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HLA Mismatched Allogeneic Hematopoietic Stem Cell Transplantation

Kim HJ

Much of the success of hematopoietic stem cell transplantation (HSCT) has been due to the ability to overcome posttransplant complications, by performing HLA genotypically matched or even mismatched sibling donor...
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A Case of Polycythemia Vera Combined with Focal Segmental Glomerulosclerosis

Park MO, Baek HJ, Song SY

Polycythemia vera (PV) is a myeloproliferative disorder that results from clonal expansion of a transformed hematopoietic stem cell, and this is associated with a prominent overproduction of erythrocytes, and to...
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A Case of Autoerythrocyte Sensitization Syndrome in an Adult Male

Shin HS, Park CH, Lee CW, Je HJ, Kang HD, Lee SH

Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome), also known as painful bruising syndrome or psychogenic purpura, is characterized by sudden and spontaneous painful bruising and swelling on both extremities, and is a...
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A Case of Idiopathic CD4+ T-lymphocytopenia Associated with Autoimmune Hemolytic Anemia

Lee SG, Byun SH, Choi JW, Kim HS

Idiopathic CD4+ T-lymphocytopenia (ICL) is defined by the CDC as depressed numbers of circulating CD4+ T-lymphocytes (
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A Case of Heparin Induced Thrombocytopenia with Circulating Anti-PF4/Heparin Antibody

Lee Y, Kim J, Song J, Song KS

Heparin-induced thrombocytopenia (HIT) is usually caused by anti-platelet factor 4 (PF4)/heparin antibodies, leading to intravascular platelet activation. Circulating anti-PF4/heaprin antibody (IgG, IgA and IgM) was detected by ELISA (Asserachrom HPIA, Diagnostia Stago,...
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A Case of Myelodysplastic Syndrome Associated with an Isolated del(5q) Chromosomal Abnormality Showing Poor Prognosis

Chung HJ, Park CJ, Chi HS, Jang S, Seo EJ, Lee JH

Typical myelodysplastic syndrome (MDS) associated with isolated del(5q) consists of an interstitial deletion of the band between q13 and q33 on chromosome 5. Generally, patients with isolated deletion 5q have...
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Differentially Expressed Cellular Gene Profiles between Healthy HIV-infected Koreans and AIDS Patients

Choi JH, Choi BS, Kim SS, Lee JS

BACKGROUND: The global effect of HIV infection on the host cell gene expression profiles in healthy HIV-infected patients, as long-term non-progressors, remains largely unknown. To identify the cellular genes related...
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A Case of Hemophagocytic Lymphohistiocytosis Accompanied by Acute Hepatitis A: Review of the Literature

Lee HJ, Chung JS, Shin HJ, Choi YJ, Park YE, Kim PJ, Kim ID, Lee EY, Cho GJ

A previously healthy 26-year-old female was referred to our hospital because of fever and abnormalities of her blood biochemistry. Her laboratory results displayed leukopenia (1.79x103/microliter), thrombocytopenia (85x103/microliter), the serum aspartate...
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Susceptibility of Leukemia according to the Genotype of Minor Histocompatibility Antigens in a Korean Population

Park MJ, Choi HB, Yoon HY, Choi EJ, Kim SY, Kim HJ, Eom KS, Lee S, Kim DW, Lee JW, Min WS, Kim CC, Kim TG

BACKGROUND: In the search for susceptibility genes responsible for leukemia, genetic studies involving HLA association have been in progress extensively since the first report on its effect on the disease....
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Role of Pertussis Toxin-sensitive G Protein-coupled Receptor Signaling in the Proliferation of Bone Marrow Mesenchymal Stem Cells

Kim SW, Hwang JH, Jin SA, Yun GW, Yang YJ, Park NW, Lee HJ, Yun HJ, Jo DY, Kim S

BACKGROUND: Bone marrow (BM) mesenchymal stem cells (MSCs) can be expanded over 20~30 cell doublings in vitro even in the absence of any growth factors. However, the mechanisms that govern...
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