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Clinical Efficacy of Thalidomide Containing Regimens as a Primary Therapy in Patients with Multiple Myeloma

Jeong SH, Lee JJ, Sohn SK, Shin HJ, Yang DH, Kim YK, Kim SK, Baek JH, Kim DH, Kim JG, Chung JS, Cho GJ, Kim HJ

BACKGROUND: The aim of this study was to assess the efficacy and toxicity of thalidomide-containing regimens as the first-line therapy for patients with multiple myeloma. METHODS: A total of 60 patients...
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A Case of Hyperhomocysteinemia Manifested by Deep Vein Thrombosis and Pulmonary Embolism

Lee SH, Choi SH, Lee JH, Seon KY, Joo SB

Homocysteine has been reported as an independent risk factor of intravascular thrombosis and atherosclerosis by its participation in vascular endothelial cell dysfunction, platelet activation and thrombus formation. The serum homocysteine...
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A Novel Jumping Translocation of 12q21 in a Patient with Chronic Idiopathic Myelofibrosis

Cho HS, Hyun MS

Jumping translocation (JT) has been defined as the translocation involving one donor chromosome and multiple recipient chromosomes in different cell lines in the same patient. This is rarely observed in...
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Impact of Day +11 Methotrexate on the Incidence of Graft-versus-host Disease after HLA-identical Allogeneic Peripheral Blood Stem Cell Transplantation

Ahn BM, Jung YR, Lee KB, Sohn SK, Kim JG, Baek JH, Cho YY, Chae YS, Jeon SB, Moon JH, Kim SN, Lee SJ, Suh JS, Lee KS

BACKGROUND: Cyclosporine (CSA) plus 4 doses of methotrexate (MTX) is the commonly used regimen for GVHD prophylaxis. It has been previously found that the omission of the day +11 dose...
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Two Cases of Cytomegalovirus Pneumonia after CD34 Selected Autologous Stem Cell Transplantation

Kwon YL, Joeng JK, Kim GY, Kim SR, Lee SY, Youn YD, Lee JL, Lee WS, Kwon GY, Park JH

Cytomegalovirus (CMV) pneumonia is an important cause of treatment related mortality after allogeneic stem cell transplantation (SCT) and autologous SCT, particularly in a CD34 selected setting. There is little known...
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CD56+ T-cell Prolymphocytic Leukemia Showing a High Expression Level of TCL1 Oncogene: A Case Report with a Review of the Literature

Yun HK, Shin MG, Kim HJ, Kim HR, Park JY, Cho D, Kee SJ, Kim YH, Shin JH, Suh SP, Ryang DW

T-cell prolymphocytic leukemia (T-PLL) is a rare mature post-thymic T-cell malignancy with infiltration to the blood, bone marrow, lymph node, liver, spleen and skin; this disease has a poor prognosis...
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A Case of Primary Hepatic B-cell Lymphoma of Mucosa-associated Lymphoid Tissue (MALT)-Type

Kim SR, Kang BJ, Eum SW, Kim DY, Joo YH, Chang SH, Lee JH, Lee YB

Mucosa-associated lymphoid tissue (MALT) lymphoma is a low grade B cell lymphoma that, occurs in numerous sites including the stomach, ocular adnexa, thyroid, lung and breast; however, primary hepatic lymphoma...
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A Case of an Untreated Acute Myeloid Leukemia Patient with Invasive Aspergillosis that Developed at the Colon

Moon JY, Choi YJ, Shin HJ, Chung JS, Song MK, Han DC, Park JY, Kim KY, Kim HW, Cho GJ

Invasive aspergillosis needs to be paid extra attention to these day since chemotherapy and stem cell transplantation bring about immune suppression. The lung is the main portal of entry and...
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Tumor Lysis Syndrome in Lymphoblastic Crisis of CML

Lee DJ, Choi CU, Lee CS, Lee HH, Park JK, Choi JH, Lee YY, Kim IS

Tumor lysis syndrome (TLS) defines the metabolic derangements that occur with tumor breakdown following the initiation of cytotoxic therapy. TLS results from the rapid destruction of malignant cells and the...
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Low-dose All-trans Retinoic Acid for Remission Induction of Acute Promyelocytic Leukemia in Acute Renal Failure

Park HW, Choi JH, Lee D, Koo DH, Koo JE, Kim SH, Lee JH, Lee JH, Lee KH

All-trans retinoic acid (ATRA) is the standard induction treatment for acute promyelocytic leukemia (APL). Renal involvement sometimes necessitates a dose reduction or discontinuation of induction therapy for hematological malignancies. We...
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Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation with Non-Myeloablative Conditioning: Experiences at a Single Center

Na II, Shin H, Song EK, Lee KW, Yun T, Kim JH, Yoon SS, Lee JS, Park S, Kim BK

BACKGROUND: The use of non-myeloablative stem cell transplantation (NST) has recently been increasing for treating the patients who cannot tolerate ablative hematopoietic stem cell transplantation (HSCT). Although graft-versus-host disease (GVHD)...
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