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7 results

Multiple Regulation of Roundabout (Robo) Phosphorylation in a Heterologous Cell System

Park HT

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):111-115.
Roundabout (Robo) is the transmembrane receptor for slit, the neuronal guidance molecule. In this study, the tyrosine phosphorylation of Robo was observed in Robo-transfected human embryonic kidney cells and developing...
Heterogeneity of the SR-dependent Inward Na+-Ca2+ Exchange Current in the Heavily Ca2+-buffered Rat Ventricular Myocytes

Yoon KB, Ahn SW, Ko CM

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):101-110.
Voltage-sensitive release mechanism was pharmacologically dissected from the Ca2+-induced Ca2+ release in the SR Ca2+ release in the rat ventricular myocytes patch-clamped in a whole-cell mode. SR Ca2+ release process...
Nitric Oxide-cGMP-Protein Kinase G Pathway Contributes to Cardioprotective Effects of ATP-Sensitive K+ Channels in Rat Hearts

Cuong DV, Kim N, Cho HC, Kim E, Han J

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):95-100.
Ischemic preconditioning (IPC) has been accepted as a heart protection phenomenon against ischemia and reperfusion (I/R) injury. The activation of ATP-sensitive potassium (KATP) channels and the release of myocardial nitric...
Effects of Central Interleukin-1 on the Cardiovascular Response in Hemorrhaged Rats

Kang JH, Jang JH, Ahn DK, Park JS

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):89-94.
The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a...
Effects of Chlorhexidine digluconate on Rotational Rate of n- (9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes

Jang HO, Kim DW, Kim BI, Sim HG, Lee YH, Lee JH, Bae JH, Bae MK, Kwon TH, Yun I

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):83-88.
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids...
Increase of Synapsin I, Phosphosynapsin (ser-9), and GAP-43 in the Rat Hippocampus after Middle Cerebral Artery Occlusion

Jung YJ, Huh PW, Park SJ, Park JS, Lee KE

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):77-81.
The loss of neurons and synaptic contacts following cerebral ischemia may lead to a synaptic plastic modification, which may contribute to the functional recovery after a brain lesion. Using synapsin...
Presynaptic Mechanism Underlying Regulation of Transmitter Release by G Protein Coupled Receptors

Takahashi , Kajikawa Y, Kimura M, Saitoh N, Tsujimoto

  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):69-76.
A variety of G protein coupled receptors (GPCRs) are expressed in the presynaptic terminals of central and peripheral synapses and play regulatory roles in transmitter release. The patch-clamp whole-cell recording...

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