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Cytotoxicological Effect of Tebufenozide, an Insect Growth Regulator (IGR) : Stimulation of Filamentous Actin Reorganization and Enhancement of Hsp27 Expression in Drosophila Kc Cells

Hwang JN, Jung HJ, Seo YR

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):351-354.
The cytotoxicological responses to insect growth regulator (IGR), using tebufenozide as ecdysteroid mimic, were investigated in Drosophila Kc cells. Treatment of Kc cells with tebufenozide showed significant growth inhibition and...
Hyperthermia-induced Apoptosis is Independent upon DNA Strand Breaks in Human Lymphoid Cells

Jung HJ, Ka WH, Hwang JN, Seo YR

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):345-349.
Heat shock (43oC for 60 minutes) is sufficient to induce apoptosis in a wide number of cell lines. In this study, we asked whether DNA strand breaks are responsible for...
MAPK Activation and Cell Viability after H2O2 Stimulation in Cultured Feline Ileal Smooth Muscle Cells

Song HJ, Jeong JH, Lee DK, Lee TS, Min YS, Sohn UD

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):339-344.
Recent data have shown the importance of oxidative stresses in the pathogenesis of inflammatory bowel disease, crohn's disease and ulcerative colitis. H2O2, reactive oxygen species (ROS) donor, has been reported...
Ca2 -activated K Currents of Pancreatic Duct Cells in Guinea-pig

Lee HW, Li J, Koo NY, Piao ZG, Hwang SM, Han JW, Choi HS, Lee JH, Kim JS, Park K

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):335-338.
There are numerous studies on transepithelial transports in duct cells including Cl and/or HCO3. However, studies on transepithelial K transport of normal duct cells in exocrine glands are scarce. In...
Effects of Proinflammatory Cytokines and Natural Products on Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells

Park JS, Kim HS, Seok JH, Hur GM, Park JS, Seo UK, Lee CJ

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):329-333.
In this study, we investigated whether TNF-alpha, IL-1beta, CTMA (carboxymethyl trimethylammonium) and LPD (Lup-20[29]-ene-3beta, 28-diol) affect mucin release from airway goblet cells and compared the activities of these agents with...
Effect of Defibrotide on Rat Reflux Esophagitis

Kim HK, Choi SR, Choi SJ, Chio MS, Shin YK

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):319-327.
This study was aimed at evaluating the effect of defibrotide on the development of the surgically induced reflux esophagitis, on gastric secretion, lipid peroxidation, polymorphonuclear leukocytes (PMNs) accumulation, polymorphonuclear leukocytes...
Mechanism of Acetylcholine-induced Endothelium-dependent Relaxation in the Rabbit Carotid Artery by M3-receptor Activation

Song YJ, Kwon SC

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):313-317.
The present study were designed to characterize the action mechanisms of acetylcholine (ACh) -induced endothelium-dependent relaxation in arteries precontracted with high K (70 mM). For this, we simultaneously measured both...
The Improvement of Learning and Memory Ability of Normal Persons by BF-7

Lee SH, Kim YS, Kang YK, Kwon OS, Shin YK, Song JH, Lee MY, Lee KG, Yeo JH, Lee WB, Lee TJ, Kim SS

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):307-312.
To investigate whether BF-7, extracted from Bombyx mori, improved learning and memory of ordinary people, Rey-Kim Memory Test was performed with placebo group (32 persons), 200 mg BF-7 treated group...
Effects of NMDA, AMPA and Kainate on the Release of Acetylcholine in Rat Hippocampal and Striatal Slices

Kim DK, Lee S, Jung KY, Kim JK, Choi BK

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):301-305.
This study examined the effects of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate on basal and electrically-evoked release of acetylcholine (ACh) from the rat hippocampal and striatal slices which...
Effect of Fluoxetine on the Induction of Long-term Potentiation in Rat Frontal Cortex

Kim HS, Kim HS, Hahn SJ, Kim MJ, Yoon SH, Jo YH, Kim MS, Rhie DJ

  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):295-300.
Serotonin (5-hydroxytroptamine, 5-HT) has been shown to affect the induction of long-term potentiation (LTP) in the cortex such as the hippocampus, the visual cortex and the prefrontal cortex. Fluoxetine, as...

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