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9 results

Comparisons of Renoprotective Activities between White Ginseng Radix and Rootlet in Spontaneously Hypertensive Rats with Diabetes

Chung SH, Ko SK, Park SH

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):57-61.
The renoprotective activities of white ginseng radix and rootlet were compared in spontaneously hypertensive rat (SHR) with diabetes. During oral administration of white ginseng radix (Ginseng Radix Alba, GRA) and...
Inwardly Rectifying K+ Currents in Gastric Myocytes of Guinea-pig

Jun JY, Yeum CH, Yoon PJ, Jang IY, Cho NS, Cho SH, Kong ID, Kim TW, So I, Kim KW

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):47-56.
To identify the presence of inwardly rectifying K+ channels and its characteristics, membrane currents were measured using a whole-cell patch clamp from isolated gastric myocytes of guinea-pig. Change of external...
Renal Tubular Acidosis in Cadmium-Intoxicated Rats

Ahn DW, Kim KR, Choi JK, Park YS

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):41-46.
Effect of cadmium (Cd) intoxication on renal acid-base regulation was studied in adult male Sprague-Dawley rats. Cd intoxication was induced by subcutaneous injections of CdCl2 at a dose of 2...
Ca2+ Sensitization Mechanism in Stretch-induced Myogenic Tone

Kim JS, Ryu SK, Ahn DS, Kang BS, Lee YH

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):33-40.
It has been suggested that Ca2+ sensitization mechanisms might contribute to myogenic tone, however, specific mechanisms have not yet been fully identified. Therefore, we investigated the role of protein kinase...
Effects of gamma-Aminobutyric Acid on Pancreatic Amylase Secretion Evoked by Sodium Oleate in Anesthetized Rats

Park YD, Cui ZY, Park HS, Park HJ

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):27-32.
gamma-Aminobutyric Acid (GABA) is contained in pancreatic islet beta-cells although its physiological role in pancreatic exocrine function is completely unknown at the present time. Recently, we have reported that exogenous...
Transport of Tetraethylammonium in Renal Cortical Endosomes of Cadmium-Intoxicated Rats

Park HS, Kim KR, Park YS

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):21-26.
Effects of cadmium (Cd) intoxication on renal endosomal accumulation of organic cations (OC ) were studied in rats using 14C-tetraethylammnium (TEA) as a substrate. Cd intoxication was induced by s.c....
Involvement of Vascular NAD(P)H Oxidase-derived Superoxide in Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats

Kim DE, Kim CD

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):15-20.
The role of vascular NAD(P)H oxidase in subarachnoid hemorrhage (SAH)-induced vasospasm in the basilar artery was examined in a rat model. Arterial vasospasm characterized by increased wall thickness and decreased...
Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis

Sung KW, Kim SY, Kim ON, Lee SB

  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior...
Congenital LQT Syndromes: From Gene to Torsade de Pointes


  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):1-8.
Congenital Long QT syndrome (LQTs) is a relatively rare pathologic disorder but results frequently in sudden cardiac death. Of the six LQTs that have been clinically described, five have been...

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