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7 results

Phytoestrogen-Induced Phosphorylation of MAP Kinase in Osteoblasts is Mediated by Membrane Estrogen Receptor

Park YH, Park HK, Lee HJ, Park SM, Choi SW, Lee WJ

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):165-170.
We have previously demonstrated that phytoestrogens isolated from safflower seeds significantly attenuated bone loss in ovariectomized rats, and directly stimulated proliferation and differentiation of cultured osteoblastic cells. In an attempt...
Assessment of an Apo-1/Fas Promoter Polymorphism in Korean Schizophrenia Patients

Kim SA, Kim YJ, Choe BK, Lee HJ, Kim JW, Park JD, Kim CJ, Park SJ, Jung JC, Chung JH

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):161-164.
Apoptosis has been hypothesized to be involved in the pathogenesis in schizophrenia. A large number of genes are known to mediate the apoptotic process; Apo-1/Fas (CD95) is a well-known example...
A Role of Mitogen Activated Protein Kinases and Inflammatory Responses in Gender Differences in Kidney Ischemia Injury

Park KM, Han HJ

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):155-160.
It is not known whether gender differences play a role in susceptibility to ischemic acute renal failure. Thus, we examined if there were any differences in susceptibility between male and...
Effects of Central GABA and Glutamate on Blood Pressure and Single Unit Spikes in the RVLM of Rats

Park JS, Lee ZI, Jang JH, Ahn DK

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):149-154.
The blood pressure (BP) is regulated by the nervous system and humoral factors, such as renin- angiotensin system, vasopressin and others. In the present study, we examined the central effects...
Calcium Influx is Responsible for Afterdepolarizations in Rat Hippocampal Dentate Granule Cells

Park WS, Lee SH

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):143-148.
Granule cells in dentate gyrus of hippocampus relay information from entorhinal cortex via perforant fiber to pyramidal cells in CA3 region. Their electrical activities are known to be closely associated...
Analysis of a Sphingosine 1-phosphate Receptor hS1P3 in Rat Hepatoma Cells


  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):139-142.
To examine intracellular signaling of human S1P3 (hS1P3), a sphingosine 1-phosphate (S1P) receptor in plasma membrane, hS1P3 DNA was transfected into RH7777 rat hepatoma cell line, and the inhibition of...
Molecular Mechanism of Pancreatic Bicarbonate Secretion

Lee MG, Kim JW, Kim KH, Muallem S

  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):131-138.
Thanks to recent progress in availability of molecular and functional techniques it became possible to search for the basic molecular and cellular processes that mediate and control HCO3- and fluid...

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