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12 results

Inhibitory effects of reversible proton pump inhibitors YH 1238 and YH1885 on acid secretion in isolated gastric cells

Kim H, Kim DG, Lee BY, Lee JW, Kim KH

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):337-343.
Antiulcer effects of YH1238 and YH1885 were determined in the isolated gastric cells from human and rabbit stomach. Intracellular accumulation of (14C)-aminopyrine and (14C)-glucose oxidation were used as indicators of acid secretory ability...
Renal effects of chronic treatment of adenosine analogues

Kim TH, Kim SH, Huh J, Cho KW

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):325-335.
Evidence for the existence of at least two subclasses of renal adenosine receptors has been presented. N-6-cyclohexyladenosine (CHA) is a relatively selective A-1 adenosine agonists, whereas 5'-N-ethylcarboxamidoadenosine (NECA) acts as a preferential agonist...
Renal functional responses to a centrally-administered 5-HT-1A agonist in the anesthetized rabbits

Lim YC, Kim KS, Kook YJ, Koh JT

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):315-323.
Central tryptaminergic system has been shown to play an important role in the regulation of renal function: 5-HT-1 (5-hydroxytryptamine-1) receptors might seem to mediate the diuresis and natriuresis, whereas the 5-HT-2 and 5-HT-3...
Regulatory role of cyclic nucleotides in non-adrenergic non-cholinergic relaxation of lower esophageal sphincter from dogs

Kim YT, Rhim BY

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):303-313.
The role of the lower esophageal sphincter (LES) is characterized by the ability to maintain tone and to relax allowing the passage of a bolus. It is known that LES relaxation during...
Inhibition by higenamine of lipopolysaccharide-induced iNOS and mRNA expression and NO production in rat aorta

Kang YJ, Lee GW, Ku EB, Lee HY, Chang KC

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):297-302.
Higenamine was widely used as traditional remedy for the treatment of rheumatoid arthritis. Nitric oxide (NO) may be a critical mediator in this inflammatory disease. Synovial tissue from humans with inflammatory arthritis expresses...
Effect of glial-neuronal cell co-culture on GFAP expression of astrocytes

Bae H, Park J, Yeon D

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):285-296.
Injury to brain transforms resting astrocytes to their reactive form, the hallmark of which is an increase in glial fibrillary acidic protein (GFAP), the major intermediate filament protein of their cell type....
Effect of electrical stimulation of the vestibular system on vestibuloocular reflex and c-Fos expression in the medial vestibular nuclei of unilateral labyrinthectomized rats

Park BR, Hwang HR, Lee MY, Kim MS

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):275-284.
Unilateral labyrinthectomy (ULX) causes autonomic symptoms, ocular and postural asymmetries, which disappear over time in the process of equilibrium recovery known as vestibular compensation. In the present study, in order to elucidate mechanisms...
Effects of electrical stimulation of the vestibular system on neuronal activity of the ipsilateral medial vestibular nuclei following unilateral labyrinthectomy in rats

Lee MY, Kim MS, Park BR

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):263-273.
The purpose of this study was to evaluate the effects of electrical stimulation on vestibular compensation following ULX in rats. Electrical stimulation (ES) with square pulse (100 ~ 300 uA, 1.0 ms, 100...
The changes of immunoreactivity for CGRP and SP in the spinal cord and DRG according to the distance between the DRG and injury site of a peripheral neuropathic rat

Kim HJ, Kim WK, Paik KS, Kang BS

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):251-262.
Peripheral nerve injury sometimes leads to neuropathic pain and depletion of calcitonin gene related-peptide (CGRP) and substance P (SP) in the spinal cord. However, the pathophysiological mechanisms for depletion of CGRP and SP...
Effects of electrical stimulation of brainstem nuclei on dorsal horn neuron responses to mechanical stimuli in a rat model of neuropathic pain

Leem JW, Choi Y, Gwak YS, Nam TS, Paik KS

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):241-249.
The aim of the present study is to examine the brainstem sites where the electrical stimulation produces a suppression of dorsal horn neuron responses of neuropathic rats. An experimental neuropathy was induced by...
Electrophysiological properties of the neurons dissociated from the nucleus raphe magnus in postnatal rats

Nam SC, Lim W, Cho SS, Kim J

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):233-240.
Neurons in the nucleus raphe magnus are involved in descending modulation of nociceptive transmission. In this study, we attempted to investigate electrophysiological properties of the NRM neurons dissociated from the postnatal rat medulla....
Interaction of forskolin with the effect of N-6-cyclopentyladenosine on norepinephrine release in rat hippocampus

Choi BK, Kim DK, Son Y, Yang UJ

  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):225-231.
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A-1-adenosine heteroreceptor and various lines of evidence indicate the involvement of adenylate cyclase system in A-1-adenosine...

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