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13 results

Corrigendum to: Ursolic Acid-Induced Elevation of Serum Irisin Augments Muscle Strength During Resistance Training in Men

Bang HS, Seo DY, Chung YM, Oh KM, Park JJ, Arturo F, Jeong SH, Kim N, Han J

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):531-531.
  • doi: 10.4196/kjpp.2014.18.6.531
The original version of this article contained misspelled name of author. The name of Figueroa Arturo is replaced with Arturo Figueroa.
TRPV1 in Salivary Gland Epithelial Cells Is Not Involved in Salivary Secretion via Transcellular Pathway

Choi S, Shin YH, Namkoong E, Hwang SM, Cong X, Yu G, Park K

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):525-530.
  • doi: 10.4196/kjpp.2014.18.6.525
Transient receptor potential vanilloid subtype 1 (TRPV1) was originally found in sensory neurons. Recently, it has been reported that TRPV1 is expressed in salivary gland epithelial cells (SGEC). However, the...
Phasic and Tonic Inhibition are Maintained Respectively by CaMKII and PKA in the Rat Visual Cortex

Joo K, Yoon SH, Rhie DJ, Jang HJ

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):517-524.
  • doi: 10.4196/kjpp.2014.18.6.517
Phasic and tonic gamma-aminobutyric acid(A) (GABA(A)) receptor-mediated inhibition critically regulate neuronal information processing. As these two inhibitory modalities have distinctive features in their receptor composition, subcellular localization of receptors, and...
Distinct Cellular Calcium Metabolism in Radiation-sensitive RKO Human Colorectal Cancer Cells

Kim YT, Jo SS, Park YJ, Lee MZ, Suh CK

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):509-516.
  • doi: 10.4196/kjpp.2014.18.6.509
Radiation therapy for variety of human solid tumors utilizes mechanism of cell death after DNA damage caused by radiation. In response to DNA damage, cytochrome c was released from mitochondria...
Transient Receptor Potential C4/5 Like Channel Is Involved in Stretch-Induced Spontaneous Uterine Contraction of Pregnant Rat

Chung S, Kim YH, Joeng JH, Ahn DS

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):503-508.
  • doi: 10.4196/kjpp.2014.18.6.503
Spontaneous myometrial contraction (SMC) in pregnant uterus is greatly related with gestational age and growing in frequency and amplitude toward the end of gestation to initiate labor. But, an accurate...
Scant Extracellular NAD Cleaving Activity of Human Neutrophils is Down-Regulated by fMLP via FPRL1

Hasan MA, Sultan MT, Ahn WG, Kim YJ, Jang JH, Hong CW, Song DK

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):497-502.
  • doi: 10.4196/kjpp.2014.18.6.497
Extracellular nicotinamide adenine dinucleotide (NAD) cleaving activity of a particular cell type determines the rate of the degradation of extracellular NAD with formation of metabolites in the vicinity of the...
Suppression of Peripheral Sympathetic Activity Underlies Protease-Activated Receptor 2-Mediated Hypotension

Kim YH, Ahn DS, Joeng JH, Chung S

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):489-495.
  • doi: 10.4196/kjpp.2014.18.6.489
Protease-activated receptor (PAR)-2 is expressed in endothelial cells and vascular smooth muscle cells. It plays a crucial role in regulating blood pressure via the modulation of peripheral vascular tone. Although...
The Effects of Ischemic Postconditioning on Myocardial Function and Nitric Oxide Metabolites Following Ischemia-Reperfusion in Hyperthyroid Rats

Zaman J, Jeddi S, Ghasemi A

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):481-487.
  • doi: 10.4196/kjpp.2014.18.6.481
Ischemic postconditioning (IPost) could decrease ischemia-reperfusion (IR) injury. It has not yet reported whether IPost is useful when ischemic heart disease is accompanied with co-morbidities like hyperthyroidism. The aim of...
FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1alpha in the Presence of 27-hydroxycholesterol

Heo W, Kim SM, Eo SK, Rhim BY, Kim K

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):475-480.
  • doi: 10.4196/kjpp.2014.18.6.475
We investigated the question of whether cholesterol catabolite can influence expression of inflammatory cytokines via Toll-like receptors (TLR) in monocytic cells. Treatment of THP-1 monocytic cells with 27-hydroxycholesterol (27OHChol) resulted...
Alcohol-induced Hyperlipidemia Is Ameliorated by Orally Administered DWP208, a Sodium Succinate Form of ZYM201

Cho JY, Choi J, Park JG, Yi YS, Hossen MJ, Kim H, Ro J, Cha BC, Yoo ES, Kim JH, Lee J

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):469-474.
  • doi: 10.4196/kjpp.2014.18.6.469
DWP208 is a sodium succinate form of ZYM-201 which is a triterpenoid glycoside isolated from Sanguisorba officinalis, a medicinal plant prescribed for various diseases, such as duodenal ulcers and bleeding...
Streptozotocin Diabetes Attenuates the Effects of Nondepolarizing Neuromuscular Relaxants on Rat Muscles

Huang L, Chen D, Li S

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):461-467.
  • doi: 10.4196/kjpp.2014.18.6.461
The hypothesis of this study was that diabetes-induced desensitization of rat soleus (SOL) and extensor digitorum longus (EDL) to non-depolarizing muscle relaxants (NDMRs) depends on the stage of diabetes and...
Long-term Synaptic Plasticity: Circuit Perturbation and Stabilization

Park JM, Jung SC, Eun SY

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):457-460.
  • doi: 10.4196/kjpp.2014.18.6.457
At central synapses, activity-dependent synaptic plasticity has a crucial role in information processing, storage, learning, and memory under both physiological and pathological conditions. One widely accepted model of learning mechanism...
Role of Cerebrospinal Fluid Biomarkers in Clinical Trials for Alzheimer's Disease Modifying Therapies

Kang JH, Ryoo NY, Shin DW, Trojanowski JQ, Shaw LM

  • Korean J Physiol Pharmacol.
  • 2014 Dec;18(6):447-456.
  • doi: 10.4196/kjpp.2014.18.6.447
Until now, a disease-modifying therapy (DMT) that has an ability to slow or arrest Alzheimer's disease (AD) progression has not been developed, and all clinical trials involving AD patients enrolled...

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