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Helicobacter pylori Vacuolating Toxin Exhibits Polar Activity of Cl Secretion and Secretory Response to Carbachol in T84 Cells

Jin NG, Jin YR, So I, Kim KW

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):289-293.
To investigate whether VacA (vacuolating toxin) produced by Helicobacter pylori Korean stain 99 induces intestinal secretion, purified VacA was added to T84 cell monolayers mounted in Ussing chambers, and electrical...
Comparative Study on the Nociceptive Responses Induced by Whole Bee Venom and Melittin

Shin HK, Lee KH, Lee SE

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):281-288.
The present study was undertaken to confirm whether melittin, a major constituent of whole bee venom (WBV), had the ability to produce the same nociceptive responses as those induced by...
Inhibition of Inducible Nitric Oxide Synthase Expression by YS 49, a Synthetic Isoquinoline Alkaloid, in ROS 17/2.8 Cells Activated with TNF-alpha, IFN-gamma and LPS

Kang YJ, Kang SY, Lee YS, Park MK, Kim HJ, Seo HG, Lee JH, Yun-Choi H, Chang KC

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):273-280.
Nitric oxide (NO) has been suggested to act as a mediator of cytokine-induced effects of turn over of bone. Activation of the inducible nitric oxide synthase (iNOS) by inflammation has...
Influence of Cilnidipine on Catecholamine Release in the Perfused Rat Adrenal Medulla

Woo SC, Baek YJ, Lim DY

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):265-272.
The present study was attempted to investigate the effect of cilnidipine (FRC-8635), which is a newly synthesized novel dihydropyridine (DHP) type of organic Ca2 channel blockers, on secretion of catecholamines...
Vibrio vulnificus Cytolysin Forms Anion-selective Pores on the CPAE Cells, a Pulmonary Endothelial Cell Line

Choi BH, Park BH, Kwak YG

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):259-264.
Cytolysin produced by Vibrio vulnificus has been incriminated as one of the important virulence determinants in V. vulnificus infection. Ion selectivity of cytolysin-induced pores was examined in a CPAE cell,...
Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration

Lee H, Park C, Choi SY, Oh SB, Park K, Kim JS, Lee SJ

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):253-257.
Schwann cells play an important role in peripheral nerve regeneration. Upon neuronal injury, activated Schwann cells clean up the myelin debris by phagocytosis, and promote neuronal survival and axon outgrowth...
Effects of Fetal Mesencephalic Cell Grafts on the Intrastriatal 6-hydroxydoapmine Lesioned Rats

Joo WS, Nam E, Im HI, Jung JA, Lee ES, Hwang YJ, Kim YS

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):245-251.
The effects of fetal mesencephalic cell grafts on the restoration of nigrostriatal dopaminergic function were studied in the intrastriatal 6-hydroxydopamine-lesioned rats. Four weeks after lesioning, transplantation of ventral mesencephalic cells...
Effect of Minocycline on Activation of Glia and Nuclear Factor kappa B in an Animal Nerve Injury Model

Gu EY, Han HS, Park JS

  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):237-243.
Glial cells are activated in neuropathy and play a key role in hyperalgesia and allodynia. This study was performed to determine whether minocycline could attenuate heat hyperalgesia and mechanical allodynia,...

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