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NADPH Oxidase and Mitochondrial ROS are Involved in the TNF-alpha-induced Vascular Cell Adhesion Molecule-1 and Monocyte Adhesion in Cultured Endothelial Cells

Yu JH, Kim CS, Yoo DG, Song YJ, Joo HK, Kang G, Jo JY, Park JB, Jeon BH

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):217-222.
Atherosclerosis is considered as a chronic inflammatory process. However, the nature of the oxidant signaling that regulates monocyte adhesion and its underlying mechanism is poorly understood. We investigated the role...
Blunted Indomethacin-Induced Downregulation of Aquaporins by Nitric Oxide Synthesis Inhibition in Rats

You JH, Lee S, Bae EH, Ma SK, Kim SW, Lee JU

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):213-216.
The present study was aimed to determine whether nitric oxide (NO) plays a role in the regulation of aquaporin (AQP) channels in the kidney. Male Brattleboro rats (250~300 g body...
Monoamine Oxidase Inhibitors Attenuate Cytotoxicity of 1-Methyl-4-phenylpyridinium by Suppressing Mitochondrial Permeability Transition

Lee CS

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):207-212.
Mitochondrial permeability transition has been shown to be involved in neuronal cell death. Mitochondrial monoamine oxidase (MAO)-B is considered to play a part in the progress of nigrostriatal cell death....
Involvement of ERK1/2 and JNK Pathways in 17beta-estradiol Induced Kir6.2 and SK2 Upregulation in Rat Osteoblast-like Cells

Kim JW, Yang EK

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):199-205.
The functional expression of potassium (K+) channels has electrophysiologically been studied in bone cells from several species, however, their identity and regulation of gene expressions in bone cells are not...
Methylene Blue-stained Interstitial Cells are Electrically Active in the Myenteric Board Freshly Prepared from the Murine Small Intestine

Lee KP, Jeon JH, So I, Kim KW

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):193-198.
Many gastrointestinal muscles show electrical oscillation, so-called "slow wave", originated from interstitial cells of Cajal (ICCs). Thus, a technique to freshly isolate the cells is indispensable to explore the electrophysiological...
Changes of Serum Ferritin in Acute Lung Injury Induced by Intestinal Ischemia/Reperfusion

Park SD, Park YY

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):187-191.
Serum ferritin levels are increased in subjects at-risk for or with acute lung injury (ALI), and there are observations to suggest that increases in serum ferritin levels may help predict...
Effect of Rosiglitazone on Myocardial Ischemia-Reperfusion Injury in Rat Heart

Ha KC

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):181-186.
This study was undertaken to evaluate whether peroxisome proliferator-activated-receptor-gamma (PPAR-gamma) agonist-rosiglitazone (ROSI) induces postischemic functional recovery in Langendorf heart model. Hearts isolated from normal rats were subjected to 20 min...
Gene Expression Profile in Microglia following Ischemia-Reperfusion Injury

Oh JH, Han HS, Park JS

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):173-180.
Microglial activation is thought to play a role in the pathogenesis of many brain disorders. Therefore, understanding the response of microglia to noxious stimuli may provide insights into their role...
A Simple Method for Predicting Hippocampal Neurodegeneration in a Mouse Model of Transient Global Forebrain Ischemia

Cho KO, Kim SK, Cho YJ, Sung KW, Kim SY

  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):167-172.
In the present study, we developed a simple method to predict the neuronal cell death in the mouse hippocampus and striatum following transient global forebrain ischemia by evaluating both cerebral...

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