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Congenital LQT Syndromes: From Gene to Torsade de Pointes

Carmeliet

  • KMID: 1614851
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):1-8.
Congenital Long QT syndrome (LQTs) is a relatively rare pathologic disorder but results frequently in sudden cardiac death. Of the six LQTs that have been clinically described, five have been...
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Inwardly Rectifying K+ Currents in Gastric Myocytes of Guinea-pig

Jun JY, Yeum CH, Yoon PJ, Jang IY, Cho NS, Cho SH, Kong ID, Kim TW, So I, Kim KW

  • KMID: 1614860
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):47-56.
To identify the presence of inwardly rectifying K+ channels and its characteristics, membrane currents were measured using a whole-cell patch clamp from isolated gastric myocytes of guinea-pig. Change of external...
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Renal Tubular Acidosis in Cadmium-Intoxicated Rats

Ahn DW, Kim KR, Choi JK, Park YS

  • KMID: 1614859
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):41-46.
Effect of cadmium (Cd) intoxication on renal acid-base regulation was studied in adult male Sprague-Dawley rats. Cd intoxication was induced by subcutaneous injections of CdCl2 at a dose of 2...
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Involvement of Vascular NAD(P)H Oxidase-derived Superoxide in Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats

Kim DE, Kim CD

  • KMID: 1614853
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):15-20.
The role of vascular NAD(P)H oxidase in subarachnoid hemorrhage (SAH)-induced vasospasm in the basilar artery was examined in a rat model. Arterial vasospasm characterized by increased wall thickness and decreased...
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Transport of Tetraethylammonium in Renal Cortical Endosomes of Cadmium-Intoxicated Rats

Park HS, Kim KR, Park YS

  • KMID: 1614854
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):21-26.
Effects of cadmium (Cd) intoxication on renal endosomal accumulation of organic cations (OC ) were studied in rats using 14C-tetraethylammnium (TEA) as a substrate. Cd intoxication was induced by s.c....
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Effects of gamma-Aminobutyric Acid on Pancreatic Amylase Secretion Evoked by Sodium Oleate in Anesthetized Rats

Park YD, Cui ZY, Park HS, Park HJ

  • KMID: 1614855
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):27-32.
gamma-Aminobutyric Acid (GABA) is contained in pancreatic islet beta-cells although its physiological role in pancreatic exocrine function is completely unknown at the present time. Recently, we have reported that exogenous...
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Ca2+ Sensitization Mechanism in Stretch-induced Myogenic Tone

Kim JS, Ryu SK, Ahn DS, Kang BS, Lee YH

  • KMID: 1614857
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):33-40.
It has been suggested that Ca2+ sensitization mechanisms might contribute to myogenic tone, however, specific mechanisms have not yet been fully identified. Therefore, we investigated the role of protein kinase...
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Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis

Sung KW, Kim SY, Kim ON, Lee SB

  • KMID: 1614852
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior...
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Comparisons of Renoprotective Activities between White Ginseng Radix and Rootlet in Spontaneously Hypertensive Rats with Diabetes

Chung SH, Ko SK, Park SH

  • KMID: 1614861
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):57-61.
The renoprotective activities of white ginseng radix and rootlet were compared in spontaneously hypertensive rat (SHR) with diabetes. During oral administration of white ginseng radix (Ginseng Radix Alba, GRA) and...
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