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Understanding pain in Parkinson’s disease: types, predictors, and treatment approaches

Toledo JPC

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Rethinking nociplastic pain: implications for the Philippines and beyond

Lacsa JEM

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Glucagon-like peptide-1 receptor agonists in neuropathic pain: hype or hope?

Choi JI

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The power of data sharing: strengthening research integrity and advancing scientific discovery

Lacsa JEM

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Correlation between knee pain and quadriceps condition in osteoarthritis rats treated with cog polydioxanone filaments

Cha M, Nan G, Kang N, Bai SJ, Ikeda R, Lee BH, Jang JH

Background: Weakness in the quadriceps muscle significantly contributes to the development and progression of knee osteoarthritis (OA), characterized by pain and impaired function. This study aimed to assess structural and...
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Pain assessment using the Analgesia Nociception Index in patients undergoing sedation: a systematic review and meta-analysis

Kim MK, Lee OH, Choi GJ, Kang H

Background: This systematic review and meta-analysis analyzed the utility of the Analgesia Nociception Index (ANI) in detecting intraoperative and procedural pain in sedated patients. Methods: A comprehensive search of the Cochrane...
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Evaluation of the efficacy of the lumbar sympathetic ganglion block and the use of perfusion index as a predictor of its technical success: a prospective observational study

Nam S, Lee S, Yoon SH, Lee HJ, Moon JY, Yoo Y, Kim J

Background: This study aimed to evaluate the 4-week clinical efficacy of the lumbar sympathetic ganglion block (LSGB), assess the perfusion index (PI) as a marker for the LSGB’s technical success,...
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Efficacy of intravenous acetaminophen as adjunct analgesia in patients undergoing cardiovascular surgery: a systematic review and meta-analysis

Lee S, Koo CH, Bae YK, Ryu JH

Background: Although intravenous (IV) acetaminophen (AAP) may help reduce severe postoperative pain and opioid use after cardiovascular surgery, its effectiveness must be further validated. Therefore, the authors aimed to evaluate...
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Knowledge, mechanisms, and intervention of the polytrauma clinical triad in military pain medicine

Liu Q, Qiu P, Ma T, Zhao Y, Fu S, Gao M, Feng Z, Feng L

This up-to-date review focused on the recent advances in the concept, interrelationship, and mechanisms of the polytrauma clinical triad (PCT), and intervention knowledge and approaches to its prevention and treatment...
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Effects of unpredictable chronic mild stress of female rats before pregnancy on morphineinduced antinociceptive tolerance in offspring

Rashidi NR, Khodayari N, Sadegh M, Karami H, Ghaffari MK, Gholami M

Background: Prenatal chronic stress can impact pain sensitivity and analgesic responses in offspring. This study investigates oxidative stress markers in the ovaries of female rats that experienced unpredictable chronic mild...
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Effect of glucagon-like peptide-1 receptor agonist on paclitaxel induced neurotoxicity in dorsal root ganglion neuronal cells in vitro

Jung Y, Park S, Lim WY, Hong J, Baik J, Lee HJ, Kwon JY, Kim E

Background: Chemotherapy is the basis of cancer treatment. Chemotherapy-induced peripheral neuropathy (CIPN) is a major adverse effect. CIPN has a high incidence rate and substantially affects the quality of life...
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MiR-298 suppresses astrocytic NF-κB activity and neuroinflammation via targeting MyD88 in bone cancer pain

Liu M, Wang D, Yan Z, Zhou M

Background: Bone cancer pain (BCP), a major symptom impairing quality of life and mobility in cancer patients, is linked to microRNAs dysregulation. This study investigates the role of miR-298 in...
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Ratio of excitatory and inhibitory synaptic processes in periaqueductal gray matter of the brain activated by the raphe magnus nucleus in a model of Parkinson’s disease with hydrocortisone protection

Stepanyan H, Poghosyan M, Hovsepyan M, Sargsyan R, Danielyan M, Minasyan A, Hunanyan N, Karapetyan K, Sarkissian J

Background: The involvement of antinociceptive centers in neurodegeneration within the brain, particularly in Parkinson’s disease (PD), which is accompanied by chronic pain, is not yet well understood. Methods: Electrophysiological recordings were...
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Two-year prognosis of primary stabbing headache and its associated factors: a clinic-based study

Cho S, Kim BK

Background: Primary stabbing headache (PSH) is commonly seen in headache clinics, yet its long-term course remains inadequately explored. This study aimed to determine the 2-year recurrence rate of PSH and...
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