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10 results

Involvement of Bcl-2 Family and Caspases Cascade in Sodium Fluoride-Induced Apoptosis of Human Gingival Fibroblasts

Jung JY, Park JH, Jeong YJ, Yang KH, Choi NK, Kim SH, Kim WJ

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):289-295.
Sodium fluoride (NaF) has been shown to be cytotoxic and elicit inflammatory response in human. However, the cellular mechanisms underlying NaF-induced cytotoxicity in periodontal tissues have not yet been elucidated....
Increased Rate of Palmitate Oxidation in Adults Female: Comparison with Peri-pubertal Young Female Rats

Lee SY, Kim JY, Kim YW, Park SY

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):283-287.
Although estrogen is known to play a role in fatty acid metabolism, it remains unclear whether fatty acid oxidation in mature female rats differs from fatty acid oxidation in peri-pubertal...
R-(-)-TNPA, a Dopaminergic D2 Receptor Agonist, Inhibits Catecholamine Release from the Rat Adrenal Medulla

Hong SP, Seo HJ, Lim DY

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):273-282.
The aim of the present study was to investigate the effects of R-(-)-2,10,11-trihydroxy-N-propylnoraporphine [R-(-)-TNPA], a selective agonist of dopaminergic D2 receptor and S(-)-raclopride, a selective antagonist of dopaminergic D2 receptor,...
Microarray Analysis of Oxygen-Glucose-Deprivation Induced Gene Expression in Cultured Astrocytes

Joo DH, Han HS, Park JS

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):263-271.
Since astrocytes were shown to play a central role in maintaining neuronal viability both under normal conditions and during stress such as ischemia, studies of the astrocytic response to stress...
Calcium Ions are Involved in Modulation of Melittin-induced Nociception in Rat: I. Effect of Voltage-gated Calcium Channel Antagonist

Shin HK, Le KH

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):255-261.
Melittin-induced nociceptive responses are mediated by selective activation of capsaicin-sensitive primary afferent fibers and are modulated by excitatory amino acid receptor, cyclooxygenase, protein kinase C and serotonin receptor. The present...
Inhibition of Adenosine Triphosphate-stimulated Mucin Secretion from Airway Epithelial Cells by Schizandrin

Heo HJ, Lee HJ, Kim C, Bae KH, Kim YS, Kang SS, Park YC, Kim YH, Seo UK, Seok JH

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):251-254.
Schizandrae Fructus has been used for controlling respiratory allergic or inflammatory diseases in folk medicine and their components, schizandrin, schizandrin-A and gomisin-A were reported to have diverse biological effects. In...
Effect of Genistein, a Tyrosine Kinase Inhibitor, on the Cloned Rat Brain Potassium Channel Kv1.5

Choi BH

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):243-249.
The effect of genistein, widely used as a specific tyrosine kinase inhibitor, on rat brain Kv1.5 channels which were stably expressed in Chinese hamster ovary cells was investigated using the...
Effects of Ethosuximide on the Pilocarpine Induced Seizure in Rat Model of Neuronal Migration Disorder

Kim BK, Choi IS, Cho JH, Jang IS, Lee MG, Choi BJ

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):235-242.
Cortical malformation-associated epileptic seizures are resistant to conventional anticonvulsant drugs. Relatively little research has been conducted on the effects of antiepileptic drugs (AEDs) on seizure activity in a rat model...
Sweating by Exercise Controls Body Temperature through Increase of Interleukin-1beta

Bae JS, Shin YO, Lee JB, Seok H, Min YK, Yang HM

  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):231-234.
This study was designed to investigate the expression and production of interleukin-1beta (IL-1beta) in human peripheral blood of trained runners and untrained controls after temporary moderate intensity exercise. Male long-distance...
Neurovascular Mechanisms in Stroke, Neurodegeneration and Recovery


  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):223-229.
The emerging concept of the neurovascular unit may enable a powerful paradigm shift for neuroscience. Instead of a pure focus on the "neurobiology" of disease, an opportunity now exists to...

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