-inflammatory Effects of Flavonoids on TNBS-induced Colitis of Rats

Joo M, Kim HS, Kwon TH, Palikhe A, Zaw TS, Jeong JH, Sohn UD

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):43-50.
  • doi: 10.4196/kjpp.2015.19.1.43
It has been shown that the extracts including eupatilin and quercetin-3-beta-D-glucuronopyranoside had mucoprotective effects on the esophagus and stomach through their antioxidant activities. This study was designed to investigate the...
Isolation and In Vitro Culture of Vascular Endothelial Cells from Mice

Choi S, Kim JA, Kim KC, Suh SH

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):35-42.
  • doi: 10.4196/kjpp.2015.19.1.35
In cardiovascular disorders, understanding of endothelial cell (EC) function is essential to elucidate the disease mechanism. Although the mouse model has many advantages for in vivo and in vitro research,...
ERK Activation by Fucoidan Leads to Inhibition of Melanogenesis in Mel-Ab Cells

Song YS, Balcos MC, Yun HY, Baek KJ, Kwon NS, Kim MK, Kim DS

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):29-34.
  • doi: 10.4196/kjpp.2015.19.1.29
Fucoidan, a fucose-rich sulfated polysaccharide derived from brown seaweed in the class Phaeophyceae, has been widely studied for its possible health benefits. However, the potential of fucoidan as a possible...
Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.

Kim WS, Choi WJ, Lee S, Kim WJ, Lee DC, Sohn UD, Shin HS, Kim W

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):21-27.
  • doi: 10.4196/kjpp.2015.19.1.21
The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of...
Extremely Low Frequency Magnetic Field Modulates the Level of Neurotransmitters

Chung YH, Lee YJ, Lee HS, Chung SJ, Lim CH, Oh KW, Sohn UD, Park ES, Jeong JH

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):15-20.
  • doi: 10.4196/kjpp.2015.19.1.15
This study was aimed to observe that extremely low frequency magnetic field (ELF-MF) may be relevant to changes of major neurotransmitters in rat brain. After the exposure to ELF-MF (60...
Seasonal Acclimatization in Summer versus Winter to Changes in the Sweating Response during Passive Heating in Korean Young Adult Men

Lee JB, Kim TW, Min YK, Yang HM

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):9-14.
  • doi: 10.4196/kjpp.2015.19.1.9
We investigated the sweating response during passive heating (partial submersion up to the umbilical line in 42+/-0.5degrees C water, 30 min) after summer and winter seasonal acclimatization (SA). Testing was...
Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway

Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N

  • Korean J Physiol Pharmacol.
  • 2015 Jan;19(1):1-7.
  • doi: 10.4196/kjpp.2015.19.1.1
Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In...

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