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5 results

Lysophosphatidylcholine Increases Ca2+ Current via Activation of Protein Kinase C in Rabbit Portal Vein Smooth Muscle Cells

Jung S, Lee Y, Han S, Kim Y, Nam T, Ahn D

  • Korean J Physiol Pharmacol.
  • 2008 Feb;12(1):31-35.
  • doi: 10.4196/kjpp.2008.12.1.31
Lysophosphatidylcholine (LPC), a metabolite of membrane phospholipids by phospholipase A(2), has been considered responsible for the development of abnormal vascular reactivity during atherosclerosis. Ca2+ influx was shown to be augmented...
Involvement of Thromboxane A2 in the Modulation of Pacemaker Activity of Interstitial Cells of Cajal of Mouse Intestine

Kim JH, Choi SJ, Yeum CH, Yoon PJ, Choi S, Jun JY

  • Korean J Physiol Pharmacol.
  • 2008 Feb;12(1):25-30.
  • doi: 10.4196/kjpp.2008.12.1.25
Although many studies show that thromboxane A2 (TXA2) has the action of gastrointestinal (GI) motility using GI muscle cells and tissue, there are no reports on the effects of TXA2...
Roles of Dopaminergic D1 and D2 Receptors in Catecholamine Release from the Rat Adrenal Medulla

Baek YJ, Seo YS, Lim DY

  • Korean J Physiol Pharmacol.
  • 2008 Feb;12(1):13-23.
  • doi: 10.4196/kjpp.2008.12.1.13
The aim of the present study was designed to establish comparatively the inhibitory effects of D1-like and D2-like dopaminergic receptor agonists, SKF81297 and R(-)-TNPA on the release of catecholamines (CA)...
Ameliorating Effects of Sulfonylurea Drugs on Insulin Resistance in Otsuka Long-Evans Tokushima Fatty Rats

Park JK, Kim SP, Song DK

  • Korean J Physiol Pharmacol.
  • 2008 Feb;12(1):7-12.
  • doi: 10.4196/kjpp.2008.12.1.7
OLETF (Otsuka Long-Evans Tokushima Fatty) rats are characterized by obesity-related insulin resistance, which is a phenotype of type 2 diabetes. Sulfonylurea drugs or benzoic acid derivatives as inhibitors of the...
Effects of TGF-beta1 Ribbon Antisense on CCl4-induced Liver Fibrosis

Doh KO

  • Korean J Physiol Pharmacol.
  • 2008 Feb;12(1):1-6.
  • doi: 10.4196/kjpp.2008.12.1.1
Ribbon-type antisense oligonucleotide to TGF-beta1(TGF-beta1 RiAS) was designed and tested to prevent or resolve the fibrotic changes induced by CCl4 injection. When Hepa1c1c7 cells were transfected with TGF-beta1 RiAS, the...

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