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Calcium Ion Dynamics after Dexamethasone Treatment in Organotypic Cultured Hippocampal Slice

Chae HJ, Kang TH, Park JH

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):363-369.
It is imperative to analyse brain injuries directly in real time, so as to find effective therapeutic compounds to protect brain injuries by stress. We established a system which could...
Direct Block of Cloned K+ Channels, Kv1.5 and Kv1.3, by Cyclosporin A, Independent of Calcineurin Inhibition

Choi BH, Hahn SJ

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):353-361.
The interaction of cyclosporine A (CsA), an immunosuppressant, with rat brain Kv1.5 (Kv1.5) channels, which were stably expressed in Chinese hamster ovary cells, was investigated using the whole-cell patch-clamp technique....
Effects of Nitric Oxide on Inhibitory Receptors of Rod Bipolar Cells of Rat Retina

Park NG, Bai SH, Jung CS, Chun MH

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):347-352.
The effects of nitric oxide (NO) on inhibitory neurotransmitter receptors and some types of inhibitory receptors in dissociated rod bipolar cell (RBC) were investigated. In the whole cell voltage-clamping mode,...
The Effects of DTBNP on Intracellular Ca2+ Signaling in Cultured Bovine Aortic Endothelial Cells

Park SJ, Kim BJ, Zhu MH, So I, Kim KW

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):341-346.
The mechanism underlying oxidant-induced intracellular Ca2+ ([Ca2+]i) increase was studied in cultured bovine aortic endothelial cells (BAECs) using fura-2 AM. In the presence of 2 mM extracellular Ca2+, the application...
PKA-Mediated Regulation of B/K Gene Transcription in PC12 Cells

Choi MH, Kim HS, Choi SH, Kim MY, Jang YS, Jang YM, Lee JH, Jeong SW, Kim IK, Kwon OJ

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):333-339.
B/K protein is a novel protein containing double C2-like domains. We examined the specific signaling pathway that regulates the transcription of B/K in PC12 cells. When the cells were treated...
Gene Transfer of Cu/ZnSOD to Cerebral Vessels Prevents Subarachnoid Hemorrhage-induced Cerebral Vasospasm

Yun MR, Kim DE, Heo HJ, Park JY, Lee JY, Bae SS, Kim CD

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):327-332.
The preventive effects of gene transfer of human copper/zinc superoxide dismutase (Cu/ZnSOD) on the development of cerebral vasospasm after subarachnoid hemorrhage (SAH) were examined using a rat model of SAH....
Effects of Ambroxol, S-carboxymethylcysteine, Dextromethorphan and Noscapine on Mucin Release from Airway Goblet Cells

Heo HJ, Lee HJ, Yoon CS, Lim SP, Seok JH, Seo UK, Lee CJ

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):323-326.
In the present study, we investigated whether ambroxol, S-carboxymethyl-L-cysteine, dextromethorphan and noscapine affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and...
Conditioned Medium from Dying Smooth Muscle Cell Induced Apoptotic Death

Bu MH, Lee KA, Kim KH, Rhim BY

  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):315-322.
In this study, the authors investigated whether death of vascular smooth muscle cell (VSMC) had a pathological pertinence. Conditioned media obtained from rat aorta smooth muscle cell (SMC) that were...

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