- Overexpressed Mitochondrial Thioredoxin Protects PC12 Cells from Hydrogen Peroxide and Serum-deprivation
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Lee YS, Yu SA
- KMID: 1607352
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):33-37.
Oxidative damage to mitochondria is a critical mechanism in necrotic or apoptotic cell death induced by many kinds of toxic chemicals. Thioredoxin (Trx) family proteins are known to play protective... -
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- Acute Effect of Alcohol and Nicotine on 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal and Median Raphe of Rats
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Jang MH, Shin MC, Chang HK, Lee TH, Kim KH, Kim YJ, Kim CJ
- KMID: 1607347
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):5-8.
Alcohol abuse and cigarette smoking have been on the rise worldwide and it has been reported that alcohol and nicotine influence serotonergic neuronal activity in the dorsal raphe. Serotonin (5-hydroxytryptamine,... -
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- 4-Aminopyridine Inhibits the Large-conductance Ca2+ -activated K+ Channel (BKCa) Currents in Rabbit Pulmonary Arterial Smooth Muscle Cells
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Bae YM, Kim A, Kim B, Cho SI, Kim J, Earm YE
- KMID: 1607350
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):25-28.
Ion channel inhibitors are widely used for pharmacological discrimination between the different channel types as well as for determination of their functional role. In the present study, we tested the... -
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- Regulation of [3H]Norepinephrine Release by Opioids in Human Cerebral Cortex
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Woo RS, Shin BS, Kim CJ, Shin MS, Jeong MS, Zhao RJ, Kim KW
- KMID: 1607346
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):1-3.
To investigate the receptors mediating the regulation of norepinephrine (NE) release in human cerebral cortex slices, we examined the effects of opioid agonists for mu-, delta-, and kappa -receptors on... -
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- Inhibition of DNA-dependent Protein Kinase by Blocking Interaction between Ku Complex and Catalytic Subunit of DNA-dependent Protein Kinase
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Kim CH, Cuong DV, Kim JS, Kim N, Kim E, Han J
- KMID: 1607348
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):9-14.
Recent studies indicated that cancer cells become resistant to ionizing radiation (IR) and chemotherapy drugs by enhanced DNA repair of the lesions. Therefore, it is expected to increase the killing... -
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- Effects of Noradrenaline on the Membrane Potential of Prostatic Neuroendocrine Cells of Rat
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Kim JH, Shin SY, Uhm DY, Kim SJ
- KMID: 1607354
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):47-52.
The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both alpha 1- and alpha... -
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- Apo-1/Fas (CD95) Gene Polymorphism in Korean Hepatocellular Carcinoma Patients
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Kim SS, Hong SJ, Ahn YG, Kim BS, Yuh YJ, Han KY, Lee HJ, Chung JH, Yim SV, Cho J, Park YH
- KMID: 1607351
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):29-31.
It is well known that different expression of Apo-1/Fas (CD95) plays important roles in various tumors and hepatocellular carcinoma (HCC) pathogenesis. Apo-1/Fas mediated apoptosis is one of the important pathways... -
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- Dietary Ascorbate Supplementation Reduces Oxidative Tissue Damage and Expression of iNOS in the Kidney of Streptozotocin Induced Diabetic Rats
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Choi MS, Jang YY, Lee WS, Song JH, Shin YK
- KMID: 1607353
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):39-45.
Reactive oxygen species (ROS) have been suggested to be contributory factors in complications of diabetes mellitus. In the present study, we investigated the generation of superoxide, the lipid peroxide level... -
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- Thiol-dependent Redox Mechanisms in the Modification of ATP-Sensitive Potassium Channels in Rabbit Ventricular Myocytes
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Han J, Kim N, Cuong DV, Kim C, Kim E
- KMID: 1607349
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):15-23.
Cellular redox state is known to be perturbed during ischemia and that Ca2+ and K+ channels have been shown to have functional thiol groups. In this study, the properties of... -
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