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Hypothermic preconditioning lowers the incidence of hypothermic arrest in neonatal rat

Park SS, Na HS, Nam HJ, Hong SK

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):231-236.
This study was performed to examine 1) Whether hypothermic cardiac arrest produces myocardial HSP72 expression; 2) And if, whether it serves to protect the heart against the subsequent hypothermic arrest. In the present...
Thyroid hormone-induced alterations of Ca2+-ATPase and phospholamban protein expression in cardiac sarcoplasmic reticulum

Kim HW, Noh KM, Park M, Lee HR, Lee EH

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):223-230.
Alterations of cardiovascular function associated with various thyroid states have been studied. In hyperthyroidism left ventricular contractility and relaxation velocity were increased, whereas these parameters were decreased in hypothyroidism. The mechanisms for these changes...
Comparative effects on secretion of LH, FSH, prolactin, and testosterone by chronic and direct hypothalamic administration of nonylphenol to adult male rats

Park KS, Jang WC, Kim MK, Kim HG

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):215-222.
Nonylphenol (NP) is a widespread environmental pollutant that has been shown to exert both toxic and estrogenic effects on mammalian cells. As the effects of NP on the reproductive system of adult...
Assessment of flavin-containing monooxygenase (FMO) activity by determining urinary ratio of theobromine and caffeine in a Korean population after drinking a cup of coffee

Chung WG, Kang JH, Roh HK, Lee KH, Park CS, Cha YN

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):207-213.
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1...
Increase of intracellular Ca2+ concentration by Vibrio vulnificus cytolysin in rat platelets; triggering mechanism of platelet cytolysis

Park JB, Chae SW

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):199-205.
Vibrio vulnificus cytolysin caused platelet cytolysis and increased intracellular calcium concentration ((Ca2+))i) of rat platelets in a concentration-dependent manner. In the presence of V. vulnificus cytolysin (3 HU/ml), lactate dehydrogenase (LDH) activity was...
Effects of ethanol on Na+-dependent solute uptake in rabbit renal brush-border membrane vesicles

Kim YK, Ko SH, Woo JS, Jung JS, Lee SH

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):191-198.
This study was undertaken to examine the effect of ethanol on Na+-dependent transport systems (glucose, phosphate, and dicarboxylate) in renal brush-border membrane vesicles (BBMV). Ethanol inhibited Na+-dependent uptakes of glucose, phosphate, and succinate...
Acute pulmonary responses in vivo to silica complexed with H+, Zn2+, or Fe3+

Lee J

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):183-189.
This investigation is to determine whether the surface complexation of iron influence acute pulmonary responses induced by silica. For this study, three varieties of cation complexed silica were used: silica-H+, -Zn2+, and -Fe3+,...
Minimal amount of insulin can reverse diabetic heart function: Sarcoplasmic reticulum Ca2+ transport and phospholamban protein expression

Kim HW, Cho YS, Lee YS, Lee EH, Lee HR

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):175-182.
In the present study, the underlying mechanisms for diabetic functional derangement and insulin effect on diabetic cardiomyopathy were investigated with respect to sarcoplasmic reticulum (SR) Ca2+-ATPase and phospholamban at the transcriptional and translational...
Evidence for adenosine triphosphate (ATP) as an excitatory neurotransmitter in guinea-pig gastric antrum

Kang TM, Xu W, Kim SJ, Ahn SC, Kim YC, So I, Park MK, Uhm DY, Kim KW

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):165-174.
We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig...
Molecular analysis of AQP2 promoter. I. cAMP-dependent regulation of mouse AQP2 gene

Park MY, Lee YH, Bae HR, Lee RH, Lee SH, Jung JS

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):157-164.
To determine molecular mechanisms of Aquaporin-CD (AQP2) gene regulation, the promoter region of the AQP2 gene was examined by transiently transfecting a promoter-luciferase reporter fusion gene into mouse renal collecting duct cell lines...
Antioxidant effects of serotonin and L-DOPA on oxidative damages of brain synaptosomes

Ham SS, Kim DH, Lee SH, Kim YS, Lee CS

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):147-155.
Antioxidant effects of serotonin and L-DOPA on neuronal tissues were examined by studying the oxidative damages of brain synaptosomal components. The study further explored the mechanism by which they exert protective actions. Serotonin...
Effects of dexamethasone and DHEA on the changes of glutamate and polyamine uptake in rat astrocytes by lipopolysaccharide and antimycin A

Choi SH, Lee B, Shin KH, Min BH, Chun YS, Chun BG

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):137-146.
Interactions among dexamethasone, dehydroepiandrosterone (DHEA), lipopolysaccharide (LPS), and antimycin A on the glutamate uptake and the polyamine uptake were investigated in primary cultures of rat cerebral cortical astrocytes to examine the effects of...
Effects of dexamethasone and DHEA on the responses of rat cerebral cortical astrocytes to lipopolysaccharide and antimycin A

Choi SH, Kim HG, Kim CK, Park NH, Choi DH, Shim IS, Chun BG

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):127-135.
As part of a study on the effects of dexamethasone and dehydroepiandrosterone (DHEA) on the biological roles of astrocytes in brain injury, this study evaluated the effects of dexamethasone and DHEA on the...
Properties of spontaneous activity in gastric smooth muscle

Suzuki H, Yamamoto Y, Hirst G

  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):119-125.
Mammalian gastric smooth muscles generate spontaneous rhythmic contractions which are associated with slow oscillatory potentials (slow waves) and spike potentials. Spike potentials are blocked by organic Ca2+-antagonists, indicating that these result from the activation...

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