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5 results

The Role of Janus Kinase in Superoxide-mediated Proliferation of Diabetic Vascular Smooth Muscle Cells

Lee JY, Park JY, Kim CD

  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):31-36.
To elucidate a potential molecular link between diabetes and atherosclerosis, we investigated the role of Janus tyrosine kinase (JAK) for NAD(P)H oxidase-derived superoxide generation in the enhanced proliferative capacity of...
Influence of omega-Conotoxin GVIA, Nifedipine and Cilnidipine on Catecholamine Release in the Rat Adrenal Medulla

Yu BS, Kim BC, Lim DY

  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):21-30.
The present study was designed to establish comparatively the inhibitory effects of cilnidipine (CNP), nifedipine (NIF), and omega-conotoxin GVIA (CTX) on the release of CA evoked by cholinergic stimulation...
Inhibition of Pacemaker Activity of Interstitial Cells of Cajal by Hydrogen Peroxide via Activating ATP-sensitive K(+) Channels

Choi S, Parajuli S, Cheong HS, Paudyal DP, Yeum CH, Yoon PJ, Jun JY

  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):15-20.
To investigate whether hydrogen peroxide (H2O2) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal (ICC) from murine small intestine by using a...
Comparison of Inhibitory Potency of Various Antioxidants on the Activation of BV2 Microglial Cell Lines Induced by LPS

Kong PJ, Park JI, Kwon OY, Han YH, Kim SY, Lee SN, Son HJ, Kim SS

  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):9-13.
Antioxidant properties have been proposed as a mechanism for the putative anti-inflammatory effects of phenolic compounds. To reveal the relationship between antioxidant activity and anti-inflammatory effects of various antioxidants, we...
c-fos mRNA Expression in the Vestibular System following Hypergravity Stimulation in Rats

Jin GS, Lee JH, Lee JH, Lee MY, Kim MS, Jin YZ, Song JH, Park BR

  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):1-7.
Altered environmental gravity, including both hypo- and hypergravity, may result in space adaptation syndrome. To explore the characteristics of this adaptive plasticity, the expression of immediate early gene c-fos mRNA...

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