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Effect of ethanol on Na+-Pi uptake in opossum kidney cells: Role of membrane fluidization and reactive oxygen species

Park IH, Hwang MY, Woo JS, Jung JS, Kim YK

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):529-538.
This study was undertaken to examine the effect of ethanol on Na+-dependent phosphate (Na+-Pi) uptake in opossum kidney (OK) cells, an established renal proximal tubular cell line. Ethanol inhibited Na+-dependent component of phosphate...
Lipid peroxidation, NF-kappaB activation and cytokine production in neutrophil-stimulated pancreatic acinar cells

Kim H, Seo JY, Cho SH, Kim KH

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):521-528.
Reactive oxygen species (ROS), generated by infiltrating neutrophils, are considered as an important regulator in the pathogenesis and deveolpment of pancreatitis. The present study aims to investigate whether neutrophils primed by 4 beta-phorbol...
Changes in phosphate transporter activity evaluated by phosphonoformic acid binding in cadmium-exposed renal brush-border membranes

Chung JM, Ahn DW, Kim KR, Park YS

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):513-519.
Direct exposure of renal tubular brush-border membranes (BBM) to free cadmium (Cd) causes a reduction in phosphate (Pi) transport capacity. Biochemical mechanism of this reduction was investigated in the present study. Renal proximal...
Effect of prostaglandins D2, E2 and I2 on the regulation of KATP channel activity in rat cardiac myocytes

Ju JM, Nah SY, Kim JH

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):507-512.
Contribution of prostaglandins D2, E2 and I2 (PGD2, PGE2 and PGI2) on the regulation of ATP-sensitive K+ channel (KATP channel) was investigated in isolated single rat ventricular cardiac myocytes using the patch clamp...
Two dinucleotide repeat polymorphisms (AC/TG and GT/CA) in the 5' upstream region of the mouse tryptophan hydroxylase gene

Yim SV, Chi SG, Chung SH, Lee HJ, Kim MJ, Park SJ, Jung JC, Chung JH

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):501-505.
Tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin biosynthesis, is primarily expressed in serotonergic neurons of the raphe nuclei. Simple tandem repeat polymorphisms, typically one to four nucleotides long, are tandemly repeated several...
Electroencephalographic correlation dimension changes with depth of halothane

Lee MG, Park EJ, Choi JM, Yoon MH

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):491-499.
This study was designed to evaluate the efficacy of dynamic parameters, such as correlation dimension D2, by comparing spectral electroencephalographic (EEG) parameters. These parameters are used to estimate the depth of halothane anesthesia...
Temporal changes in neuronal activity of the bilateral medial vestibular nuclei following unilateral labyrinthectomy in rats

Park BR, Lee MY, Kim MS, Lee SH, Na HJ, Doh NY

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):481-490.
To investigate the changes in the responses of vestibular neurons with time during vestibular compensation, the resting activity and dynamic responses of type I and II neurons in the medial vestibular nuclei...
Decreased voltage dependent K+ currents in cerebral arterial smooth muscle cells of one-kidney, one-clip Goldblatt hypertensive rat

Oh YS, Kim SH, Kim HS, Jeon BH, Chang SJ, Kim KJ

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):471-479.
The Kv channel activity in vascular smooth muscle cell plays an important role in the regulation of membrane potential and blood vessel tone. It was postulated that increased blood vessel tone in hypertension...
Physiological and pharmacological characterization of glutamate and GABA receptors in the retina

Yang XL, Shen Y, Han MH, Lu T

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):461-469.
Glutamate and gamma-aminobutyric acid (GABA) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, respectively. Using the whole-cell patch clamp technique and a rapid solution changer, glutamate and GABA receptors have been...
A novel mechanism of bitter taste transduction

Kaneko A, Takeuchi H, Kurahashi , Tsunenari

  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):455-459.
Bitter taste is an important warning sign for animals that food is poisonous. The transduction mechanism of bitter taste is still a contradictory matter among researchers. The major current hypothesis,...

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