- Dehydroevodiamine.HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats
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Kim HJ, Shin KY, Chang KA, Ahn S, Choi HS, Kim HS, Suh YH
- KMID: 2285491
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):55-59.
- doi: 10.4196/kjpp.2014.18.1.55
Dehydroevodiamine.HCl (DHED) has been reported to prevent memory impairment and neuronal cell loss in a rat model with cognitive disturbance. We investigated the effect of DHED on memory impairment and... -
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- The Pathophysiologic Roles of TRPM7 Channel
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Park HS, Hong C, Kim BJ, So I
- KMID: 2285486
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):15-23.
- doi: 10.4196/kjpp.2014.18.1.15
Transient receptor potential melastatin 7 (TRPM7) is a member of the melastatin-related subfamily and contains a channel and a kinase domain. TRPM7 is known to be associated with cell proliferation,... -
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- Bcl-2 Knockdown Accelerates T Cell Receptor-Triggered Activation-Induced Cell Death in Jurkat T Cells
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Lee YJ, Won TJ, Hyung KE, Lee MJ, Moon YH, Lee IH, Go BS, Hwang KW
- KMID: 2285494
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):73-78.
- doi: 10.4196/kjpp.2014.18.1.73
Cell death and survival are tightly controlled through the highly coordinated activation/inhibition of diverse signal transduction pathways to insure normal development and physiology. Imbalance between cell death and survival often... -
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- Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity
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Xia A, Xue Z, Wang W, Zhang T, Wei T, Sha X, Ding Y, Zhou W
- KMID: 2285493
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):67-72.
- doi: 10.4196/kjpp.2014.18.1.67
To investigate the alteration of c-Jun N-terminal kinase (JNK) activity after myocardial ischemia reperfusion injury (MIRI) and further explore the effect of naloxone postconditioning on MIRI. Forty male Sprague Dawley... -
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- Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility
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Liu FF, Chen DP, Xiong YJ, Lv BC, Lin Y
- KMID: 2285490
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):47-53.
- doi: 10.4196/kjpp.2014.18.1.47
In this study, we propose that diprophylline exerts bidirectional modulation (BM) on the isolated rat jejunal segment depending on its contractile state. The results supported the hypothesis. Diprophylline (20 microM)... -
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- The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-Glucose-Fed Mice
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Sim YB, Park SH, Kim SS, Kim CH, Kim SJ, Lim SM, Jung JS, Ryu OH, Choi MG, Suh HW
- KMID: 2285489
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):41-46.
- doi: 10.4196/kjpp.2014.18.1.41
The possible roles of spinal histamine receptors in the regulation of the blood glucose level were studied in ICR mice. Mice were intrathecally (i.t.) treated with histamine 1 (H1) receptor... -
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- Phosphorylation of Akt Mediates Anti-Inflammatory Activity of 1-p-Coumaroyl beta-D-Glucoside Against Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells
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Vo VA, Lee JW, Kim JY, Park JH, Lee HJ, Kim SS, Kwon YS, Chun W
- KMID: 2285495
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):79-86.
- doi: 10.4196/kjpp.2014.18.1.79
Hydroxycinnamic acids have been reported to possess numerous pharmacological activities such as antioxidant, anti-inflammatory, and anti-tumor properties. However, the biological activity of 1-p-coumaroyl beta-D-glucoside (CG), a glucose ester derivative of... -
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- Anti-Inflammatory and Anti-Superbacterial Properties of Sulforaphane from Shepherd's Purse
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Choi WJ, Kim SK, Park HK, Sohn UD, Kim W
- KMID: 2285488
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):33-39.
- doi: 10.4196/kjpp.2014.18.1.33
Shepherd's purse, Capsella bursa-pastoris (L.) Medik., has been considered a health food for centuries in Asia and is known to contain the isothiocyanate compound sulforaphane. In this study, we evaluated... -
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- Advanced Glycation End Products and Diabetic Complications
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Singh VP, Bali A, Singh N, Jaggi AS
- KMID: 2285485
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):1-14.
- doi: 10.4196/kjpp.2014.18.1.1
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation... -
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- Nitric Oxide-Induced Apoptosis of Human Dental Pulp Cells Is Mediated by the Mitochondria-Dependent Pathway
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Park MY, Jeong YJ, Kang GC, Kim MH, Kim SH, Chung HJ, Jung JY, Kim WJ
- KMID: 2285487
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):25-32.
- doi: 10.4196/kjpp.2014.18.1.25
Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. NO is produced by nitric oxide synthase (NOS), and NOS is abundantly expressed in the human dental... -
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- Reversal of Cisplatin Resistance by Epigallocatechin Gallate Is Mediated by Downregulation of Axl and Tyro 3 Expression in Human Lung Cancer Cells
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Kim KC, Lee C
- KMID: 2285492
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):61-66.
- doi: 10.4196/kjpp.2014.18.1.61
Lung cancer is still the number one cause of death from cancer worldwide. The clinical effect of platinum-based chemotherapy for non-small cell lung cancer is constrained by the resistance to... -
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