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N-methyl-D-aspartate (NMDA) and Non-NMDA Receptors are Involved in the Production and Maintenance of Nociceptive Responses by Intraplantar Injection of Bee Venom and Melittin in the Rat

Kim JH, Shin HK

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):179-186.
Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal...
What is the Key Step in Muscle Fatty Acid Oxidation after Change of Plasma Free Fatty Acids Level in Rats?

Doh KO, Suh SD, Kim JY

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):173-177.
The purpose of this study was to discern the critical point in skeletal muscle fatty acid oxidation by changing plasma free fatty acids (FFA) level in rat. In the study,...
Expression of Nitric Oxide Synthase and Endothelin-1 in Human Uterine Artery from Full-Term Pregnancies

Choi OH, Lee SH, Kim EJ, Kim KH, Rhim BY

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):165-172.
The aim of this study was to determine the roles of ET-1 and NO on uterine blood flow in pregnancy. Uterine arteries were isolated from 17 nonpregnant and 12 pregnant...
Protective Effect of N-Acetylcysteine on Progression of Adriamycin-induced Nephropathy

Han SW, Kim HJ, Paik SS, Lee JU

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):159-164.
Effects of antioxidants on the established nephropathy were investigated. The experimental nephropathy was induced in rats by intravenous injection of adriamycin (2 mg/kg). Six weeks later, when proteinuria was apparent,...
Effects of Sphingosine-1-phosphate, Furosemide and Indomethacin on Mucin Release from Airway Goblet Cells

Kim JO, Kim HS, Kim SY, Jeong SS, Heo HJ, Seok JH, Lee CJ

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):155-158.
In this study, we investigated whether sphingosine-1-phosphate, furosemide, and indomethacin affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for...
Preventive Effect of Serotonergic Drugs on LPS-Induced Acute Anorexia in Rats

Park SY, Kim KH, Ahn DK, Park TI, Kim JY, Kim YW, Lee DC, Lee SK

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):149-153.
The aim of the present study was to determine whether serotonergic drugs could reverse lipopolysaccharide (LPS) -induced anorexia in rats. LPS (500microgram/kg body weight) and all serotonergic drugs, except for...
Peripheral Nerve Injury Alters Excitatory and Inhibitory Synaptic Transmission in Rat Spinal Cord Substantia Gelatinosa

Youn DH

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):143-147.
Following peripheral nerve injury, excessive nociceptive inputs result in diverse physiological alterations in the spinal cord substantia gelatinosa (SG), lamina II of the dorsal horn. Here, I report the alterations...
Effects of a delta-opioid Agonist on the Brainstem Vestibular Nuclear Neuronal Activity of Rats

Kim TS, Huang M, Jang MJ, Jeong HS, Park JS

  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):137-141.
This study was undertaken to investigate the effects of [D-Ala2, D-Leu5]-enkephalin (DADLE) on the spontaneous activity of medial vestibular nuclear neurons of the rat. Sprague-Dawley rats, aged 14 to 16...

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